Prevalência de sobrepeso e obesidade em adolescentes de escolas públicas Municipais em Campina Grande-PB / Prevalence of overweight and obesity in adolescents from Municipal public schools in Campina Grande-PB

Atualmente, sobrepeso e obesidade são caracterizados como epidemias de caráter mundial que acarretam comorbidades de curto à longo prazo. Em crianças e adolescentes, os valores crescem rapidamente e as intervenções devem ser feitas de forma precoce. O estudo busca avaliar a prevalência de sobrepeso e obesidade em alunos do 5° ao 9° ano do Ensino Fundamental, com idade entre 10 a 16 anos de escolas públicas municipais da cidade de Campina Grande - PB. O estudo transversal e descritivo, foi composto por 574 alunos, sendo 294 do sexo feminino e 280 do sexo masculino. Os indicadores utilizados para avaliação do estado nutricional foram IMC/Idade e Estatura/Idade. De acordo com o IMC/Idade, os alunos foram classificados com magreza, eutrofia, sobrepeso e obesidade. Também foram classificados com muito baixa estatura para a idade, baixa estatura para a idade, estatura adequada para a idade e alta estatura, considerando o indicador Estatura/Idade. Os resultados obtidos mostram a prevalência de sobrepeso em maior número no sexo feminino (16%), já na obesidade, a prevalência foi mais acentuada no sexo masculino (9,6%). Juntos, sobrepeso e obesidade classificam (21,6%) dos alunos avaliados. Os valores observados são condizentes com estudos feitos em demais localidades no país, sendo de caráter relevante a adoção de intervenções para redução dessa estatística crescente. O apoio de equipes multiprofissionais de saúde, juntamente com o auxílio das escolas que mostram um papel fundamental no processo contínuo de educação, são de extrema relevância

From Data to Software to Science with the Rubin Observatory LSST

The Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) dataset will dramatically alter our understanding of the Universe, from the origins of the Solar System to the nature of dark matter and dark energy. Much of this research will depend on the existence of robust, tested, and scalable algorithms, software, and services. Identifying and developing such tools ahead of time has the potential to significantly accelerate the delivery of early science from LSST. Developing these collaboratively, and making them broadly available, can enable more inclusive and equitable collaboration on LSST science. To facilitate such opportunities, a community workshop entitled "From Data to Software to Science with the Rubin Observatory LSST" was organized by the LSST Interdisciplinary Network for Collaboration and Computing (LINCC) and partners, and held at the Flatiron Institute in New York, March 28-30th 2022. The workshop included over 50 in-person attendees invited from over 300 applications. It identified seven key software areas of need: (i) scalable cross-matching and distributed joining of catalogs, (ii) robust photometric redshift determination, (iii) software for determination of selection functions, (iv) frameworks for scalable time-series analyses, (v) services for image access and reprocessing at scale, (vi) object image access (cutouts) and analysis at scale, and (vii) scalable job execution systems. This white paper summarizes the discussions of this workshop. It considers the motivating science use cases, identified cross-cutting algorithms, software, and services, their high-level technical specifications, and the principles of inclusive collaborations needed to develop them. We provide it as a useful roadmap of needs, as well as to spur action and collaboration between groups and individuals looking to develop reusable software for early LSST science.Comment: White paper from "From Data to Software to Science with the Rubin Observatory LSST" worksho

From Data to Software to Science with the Rubin Observatory LSST

editorial reviewedThe Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) dataset will dramatically alter our understanding of the Universe, from the origins of the Solar System to the nature of dark matter and dark energy. Much of this research will depend on the existence of robust, tested, and scalable algorithms, software, and services. Identifying and developing such tools ahead of time has the potential to significantly accelerate the delivery of early science from LSST. Developing these collaboratively, and making them broadly available, can enable more inclusive and equitable collaboration on LSST science. To facilitate such opportunities, a community workshop entitled "From Data to Software to Science with the Rubin Observatory LSST" was organized by the LSST Interdisciplinary Network for Collaboration and Computing (LINCC) and partners, and held at the Flatiron Institute in New York, March 28-30th 2022. The workshop included over 50 in-person attendees invited from over 300 applications. It identified seven key software areas of need: (i) scalable cross-matching and distributed joining of catalogs, (ii) robust photometric redshift determination, (iii) software for determination of selection functions, (iv) frameworks for scalable time-series analyses, (v) services for image access and reprocessing at scale, (vi) object image access (cutouts) and analysis at scale, and (vii) scalable job execution systems. This white paper summarizes the discussions of this workshop. It considers the motivating science use cases, identified cross-cutting algorithms, software, and services, their high-level technical specifications, and the principles of inclusive collaborations needed to develop them. We provide it as a useful roadmap of needs, as well as to spur action and collaboration between groups and individuals looking to develop reusable software for early LSST science

Ultrasound-assisted extraction and encapsulation by spray drying of bioactive compounds from Tradescantia zebrina leaves

This study investigated the ultrasound-assisted extraction of bioactive compounds from Tradescantia zebrina leaves and the subsequent encapsulation of the extract by spray drying. The optimum extraction conditions for phenolic compounds and anthocyanins contents corresponded to 6.25 min, 60 °C, and 20 % amplitude. A higher number of compounds were identified in the ultrasound-treated extract when compared to the control not subjected to ultrasound. The microparticles showed encapsulation efficiency of 98 %, hygroscopicity of 7.50 %, phenolics content of 92.25 mg of GAE/g, and anthocyanins content of 0.014 mg cyanidin-3-glucoside/g. The particle size ranged from 7 to 100 nm, and FTIR analysis proved the presence of bioactive compounds in the sample. SEM images showed the effectiveness of the encapsulation process. Differences were observed in the color parameters L, a*, and b*. Regarding the sensory evaluation, no differences were observed between the control yogurt and the yogurt made with the addition of 4 % microparticles. The concentration of bioactive compounds at the end of the in vitro digestion remained sufficient to bring benefits to the consumer. Therefore, the encapsulated extract of Tradescantia zebrina is an effective alternative to the artificial colorings used in the food industry and can enrich the food with other bioactive compounds

Evaluation of anti-lived and anti-fixed- Leishmania (Viannia) braziliensis promastigotes IgG antibodies detected by flow cytometry for diagnosis and post-therapeutic cure assessment in localized cutaneous leishmaniasis

Submitted by Nuzia Santos ([email protected]) on 2014-06-17T14:43:21Z No. of bitstreams: 1 Evaluation of anti-lived and anti-fixed- Leishmania (Viannia) braziliensis promastigotes IgG .pdf: 1302398 bytes, checksum: 22a497d8d77df6cf087a9b6f0a0c93a6 (MD5)Made available in DSpace on 2014-06-17T14:43:21Z (GMT). No. of bitstreams: 1 Evaluation of anti-lived and anti-fixed- Leishmania (Viannia) braziliensis promastigotes IgG .pdf: 1302398 bytes, checksum: 22a497d8d77df6cf087a9b6f0a0c93a6 (MD5) Previous issue date: 2012State of Pernambuco Research Foundation (FACEPE), by the Brazilian National Research Council (CNPq), and by the Oswaldo Cruz Foundation (FIOCRUZ).Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brazil/Universidade Estadual de Montes Claros. Montes Claros, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou.Belo Horizonte, MG, Brazil/Centro Universitário Newton Paiva. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou.Belo Horizonte, MG, BrazilThis study aims to investigate a flow cytometry performance–based methodology to detect anti-live (FC-ALPA-IgG) and anti-fixed (FC-AFPA-IgG) Leishmania (Viannia) braziliensis promastigote IgG as a means to monitor post-therapeutic cure of patients with localized cutaneous leishmaniasis (LCL). Serum samples from 30 LCL patients infected with L. (V.) braziliensis were assayed, comparing the IgG reactivity before and after specific treatment with pentavalent antimonial. Reactivities were reported as the percentage of positive fluorescent parasites (PPFP), using a PPFP of 60% as a cut-off value. In the serum dilution of 1:1024, the positive percentage of LCL serum sample for FC-ALPA-IgG and FC-AFPA-IgG was 86% and 90%, respectively, before treatment. Analysis of ∆PPFP that represents the difference between PPFP after and before treatment appeared as a new approach to monitor post-therapeutic IgG reactivity in LCL. Our data support the perspective of using FC-ALPA and FC-AFPA as a useful serologic tool for diagnosis and for post-therapeutic follow-up of LCL patients

Evaluation of a Propolis Water Extract Using a Reliable RP-HPLC Methodology and In Vitro and In Vivo Efficacy and Safety Characterisation

Since the beginning of propolis research, several groups have studied its antibacterial, antifungal, and antiviral properties. However, most of these studies have only employed propolis ethanolic extract (PEE) leading to little knowledge about the biological activities of propolis water extract (PWE). Based on this, in a previous study, we demonstrated the anti-inflammatory and immunomodulatory activities of PWE. In order to better understand the equilibrium between effectiveness and toxicity, which is essential for a new medicine, the characteristics of PWE were analyzed. We developed and validated an RP-HPLC method to chemically characterize PWE and PEE and evaluated the in vitro antioxidant/antimicrobial activity for both extracts and the safety of PWE via determining genotoxic potential using in vitro and in vivo mammalian micronucleus assays. We have concluded that the proposed analytical methodology was reliable, and both extracts showed similar chemical composition. The extracts presented antioxidant and antimicrobial effects, while PWE demonstrated higher antioxidant activity and more efficacious for the most of the microorganisms tested than PEE. Finally, PWE was shown to be safe using micronucleus assays