162 research outputs found
Florida Institute of Technology Ordered to Reinstate Men\u27s Rowing after Title IX Complaint
In February 2023, the U.S. District Court in Florida issued a preliminary injunction in favor of six male student-athletes from Florida Institute of Technology who alleged that the university violated Title IX. The male student-athletes filed the lawsuit against Florida Institute of Technology (FIT) in 2022. The student-athletes claimed FIT violated Title IX when the university eliminated rowing and other programs
Title IX at 50: Exploring the Impact of the Law on Cases of Sexual Misconduct and Participation Equity in Athletics
June 23, 2022 will mark the 50th anniversary of Title IX; during that time frame there has been a drastic increase in girlâs and womenâs participation in sport. There has also been signiïŹcant political debate and push back to Title IX which has threatened to undermine the impact of the law. Over the last 10 years, Title IX has been synonymous with litigation related to sexual harassment and transgender athlete participation in sport. Additionally, universities have continually sought to cut womenâs sports under the guise of budgetary constraints. The purpose of this poster presentation is three-fold: 1) Review recent case developments in terms of cutting womenâs sports; 2) emphasize that procedurally, sexual harassment and misconduct claims are in ïŹux across campuses; and 3) discuss the current state of transgender athlete participation policies in sports
Terminated ASU Women\u27s Lacrosse Coach Files Retaliation and Wrongful Termination Lawsuit
Courtney Connor, the former womenâs lacrosse coach at Arizona State University, sued the University and the Arizona Board of Regents (collectively, âASUâ) for Title VII and Title IX retaliation, as well as wrongful termination
College Student Perceptions of Professional Development Through Sport Management Club Participation
Background Literature
Traditionally, college students engaged in learning within the classroom setting. Research indicates that students can also learn in extracurricular activities such as internships and student clubs (Brown & Johnson, 2018). While research in the field of sport management has focused on the role of internships in professional development (e.g. Hayes & Mudrick, 2018; Young & Baker, 2004), less research has focused on the role of sport management clubs and how club participation may enhance a club memberâs professional development. In addition, little research has focused on barriers that prevent students from joining.
Purpose
The purpose of this study was to examine student perceptions of the role that sport management clubs play in their professional development and barriers students face in joining those clubs.
Research question What skills do students think sport management clubs help them build? What barriers prevent students from joining sport management clubs
Sport Management Clubs and Their Relationship to Sport Management Student Success
Participation in student-led sport management clubs can be beneficial for college students who are pursing sport management careers. These clubs can help give students the development and networking tools needed for success in the sport industry.
The purpose of this presentation is to discuss the role and benefits of sport management clubs at three universities across three NCAA divisions, with a focus on networking, fundraising, event planning, and professional development.
Our discussion will also include specific events that our students have completed as well as how the clubs provide students with opportunities to develop the skills and abilities to succeed in the sport industry
Preferences and priorities for relapsed multiple myeloma treatments among patients and caregivers in the United States
Introduction/Background: This study aimed to describe patient and caregiver preferences for treatments of relapsed or refractory multiple myeloma (MM).
Materials and Methods: A survey including discrete-choice experiment (DCE) and best-worst scaling (BWS) exercises was conducted among US patients with relapsed or refractory MM and their caregivers. The DCE included six attributes with varying levels including progression-free survival (PFS), toxicity, and mode and frequency of administration. In addition, the impact of treatment cost was assessed using a fixed-choice question. The BWS exercise included 18 items (modes and frequency of administration, additional treatment convenience, and toxicity items). The survey was administered online to patients recruited from the Multiple Myeloma Research Foundation CoMMpass study (NCT01454297).
Results: The final samples consisted of 94 patients and 32 caregivers. Avoiding severe nerve damage was most important to patients, followed by longer PFS. Caregivers considered PFS to be the most important attribute. We estimate that a third or more of patients were cost-sensitive, meaning their treatment preference was altered based on cost implications. Caregivers were not cost-sensitive. The three most bothersome treatment features in the BWS exercise were risk of kidney failure, lowering white blood cell counts, and weakening the immune system.
Conclusion: Patients with relapsed or refractory MM and their caregivers consider many factors including efficacy, toxicity, mode/frequency of administration, and cost in their decisions regarding treatment options. The study provides a basis for future Research on patient and caregiver treatment preferences, which could be incorporated into shared decision-making with physicians
International Myeloma Workshop Consensus Panel 1. Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1
Birtamimab plus standard of care in light-chain amyloidosis: the phase 3 randomized placebo-controlled VITAL trial
Amyloid light-chain (AL) amyloidosis is a rare, typically fatal disease characterized by the accumulation of misfolded immunoglobulin light chains (LCs). Birtamimab is an investigational humanized monoclonal antibody designed to neutralize toxic LC aggregates and deplete insoluble organ-deposited amyloid via macrophage-induced phagocytosis. VITAL was a phase 3 randomized, double-blind, placebo-controlled clinical trial assessing the efficacy and safety of birtamimab + standard of care (SOC) in 260 newly diagnosed, treatment-naive patients with AL amyloidosis. Patients received 24 mg/kg IV birtamimab + SOC or placebo + SOC every 28 days. The primary composite end point was the time to all-cause mortality (ACM) or centrally adjudicated cardiac hospitalization â„91 days after the first study drug infusion. The trial was terminated early after an interim futility analysis; there was no significant difference in the primary composite end point (hazard ratio [HR], 0.826; 95% confidence interval [CI], 0.574-1.189; log-rank P = .303). A post hoc analysis of patients with Mayo stage IV AL amyloidosis, those at the highest risk of early mortality, showed significant improvement in the time to ACM with birtamimab at month 9 (HR, 0.413; 95% CI, 0.191-0.895; log-rank P = .021). At month 9, 74% of patients with Mayo stage IV AL amyloidosis treated with birtamimab and 49% of those given placebo survived. