Evaluation of Hungarian Wines for Resveratrol by Overpressured Layer Chromatography

A method, including solid phase extraction sample preparation, overpressured layer chromatographic separation and subsequent densitometric evaluation, was developed for measurement of total resveratrol (cis- and trans-isomers) content of wine. The amount of resveratrol was determined in wine samples from different winemaking regions of Hungary. The total resveratrol was high in Hungarian red wines (3.6–11 mg/L), and much lower in white ones (0.04–1.5 mg/L)

Unpublished Mediterranean and Black Sea records of marine alien, cryptogenic, and neonative species

To enrich spatio-temporal information on the distribution of alien, cryptogenic, and neonative species in the Mediterranean and the Black Sea, a collective effort by 173 marine scientists was made to provide unpublished records and make them open access to the scientific community. Through this effort, we collected and harmonized a dataset of 12,649 records. It includes 247 taxa, of which 217 are Animalia, 25 Plantae and 5 Chromista, from 23 countries surrounding the Mediterranean and the Black Sea. Chordata was the most abundant taxonomic group, followed by Arthropoda, Mollusca, and Annelida. In terms of species records, Siganus luridus, Siganus rivulatus, Saurida lessepsianus, Pterois miles, Upeneus moluccensis, Charybdis (Archias) longicollis, and Caulerpa cylindracea were the most numerous. The temporal distribution of the records ranges from 1973 to 2022, with 44% of the records in 2020–2021. Lethrinus borbonicus is reported for the first time in the Mediterranean Sea, while Pomatoschistus quagga, Caulerpa cylindracea, Grateloupia turuturu, and Misophria pallida are first records for the Black Sea; Kapraunia schneideri is recorded for the second time in the Mediterranean and for the first time in Israel; Prionospio depauperata and Pseudonereis anomala are reported for the first time from the Sea of Marmara. Many first country records are also included, namely: Amathia verticillata (Montenegro), Ampithoe valida (Italy), Antithamnion amphigeneum (Greece), Clavelina oblonga (Tunisia and Slovenia), Dendostrea cf. folium (Syria), Epinephelus fasciatus (Tunisia), Ganonema farinosum (Montenegro), Macrorhynchia philippina (Tunisia), Marenzelleria neglecta (Romania), Paratapes textilis (Tunisia), and Botrylloides diegensis (Tunisia)

Ropivacaine spinal anesthesia is not antagonized by ondansetron pretreatment

BACKGROUND:: We investigated a possible effect of ondansetron on the duration of sensory and motor block produced by ropivacaine. METHODS:: Fifty male patients undergoing transurethral surgery received either 8 mg oral ondansetron the evening before surgery plus IV 8 mg ondansetron 15 min before subarachnoid anesthesia or placebo. All patients received 2.2 mL of 0.75% plain ropivacaine intrathecally. Sensory and motor block were assessed 30 min after the intrathecal injection and every 30 min thereafter until recovery from the motor block. RESULTS:: Thirty minutes after spinal injection of ropivacaine, we first measured, in both groups, the time to maximum block for both sensory and motor modalities. The maximum level of the sensory block, defined as decreased sensation, was T8 in the control and T6 in the ondansetron group, and absence of sensation was defined as T11 and T9 for the control and the ondansetron groups, respectively. Regarding block duration, 180 min after spinal injection, sensory block was detected in 11 of 22 and 16 of 24 patients and motor block in 1 of 22 and 0 of 24 in the control and ondansetron groups, respectively. Sensory and motor block did not differ between groups at any measured time point. CONCLUSIONS:: Ondansetron had no effect on the subarachnoid sensory or motor block produced by ropivacaine. Copyright © 2009 International Anesthesia Research Society

Relationship of Rainfall and Flood Return Periods through Hydrologic and Hydraulic Modeling

In order to examine the relationship between rainfall return periods and flood return periods, the design storm approach is compared to the rainfall–runoff continuous simulation and flood frequency analysis approach. The former was based on rainfall frequency analysis and event-based hydrological simulations, while the latter was based on continuous hydrological simulations and flood frequency analysis. All hydrological simulations were undertaken employing the HEC-HMS software. For the rainfall frequency analysis, the Generalized Extreme Value (GEV) probability distribution was used. For the flood frequency analysis, both the Extreme Value Type I (Gumbel) and GEV theoretical distributions were used and compared to each other. Flood hazard (inundation depth, flow velocities and flood extent) was estimated based on hydrodynamic simulations employing the HEC-RAS software. The study area was the Pineios catchment, upstream of Larissa city, Greece. The results revealed that the assumption of equivalent return periods of rainfall and discharge is not valid for the study area. For instance, a 50-year return period flood corresponds to a rainfall return period of about 110 years. Even if flow measurements are not available, continuous simulation based on re-analysis datasets and flood frequency analysis may be alternatively used

Relationship of Rainfall and Flood Return Periods through Hydrologic and Hydraulic Modeling

In order to examine the relationship between rainfall return periods and flood return periods, the design storm approach is compared to the rainfall–runoff continuous simulation and flood frequency analysis approach. The former was based on rainfall frequency analysis and event-based hydrological simulations, while the latter was based on continuous hydrological simulations and flood frequency analysis. All hydrological simulations were undertaken employing the HEC-HMS software. For the rainfall frequency analysis, the Generalized Extreme Value (GEV) probability distribution was used. For the flood frequency analysis, both the Extreme Value Type I (Gumbel) and GEV theoretical distributions were used and compared to each other. Flood hazard (inundation depth, flow velocities and flood extent) was estimated based on hydrodynamic simulations employing the HEC-RAS software. The study area was the Pineios catchment, upstream of Larissa city, Greece. The results revealed that the assumption of equivalent return periods of rainfall and discharge is not valid for the study area. For instance, a 50-year return period flood corresponds to a rainfall return period of about 110 years. Even if flow measurements are not available, continuous simulation based on re-analysis datasets and flood frequency analysis may be alternatively used

Predictors of mortality of trauma patients admitted to the ICU: a retrospective observational study☆.

Worldwide, trauma is one of the leading causes of morbidity and mortality. The aim of the present study is to identify the predictors of mortality of trauma patients requiring Intensive Care Unit (ICU) admission. This retrospective study was conducted in the ICU of our institution in Greece during a six-year period (2010-215). Among 326 patients, trauma was caused by road traffic accidents in .5%, followed by falls (21.1%) and violence (7.4%). Thirty-day mortality was 27.3%. Multivariate analysis showed that higher New Injury Severity Score (NISS), severe head/neck injury, acute kidney injury, septic shock and hemorrhagic shock were significantly associated with mortality while higher Revised Injury Severity Classification, version II (RISC II) and the administration of enteral nutrition were associated with survival. NISS showed the higher accuracy in predicting 30-day mortality followed by RISC II, while scores based only in physiological variables had lower predictive ability. Increased mortality was strongly associated with the severity of the injury upon admission. Traumatic brain injury, septic shock and acute kidney injury have also been found among the strongest predictors of mortality. NISS can be considered as a statistically superior score in predicting mortality of severely injured patients

Fatores de risco para mortalidade após hemorragia subaracnoidea: estudo observacional retrospectivo [Risk factors for mortality after subarachnoid hemorrhage: a retrospective observational study]

Subarachnoid haemorrhage is an important cause of morbidity and mortality. The aim of the study was to determine predictors of mortality among patients with subarachnoid hemorrhage hospitalized in an Intensive Care Unit. This is a retrospective study of patients with subarachnoid hemorrhage admitted to the Intensive Care Unit of our institution during a 7 year period (2009-2015). Data were collected from the Intensive Care Unit computerized database and the patients' chart reviews. We included in the study 107 patients with subarachnoid haemorrhage. A ruptured aneurysm was the cause of subarachnoid haemorrhage in 76 (71%) patients. The overall mortality was 40% (43 patients), and was significantly associated with septic shock, midline shift on CT scan, inter-hospital transfer, aspiration pneumonia and hypernatraemia during the first 72 hours of Intensive Care Unit stay. Multivariate analysis of patients with subarachnoid hemorrhage following an aneurysm rupture revealed that mortality was significantly associated with septic shock and hypernatremia during the first 72 hours of Intensive Care Unit stay, while early treatment of aneurysm (clipping or endovascular coiling) within the first 72 hours was identified as a predictor of a good prognosis. Transferred patients with subarachnoid haemorrhage had lower survival rates. Septic shock and hypernatraemia were important complications among critically ill patients with subarachnoid haemorrhage and were associated increased mortality

Association between bone scintigraphy features of spinal degeneration and anthropometric and demographic variables

BACKGROUND AND OBJECTIVES: Bone scintigraphy is a molecular imaging technique routinely used for the evaluation of benign and malignant bone abnormalities. This study aimed at evaluating spinal degenerative changes detected by bone scintigraphy and determining associations between image features and patients' anthropometric and demographic variables. MATERIAL AND METHOD: In a cross-sectional study, 64 men and 52 women underwent bone scintigraphy. Experts identified all image regions suggesting degenerative joint disease (DJD) and classified region intensity on a 3-point scale. Image characteristics were correlated to the patients' body mass index (BMI), age, weight, height, activity level, and sex. Data analysis included descriptive statistics and association coefficients. RESULTS: DJD was found in 53 patients (46%). In men, there was weak but statistically significant correlation between DJD and activity level, and DJD and age, but not BMI or weight. In women, only a weak, not statistically significant, linear correlation was found between DJD and BMI, and DJD and weight. CONCLUSION: Molecular imaging with bone scintigraphy showed that spinal degenerations are associated with different anthropometric and demographic features in men and women. Interestingly, no association was found between DJD and increased body weight in men while a weak association may exist in women. The results prompt for additional studies to better determine the risk factors for DJD and low back pain in male and female patients. LEVEL OF EVIDENCE: Diagnostic study, Level II (retrospective study). © 2015-IOS Press and the authors