C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease

C-reactive protein (CRP) has been proposed as a risk factor for cardiovascular disease; however, this association is confounded by mutual relationships with both classical and haematological cardiovascular risk factors. We, therefore, measured CRP with a high-sensitivity assay in stored plasma samples from 414 men and 515 women in the north Glasgow MONICA (MONItoring trends in CArdiovascular diseases) survey, to study its correlation with haematological variables, classical risk factors and prevalent cardiovascular disease. CRP correlated with age, oral contraceptive use, menopause and most classical cardiovascular risk factors (except blood pressure). CRP also correlated with plasma levels of the pro-inflammatory cytokine interleukin 6, and haematocrit, viscosity, red cell aggregation, white cell count, and coagulation factors [fibrinogen, factor (F) VII in women, FVIII, FIX] and inhibitors (antithrombin and protein C in women; protein S) but not coagulation activation markers. CRP was significantly associated with prevalent cardiovascular disease in both men (P = 0.03) and women (P = 0.009), however, the association became non-significant after adjustment for firstly classical risk factors, then fibrinogen. We conclude that correlations with classical and haematological risk factors account for a substantial component of the association of CRP with prevalent cardiovascular disease, but there is evidence of a residual, independent effect among women

Little Alabama Coon / music by and Paley; words by Hattie Starr

Cover: photo of singer Miss Frankie M. Raymond; Publisher: Willis Woodward and Co. (New York)https://egrove.olemiss.edu/sharris_a/1021/thumbnail.jp

Image of Women and Children Sitting in front of a House

The stereograph features a black and white image of three women and seven children sitting on the porch of a house. A fourth woman sits on the balcony of the house. The image is mounted on an orange card with rounded corners. Publication information appears on the card\u27s reverse.https://scholarsjunction.msstate.edu/fvw-artifacts/1718/thumbnail.jp

Image of Women and Children Sitting in front of a House

The stereograph features a black and white image of three women and seven children sitting on the porch of a house. A fourth woman sits on the balcony of the house. The image is mounted on an orange card with rounded corners. Publication information appears on the card\u27s reverse.https://scholarsjunction.msstate.edu/fvw-photographs/1404/thumbnail.jp

Remus Takes The Cake / words by Jacob Henry Ellis

Cover: drawing of an African American male proudly walking with a large cake; description reads characteristic march and two step dance; Publisher: Willis Woodward and Co. (New York)https://egrove.olemiss.edu/sharris_a/1028/thumbnail.jp

A Rolling Window with Genetic Algorithm Approach to Sorting Aircraft for Automated Taxi Routing

With increasing demand for air travel and overloaded airport facilities, inefficient airport taxiing operations are a significant contributor to unnecessary fuel burn and a substantial source of pollution. Although taxiing is only a small part of a flight, aircraft engines are not optimised for taxiing speed and so contribute disproportionately to the overall fuel burn. Delays in taxiing also waste scarce airport resources and frustrate passengers. Consequently, reducing the time spent taxiing is an important investment. An exact algorithm for finding shortest paths based on A* allocates routes to aircraft that maintains aircraft at a safe distance apart, has been shown to yield efficient taxi routes. However, this approach depends on the order in which aircraft are chosen for allocating routes. Finding the right order in which to allocate routes to the aircraft is a combinatorial optimization problem in itself. We apply a rolling window approach incorporating a genetic algorithm for permutations to this problem, for real-world scenarios at three busy airports. This is compared to an exhaustive approach over small rolling windows, and the conventional first-come-firstserved ordering. We show that the GA is able to reduce overall taxi time with respect to the other approaches

Plan of Cumberland Meadows, Cumberland, Maine, 1986

Plan of Cumberland Meadows, Cumberland, Maine was created by Architects Four and Woodward and Curran Inc. in 1986.https://digitalmaine.com/cumberland_plans/1320/thumbnail.jp

The Dahlonega Nugget (Vol. 1, nos. 1, 3); The Dahlonega Signal (Vol. 50, no. 23)

The Dahlonega Signal: A record of mining, agricultural, local, miscellaneous and general news. The Dahlonega Nugget: Published by W. G. McNelley and S. H. Williams Covers weeks of March 14, March 28, 1890. You can also view this on https://archive.org/details/AWC_1890_3MAR/page/n7/mode/2uphttps://digitalcommons.northgeorgia.edu/cain/1024/thumbnail.jp