Occultation Light Curves of Io's Hot Spots in 2014

We present ground-based observations of Io during Spring 2014, contributing to decadal timelines of individual hot spots' volcanic activity

Potential for Solar System Science with the ngVLA

Radio wavelength observations of solar system bodies are a powerful method of probing many characteristics of those bodies. From surface and subsurface, to atmospheres (including deep atmospheres of the giant planets), to rings, to the magnetosphere of Jupiter, these observations provide unique information on current state, and sometimes history, of the bodies. The ngVLA will enable the highest sensitivity and resolution observations of this kind, with the potential to revolutionize our understanding of some of these bodies. In this article, we present a review of state-of-the-art radio wavelength observations of a variety of bodies in our solar system, varying in size from ring particles and small near-Earth asteroids to the giant planets. Throughout the review we mention improvements for each body (or class of bodies) to be expected with the ngVLA. A simulation of a Neptune-sized object is presented in Section 6. Section 7 provides a brief summary for each type of object, together with the type of measurements needed for all objects throughout the Solar System

Occultation Light Curves of Io's Hot Spots in 2014

We present ground-based observations of Io during Spring 2014, contributing to decadal timelines of individual hot spots' volcanic activity

A Nearby M Star with Three Transiting Super-Earths Discovered by K2

Small, cool planets represent the typical end-products of planetary formation. Studying the architectures of these systems, measuring planet masses and radii, and observing these planets' atmospheres during transit directly informs theories of planet assembly, migration, and evolution. Here we report the discovery of three small planets orbiting a bright (K_s = 8.6 mag) M0 dwarf using data collected as part of K2, the new ecliptic survey using the re-purposed Kepler spacecraft. Stellar spectroscopy and K2 photometry indicate that the system hosts three transiting planets with radii 1.5–2.1 R_⊕, straddling the transition region between rocky and increasingly volatile-dominated compositions. With orbital periods of 10–45 days the planets receive just 1.5–10× the flux incident on Earth, making these some of the coolest small planets known orbiting a nearby star; planet d is located near the inner edge of the system's habitable zone. The bright, low-mass star makes this system an excellent laboratory to determine the planets' masses via Doppler spectroscopy and to constrain their atmospheric compositions via transit spectroscopy. This discovery demonstrates the ability of K2 and future space-based transit searches to find many fascinating objects of interest

Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?

Juvenile idiopathic arthritis (JIA) is a disease characterized by chronic joint inflammation, caused by a deregulated immune response. In patients with JIA, heat shock proteins (HSPs) are highly expressed in the synovial lining tissues of inflamed joints. HSPs are endogenous proteins that are expressed upon cellular stress and are able to modulate immune responses. In this review, we concentrate on the role of HSPs, especially HSP60, in modulating immune responses in both experimental and human arthritis, with a focus on JIA. We will mainly discuss the tolerogenic immune responses induced by HSPs, which could have a beneficial effect in JIA. Overall, we will discuss the immune modulatory capacity of HSPs, and the underlying mechanisms of HSP60-mediated immune regulation in JIA, and how this can be translated into therapy

Systematic construction of qualitative physics-based rules for process diagnostics

A novel first-principles-based expert system is proposed for on-line detection and identification of faulty component candidates during incipient off-normal process operations. The system performs function-oriented diagnostics and can be reused for diagnosing single-component failures in different processes and different plants through the provision of the appropriate process schematics information. The function-oriented and process-independent diagnostic features of the proposed expert system are achieved by constructing a knowledge base containing three distinct types of information, qualitative balance equation rules, functional classification of process components, and the process piping and instrumentation diagram. The various types of qualitative balance equation rules for processes utilizing single-phase liquids are derived and their usage is illustrated through simulation results of a realistic process in a nuclear power plant

Automatic systems diagnosis without behavioral models

Recent feedback obtained while applying Model-based diagnosis (MBD) in industry suggests that the costs involved in behavioral modeling (both expertise and labor) can outweigh the benefits of MBD as a high-performance diagnosis approach. In this paper, we propose an automatic approach, called ANTARES, that completely avoids behavioral modeling. Decreasing modeling sacrifices diagnostic accuracy, as the size of the ambiguity group (i.e., components which cannot be discriminated because of the lack of information) increases, which in turn increases misdiagnosis penalty. ANTARES further breaks the ambiguity group size by considering the component's false negative rate (FNR), which is estimated using an analytical expression. Furthermore, we study the performance of ANTARES for a number of logic circuits taken from the 74XXX/ISCAS benchmark suite. Our results clearly indicate that sacrificing modeling information degrades the diagnosis quality. However, considering FNR information improves the quality, attaining the diagnostic performance of an MBD approach