699 research outputs found
Excitonic Aharonov-Bohm Effect in Isotopically Pure 70Ge/Si Type-II Quantum Dots
We report on a magneto-photoluminescence study of isotopically pure 70Ge/Si
self-assembled type-II quantum dots. Oscillatory behaviors attributed to the
Aharonov-Bohm effect are simultaneously observed for the emission energy and
intensity of excitons subject to an increasing magnetic field. When the
magnetic flux penetrates through the ring-like trajectory of an electron moving
around each quantum dot, the ground state of an exciton experiences a change in
its angular momentum. Our results provide the experimental evidence for the
phase coherence of a localized electron wave function in group-IV Ge/Si
self-assembled quantum structures.Comment: 4 pages, 4 figure
Electrical Detection and Magnetic-Field Control of Spin States in Phosphorus-Doped Silicon
Electron paramagnetic resonance of ensembles of phosphorus donors in silicon
has been detected electrically with externally applied magnetic fields lower
than 200 G. Because the spin Hamiltonian was dominated by the contact hyperfine
term rather than by the Zeeman terms at such low magnetic fields, superposition
states and
were formed
between phosphorus electron and nuclear spins, and electron paramagnetic
resonance transitions between these superposition states and or states are observed clearly. A
continuous change of and with the magnetic field was
observed with a behavior fully consistent with theory of phosphorus donors in
silicon.Comment: 6 pages, 5 figure
Tracking of Normal and Malignant Progenitor Cell Cycle Transit in a Defined Niche.
While implicated in therapeutic resistance, malignant progenitor cell cycle kinetics have been difficult to quantify in real-time. We developed an efficient lentiviral bicistronic fluorescent, ubiquitination-based cell cycle indicator reporter (Fucci2BL) to image live single progenitors on a defined niche coupled with cell cycle gene expression analysis. We have identified key differences in cell cycle regulatory gene expression and transit times between normal and chronic myeloid leukemia progenitors that may inform cancer stem cell eradication strategies
An Electron-Tracking Compton Telescope for a Survey of the Deep Universe by MeV gamma-rays
Photon imaging for MeV gammas has serious difficulties due to huge
backgrounds and unclearness in images, which are originated from incompleteness
in determining the physical parameters of Compton scattering in detection,
e.g., lack of the directional information of the recoil electrons. The recent
major mission/instrument in the MeV band, Compton Gamma Ray
Observatory/COMPTEL, which was Compton Camera (CC), detected mere
persistent sources. It is in stark contrast with 2000 sources in the GeV
band. Here we report the performance of an Electron-Tracking Compton Camera
(ETCC), and prove that it has a good potential to break through this stagnation
in MeV gamma-ray astronomy. The ETCC provides all the parameters of
Compton-scattering by measuring 3-D recoil electron tracks; then the Scatter
Plane Deviation (SPD) lost in CCs is recovered. The energy loss rate (dE/dx),
which CCs cannot measure, is also obtained, and is found to be indeed helpful
to reduce the background under conditions similar to space. Accordingly the
significance in gamma detection is improved severalfold. On the other hand, SPD
is essential to determine the point-spread function (PSF) quantitatively. The
SPD resolution is improved close to the theoretical limit for multiple
scattering of recoil electrons. With such a well-determined PSF, we demonstrate
for the first time that it is possible to provide reliable sensitivity in
Compton imaging without utilizing an optimization algorithm. As such, this
study highlights the fundamental weak-points of CCs. In contrast we demonstrate
the possibility of ETCC reaching the sensitivity below erg
cm s at 1 MeV.Comment: 19 pages, 12 figures, Accepted to the Astrophysical Journa
Direct observation of mammalian cell growth and size regulation
We introduce a microfluidic system for simultaneously measuring single cell mass and cell cycle progression over multiple generations. We use this system to obtain over 1,000 hours of growth data from mouse lymphoblast and pro-B-cell lymphoid cell lines. Cell lineage analysis revealed a decrease in the growth rate variability at the G1/S phase transition, which suggests the presence of a growth rate threshold for maintaining size homeostasis
Significant effect of interfacial spin moments in ferromagnet-semiconductor heterojunctions on spin transport in a semiconductor
