2,904 research outputs found

    Adaptive enterprise architecture drivenagiledevelopment

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    Agile development practices focus on developing and delivering working software systems in small iterations with minimal documentation. However, locally project focused agile practices overlook the need for holistic enterprise architecture. Lack of enterprise architecture in agile, especially in the large agile environments, may lead to a number of problems such as technical debt, unnecessary re-work, inconsistent communication, locally focused isolated architecture, design and implementation. There is a missing link between the enterprise architecture and agile development. Enterprise architecture is a strategic capability that should enable and enhance agility of agile development. However, organisations are not sure how best to approach strategic enterprise architecture capability for supporting agile development. This paper proposes and demonstrate the applicability of an integrated adaptive enterprise architecture driven agile development approach for large agile environments

    Towards the Development of an Adaptive Enterprise Service System Model.

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    The continuous adaptation of modern enterprises is largely dependent on their underlying adaptive enterprise architecture capability. However, the establishment of an adaptive enterprise architecture capability requires defining the enterprise context before actually commissioning any enterprise architecture or adaptation work. This paper presents the adaptive enterprise service system (AESS) model based on the “Design Science” research method and “Theory Triangulation” approach. The AESS integrates the enterprise context perspectives from three well-known theories of agility, (agent) system, and service science. The AESS model, as a part of the large adaptive enterprise architecture toolkit, defines a modern enterprise as an adaptive enterprise service system. The adaptive enterprise service system is a multi-agent system of service systems that exhibits agility and focuses on the emerging service-centric view as opposed to a traditional product-centric view. The service-centric view of an enterprise is critical for establishing the adaptive enterprise architecture capability for handling complex enterprise transformations

    Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury.

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    PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of PAI-1 are associated with increased mortality in adults with ALI. This relationship has not been examined in children. The objective of this study was to test whether increased plasma PAI-1 levels are associated with worse clinical outcomes in pediatric patients with ALI.Design/methodsWe measured plasma PAI-1 levels on the first day of ALI among 94 pediatric patients enrolled in two separate prospective, multicenter investigations and followed them for clinical outcomes. All patients met American European Consensus Conference criteria for ALI.ResultsA total of 94 patients were included. The median age was 3.2 years (range 16 days-18 years), the PaO(2)/F(i)O(2) was 141 +/- 72 (mean +/- SD), and overall mortality was 14/94 (15%). PAI-1 levels were significantly higher in nonsurvivors compared to survivors (P < 0.01). The adjusted odds of mortality doubled for every log increase in the level of plasma PAI-1 after adjustment for age and severity of illness.ConclusionsHigher PAI-1 levels are associated with increased mortality and fewer ventilator-free days among pediatric patients with ALI. These findings suggest that impaired fibrinolysis may play a role in the pathogenesis of ALI in pediatric patients and suggest that PAI-1 may serve as a useful biomarker of prognosis in patients with ALI

    An agile enterprise architecture driven model for geographically distributed agile development

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    Agile development is a highly collaborative environment, which requires active communication (i.e. effective and efficient communication) among stakeholders. The active communication in geographically distributed agile development (GDAD) environment is difficult to achieve due to many challenges. Literature has reported that active communication play critical role in enhancing GDAD performance through reducing the cost and time of a project. However, little empirical evidence is known about how to study and establish active communication construct in GDAD in terms of its dimensions, determinants and effects on GDAD performance. To address this knowledge gap, this paper describes an enterprise architecture (EA) driven research model to identify and empirically examine the GDAD active communication construct. This model can be used by researchers and practitioners to examine the relationships among two dimensions of GDAD active communication (effectiveness and efficiency), one antecedent that can be controlled (agile EA), and four dimensions of GDAD performance (on-Time completion, on-budget completion, software functionality and software quality)

    Crowd sourcing challenges assessment index for disaster management

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    Emergency agencies (EA) rely on inter-agency approaches to information management during disasters. EA have shown a significant interest in the use of cloud-based social media such as Twitter and Facebook for crowd-sourcing and distribution of disaster information. While the intentions are clear, the question of what are its major challenges are not. EA have a need to recognise the challenges in the use of social media under their local circumstances. This paper analysed the recent literature, 2010 Haiti earthquake and 2010-11 Queensland flood cases and developed a crowd sourcing challenges assessment index construct specific to EA areas of interest. We argue that, this assessment index, as a part of our large conceptual framework of context aware cloud adaptation (CACA), can be useful for the facilitation of citizens, NGOs and government agencies in a strategy for use of social media for crowd sourcing, in preventing, preparing for, responding to and recovering from disasters. © (2012) by the AIS/ICIS Administrative Office All rights reserved
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