A report on a collection of Ceratopogonidae (Diptera) from Rondonia, Brazil. 2. Tribes Heteromuiini and Sphaeromiini

Examination of a large collection of Ceratopogonidae from Rondonia, Brazil, resulted in records of 11 species in the tribes Heteromyiini and Sphaeromiini, including the NEW GENUS Groganhelea Spinelli & Dippolito NEWGENUS, which is described herein, with its type-species G. rondoniensis Spinelli & Dippolito, NEW SPECIES. Heteromyia correntina Lane & Duret and Mallochohelea termophila (Spinelli) are recorded for the first time from Brazil

A Report on a Collection of Ceratopogonidae (Diptera) from Rondonia, Brazil. 2. Tribes Heteromuiini and Sphaeromiini

Examination of a large collection of Ceratopogonidae from Rondonia, Brazil, resulted in records of 11 species in the tribes Heteromyiini and Sphaeromiini, including the NEW GENUS Groganhelea Spinelli & Dippolito NEWGENUS, which is described herein, with its type-species G. rondoniensis Spinelli & Dippolito, NEW SPECIES. Heteromyia correntina Lane & Duret and Mallochohelea termophila (Spinelli) are recorded for the first time from Brazil

A report on a collection of Ceratopogonidae (Diptera) from Rondonia (Brazil) and Iquitos (Peru), 1. Tribes Palpomyiini and Stenoxenini

Examination of two large collections of Ceratopogonidae from Rondonia, Brazil, and Loreto, Peru, resulted in records of 15 species in the tribes Palpomyiini and Stenoxenini, including three previously undescribed: Bezzia schmitzorum Dippolito & Spinelli, Palpomyia pseudolacustris D. & S., and Stenoxenus aductus D. & S. from Rondonia. The hitherto unknown male of Palpomyia versicolor Macfie is described and figured

A Report on a Collection of Ceratopogonidae (Diptera) from Rondonia (Brazil) and Iquitos (Peru) 1. Tribes Palpomyiini and Stenoxenini

Examination of two large collections of Ceratopogonidae from Rondonia, Brazil, and Loreto, Peru, resulted in records of 15 species in the tribes Palpomyiini and Stenoxenini, including three previously undescribed: Bezzia schmitzorum Dippolito & Spinelli, Palpomyia pseudolacustris D. & S., and Stenoxenus aductus D. & S. from Rondonia. The hitherto unknown male of Palpomyia versicolor Macfie is described and figured

Step-down compared to fixed-dose treatment with inhaled fluticasone propionate in asthma

Background: Inhaled corticosteroids (ICSs) are an effective treatment of asthma even when administered at a low dose. Once asthma is controlled, current guidelines recommend that the dose of ICS be reduced to the lowest possible and effective dose. Although the most appropriate strategy for the stepping down has not yet been defined, quantification of sputum eosinophils and bronchial hyperresponsiveness (BHR) are indeed measures of asthma control. Objective: To compare the efficacy of step-down and fixed-dose strategies in the control of BHR to methacholine and eosinophilic inflammation patients with mild-to-moderate asthma. Methods: We performed a double-blind, randomized study to compare inhaled fluticasone propionate (FP), 1,000 g/d, then reduced to 200 g/d (group 1; n 18) to a fixed dose of FP, 200 g/d (group 2; n 17) administered for 6 weeks and then 8 weeks in reducing the provocative dose of methacholine causing a 20% fall in FEV1 (PD20) and sputum eosinophils in 35 patients. The duration of the efficacy was also followed subsequently after 8 weeks of placebo treatment. Results: PD20 remarkably increased with both treatment strategies, but differences between groups were not significant. Sputum eosinophils (median values, percentage) at baseline and after each treatment period were not different (group 1, 16.4 to 1.0 to 2.7%; group 2, 16.7 to 2.8 to 2.8%, respectively). The percentages of patients in whom sputum eosinophilia was normalized (< 3%) were as follows: group 1, 69% and 60%; group 2, 50% and 57%. After placebo treatment, sputum eosinophils were still “normalized” in approximately one third of patients. Conclusion: Step-down and fixed-dose strategies with FP improved PD20 and sputum eosinophilia to a similar degree. The effect on sputum eosinophils persisted longer than that on methacholine. (CHEST 2005; 127:117–124) Key words: asthma; fluticasone propionate; inhaled steroids; sputum eosinophils Abbreviations: BHR bronchial hyperresponsiveness; CI confidence interval; FP fluticasone propionate; ICS inhaled corticosteroid; IS induced sputum; PD20 provocative dose of methacholine causing a 20% fall in FEV1; PEFR peak expiratory flow rat

Enteritis cystica profunda in Peutz-Jeghers syndrome. Report of a case and review of the literature.

The hereditary condition known as Peutz-Jeghers syndrome is characterized by mucosal pigmentation and gastrointestinal polyps. The polyps, usually pedunculated hamartomas, are significant only for the symptoms they cause. Intramural lesions also have been described with gross microscopic features that are often interpreted as malignant. Careful evaluation may show most of these lesions to be enteritis cystica profunda. These rarely diagnosed but benign tumors have very different implications for treatment and prognosis