Using controlled ferromagnet (FM) -semiconductor (SC) interfaces in SC-based lateral spin-valve (LSV) devices, we experimentally study the effect of interfacial spin moments in FM-SC heterojunctions on spin transport in SC. First-principles calculations predict that the spin moment of FM-SC junctions can be artificially reduced by inserting 3d transition metal V, Cr, or Cu atomic layers between FM and SC. When all-epitaxial FM-SC Schottky-tunnel contacts with a 0.4-0.5-nm-thick V, Cr, or Cu interfacial layer are formed, we find that the spin signals in FM-SC LSV devices are significantly decreased at 8 K. When we increase the interfacial spin moment by inserting an ∼0.3-nm-thick Co layer between FM and SC, the spin signals at 8 K are significantly enhanced again. From these experiments, we conclude that the interfacial spin moments at FM-SC interfaces are one of the important factors to achieve large spin signals even in SC-based spintronic devices.T. Naito, R. Nishimura, M. Yamada, A. Masago, Y. Shiratsuchi, Y. Wagatsuma, K. Sawano, R. Nakatani, T. Oguchi, and K. Hamaya, Significant effect of interfacial spin moments in ferromagnet-semiconductor heterojunctions on spin transport in a semiconductor, Phys. Rev. B 105, 195308
Validation of U.S. mortality prediction models for hospitalised heart failure in the United Kingdom and Japan
Aims Prognostic models for hospitalized heart failure (HHF) were developed predominantly for patients of European origin in the United States of America; it is unclear whether they perform similarly in other health care systems or for different ethnicities. We sought to validate published prediction models for HHF in the United Kingdom (UK) and Japan. Methods and results Patients in the UK (n =894) and Japan (n =3158) were prospectively enrolled and were similar in terms of sex (∼60% men) and median age (∼77 years). Models predicted that British patients would have a higher mortality than Japanese, which was indeed true both for in‐hospital (4.8% vs. 2.5%) and 180‐day (20.7% vs. 9.5%) mortality. The model c‐statistics for the published/derivation (range 0.70–0.76) and Japanese (range 0.75–0.77) cohorts were similar and higher than for the UK (0.62–0.75) but models consistently overestimated mortality in Japan. For in‐hospital mortality, the OPTIMIZE‐HF model performed best, providing similar discrimination in published/derivation, UK and Japanese cohorts [c‐indices: 0.75 (0.74–0.77); 0.75 (0.68–0.81); and 0.77 (0.70–0.83), respectively], and least overestimated mortality in Japan. For 180‐day mortality, the c‐statistics for the ASCEND‐HF model were similar in published/derivation (0.70) and UK [0.69 (0.64–0.74)] cohorts but higher in Japan [0.75 (0.71–0.79)]; calibration was good in the UK but again overestimated mortality in Japan. Conclusion Calibration of published prediction models appears moderately accurate and unbiased when applied to British patients but consistently overestimates mortality in Japan. Identifying the reason why patients in Japan have a better than predicted prognosis is of great interest
The Origin of the Charge Ordering and Its Relevance to Superconductivity in -(BEDT-TTF)X: The Effect of the Fermi Surface Nesting and the Distant Electron-Electron Interactions
The origin of the charge ordering in organic compounds -(BEDT-TTF) ((SCN), Tl,Rb,Co, Cs,Zn) is studied using an extended
Hubbard model. Calculating the charge susceptibility within random phase
approximation (RPA), we find that the charge
ordering observed at relatively high temperatures can be considered as a
consequence of a cooperation between the Fermi surface nesting, controlled by
the hopping integral in the direction, and the electron-electron
interactions, where the distant (next nearest neighbor) interactions that have
not been taken into account in most of the previous studies play an important
role.Mean field analysis at T=0 also supports the RPA results, and further
shows that in the charge ordered state, some portions of the Fermi
surface remain ungapped and are nested with a nesting vector close to the
modulation wave vector of the horizontal stripe ordering observed at low
temperatures in (SCN). We further study the possibility of
superconductivity by taking into account the distant off-site repulsions and
the band structure corresponding to I, in which superconductivity is
experimentally observed. We find that there is a close competition between
-wave-like singlet pairing and -wave-like triplet pairing due
to a cooperation between the charge and the spin fluctuations. The present
analysis provides a possible unified understanding of the experimental phase
diagram of the -(BEDT-TTF) family, ranging from a charge ordered
insulator to a superconductor.Comment: 13 pages, 18 figures (Figs.5,6,7,14,15,18 compressed using jpeg2ps
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