(Carbonato-κ2 O,O′)bis­(1,10-phenan­throline-κ2 N,N′)cobalt(III) nitrate monohydrate

The crystal structure of the title compound, [Co(CO3)(C12H8N2)2]NO3·H2O, consists of CoIII complex cations, nitrate anions and uncoordinated water mol­ecules. The CoIII cation is chelated by a carbonate anion and two phenanthroline ligands in a distorted octa­hedral coordination geometry. A three-dimensional supra­molecular structure is formed by O—H⋯O and C—H⋯O hydrogen bonding, C—H⋯π and aromatic π–π stacking [centroid–centroid distance = 3.995 (1)Å] inter­actions

Synthesis, characterization and DFT-based investigation of a novel trinuclear singly-chloro-bridged copper(II)-1-vinylimidazole complex

Andac, Omer/0000-0003-3641-9690; Yolcu, Zuhal/0000-0001-7761-122XWOS: 000388256900024PubMed: 27640392A novel trinuclear copper(II) complex [Cu-3 (mu-Cl)(2) Cl-4 (1-Vim)(6)] with monodentate 1-vinylimidazole (1-Vim) and chloro ligands has been prepared and experimentally characterized by elemental analysis, thermogravimetry (TGA, DTG, DTA), X-ray single crystal diffractometry, TOF-MS and FT-IR spectroscopies. The electronic and structural properties of the complex were further investigated by DFT/TD-DFT methods. Density functional hybrid method (B3LYP) was applied throughout the calculations. The calculated UV-Vis results based on TD-DFT approach were simulated and compared with experimental spectrum. Based on the data obtained, DFT calculations have been found in reasonable accordance with experimental data

Development of MoS2 and Au nanoparticle including disposable CEA-based immuno-cytosensor platforms

In this study, an electrochemical biosensor for determination of Carcinoembryonic antigen (CEA) biomarker using human breast ductal adenocarcinoma (MCF-7) and human ovarian adenocarcinoma (SK-OV-3) cancer cells was presented. Disposable pencil graphite electrodes (PGE) has been modified with Au nanoparticle (Au NP) and MoS2 nanostructure dispersed chitosan (Cs) matrix. Therefore, the electrochemical interaction between the antibody-electrode surface was facilitated. Under optimal conditions, the immunosensor exhibited high sensitivity toward CEA biomarker in the low concentration range 0.01-10 ng mL(-1), with the detection limit of 1.93 ng mL(-1) and relative standard deviation of 4.65 (n = 5). The results indicated that even very small changes in CEA concentration can be sensed with the presented system. Also, recovery of the immunosensor found as 98 +/- 3% in the real sera samples containing dopamine and ascorbic acid. It has a great potential in the clinical screening of divergent cancer biomarkers. Experiments were conducted to determine the number of normal cell hGF and cancer cells adhered and attached on immuno-cytosensor surfaces. CEA-positive MCF-7 cells have shown great potential for adhesion and attachment to MoS2/Cs/Au/Anti-CEA/CEA surface better than CEA-negative cells. The developed immuno-cytosensor exhibited very promising results for the future biosensor studies

Synthesis, Crystal Structure, Spectroscopic and Thermal Properties of a Novel Complex of Hydantoin-5-acetic acid with Co(II)

Yolcu, Zuhal/0000-0001-7761-122X; TAS, MURAT/0000-0002-2879-6501WOS: 000317691200018The complex, tetraaqua bis(hydantoin-5-acetato) cobalt(II) was synthesized by the reaction of hydantoin-5-acetic acid and CoCl2 center dot 6H(2)O presence of NaHCO3. The structure of the complex was determined by X-Ray single crystal data the thermal analyses, FT-IR and magnetic susceptibility data are also presented. The monoclinic crystal of the title compound, [Co(C5H5N2O4)(2)(H2O)(4)], lie across centers of inversion in space group P21/c. The complex features a distorted octahedral [CoO6] coordination with hydantoin-5-acetato and water ligands. The hydantoin-5-acetato anion is bonded to the cobalt(II) ion via its deprotonated carboxylic acid O atom. The complex molecules show three dimensional supramolecular networks by O-H center dot center dot center dot O and N-H center dot center dot center dot O interactions