2,295 research outputs found
Energy loss mechanism for suspended micro- and nanoresonators due to the Casimir force
A so far not considered energy loss mechanism in suspended micro- and
nanoresonators due to noncontact acoustical energy loss is investigated
theoretically. The mechanism consists on the conversion of the mechanical
energy from the vibratory motion of the resonator into acoustic waves on large
nearby structures, such as the substrate, due to the coupling between the
resonator and those structures resulting from the Casimir force acting over the
separation gaps. Analytical expressions for the resulting quality factor Q for
cantilever and bridge micro- and nanoresonators in close proximity to an
underlying substrate are derived and the relevance of the mechanism is
investigated, demonstrating its importance when nanometric gaps are involved
Dark Sector from Interacting Canonical and Non-Canonical Scalar Fields
In this work it is investigated general models with interactions between two
canonical scalar fields and between one non-canonical (tachyon-type) and one
canonical scalar field. The potentials and couplings to the gravity are
selected through the Noether symmetry approach. These general models are
employed to describe interactions between dark energy and dark matter, with the
fields being constrained by the astronomical data. The cosmological solutions
of some cases are compared with the observed evolution of the late Universe.Comment: 20 pages, 13 figures, correction of misprints in eqs. (4), (5), (43),
(44
Mirror Dark Matter and Core Density of Galaxies
We present a particle physics realization of a recent suggestion by Spergel
and Steinhardt that collisional but dissipationless dark matter may resolve the
core density problem in dark matter-dominated galaxies such as the dwarf
galaxies. The realization is the asymmetric mirror universe model introduced to
explain the neutrino puzzles and the microlensing anomaly. The mirror baryons
are the dark matter particles with the desired properties. The time scales are
right for resolution of the core density problem and formation of mirror stars
(MACHOs observed in microlensing experiments). The mass of the region
homogenized by Silk damping is between a dwarf and a large galaxy.Comment: 9 pages, LaTex. The present version shows that atomic scattering
inherent in the mirror model can solve the core density problem without the
need for an extra U(1) discussed in the original version; all conclusions are
unchanged. This version is accepted for publication in Phys. Rev.
Mirror Dark Matter
There appear to be three challenges that any theory of dark matter must face:
(i) why is of the same order as ? (ii) what
are the near solar mass objects () observed by the MACHO
microlensing project ? and (iii) understanding the shallow core density profile
of the halos of dwarf as well as low surface brightness galaxies. The popular
cold dark matter candidates, the SUSY LSP and the axion fail to meet these
challenges. We argue that in the mirror model suggested recently to explain the
neutrino anomalies, the mirror baryons being 15-20 times heavier than familiar
baryons, can play the role of the cold dark matter and provide reasonable
explanation of all three above properties without extra assumptions.Comment: Latex, 10 pages; Invited talk presented in PASCOS99 workshop, held in
Lake Tahoe, Dec. 1999 and DM2000 workshop held in Los Angeles, February, 200
Galactic Bulge Microlensing Optical Depth from EROS-2
We present a new EROS-2 measurement of the microlensing optical depth toward
the Galactic Bulge. Light curves of clump-giant stars
distributed over of the Bulge were monitored during seven Bulge
seasons. 120 events were found with apparent amplifications greater than 1.6
and Einstein radius crossing times in the range 5 {\rm d}.
This is the largest existing sample of clump-giant events and the first to
include northern Galactic fields. In the Galactic latitude range
1.4\degr<|b|<7.0\degr, we find with . These results are in good
agreement with our previous measurement, with recent measurements of the MACHO
and OGLE-II groups, and with predictions of Bulge models.Comment: accepted A&A, minor revision
A New Minimal-Stress Freely-Moving Rat Model for Preclinical Studies on Intranasal Administration of CNS Drugs
Purpose. To develop a new minimal-stress model for intranasal administration in freely moving rats and to evaluate in this model the brain distribution of acetaminophen following intranasal versus intravenous administration. Methods. Male Wistar rats received one intranasal cannula, an intra-cerebral microdialysis probe, and two blood cannulas for drug administration and serial blood sampling respectively. To evaluate this novel model, the following experiments were conducted. 1) Evans Blue was administered to verify the selectivity of intranasal exposure. 2) During a 1 min infusion 10, 20, or 40 Όl saline was administered intranasally or 250 ”l intravenously. Corticosterone plasma concentrations over time were compared as biomarkers for stress. 3) 200 ”g of the model drug acetaminophen was given in identical setup and plasma, and brain pharmacokinetics were determined. Results. In 96 % of the rats, only the targeted nasal cavity was deeply colored. Corticosterone plasma concentrations were not influenced, neither by route nor volume of administration. Pharmacokinetics of acetaminophen were identical after intravenous and intranasal administration, although the Cmax in microdialysates was reached a little earlier following intravenous administration. Conclusion. A new minimal-stress model for intranasal administration in freely moving rats has been successfully developed and allows direct comparison with intravenous administration. KEY WORDS: acetaminophen; brain; intranasal infusion; microdialysis; pharmacokinetics
Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma
Observation of periodic variable stars towards the galactic spiral arms by EROS II
We present the results of a massive variability search based on a photometric
survey of a six square degree region along the Galactic plane at (, ) and (, ). This
survey was performed in the framework of the EROS II (Exp\'erience de Recherche
d'Objets Sombres) microlensing program. The variable stars were found among
1,913,576 stars that were monitored between April and June 1998 in two
passbands, with an average of 60 measurements. A new period-search technique is
proposed which makes use of a statistical variable that characterizes the
overall regularity of the flux versus phase diagram. This method is well suited
when the photometric data are unevenly distributed in time, as is our case.
1,362 objects whose luminosity varies were selected. Among them we identified 9
Cepheids, 19 RR Lyrae, 34 Miras, 176 eclipsing binaries and 266 Semi-Regular
stars. Most of them are newly identified objects. The cross-identification with
known catalogues has been performed. The mean distance of the RR Lyrae is
estimated to be kpc undergoing an average absorption of
magnitudes. This distance is in good agreement with the one
of disc stars which contribute to the microlensing source star population.Our
catalogue and light curves are available electronically from the CDS,
Strasbourg and from our Web site http://eros.in2p3.fr.Comment: 15 pages, 11 figures, accepted in A&A (april 2002
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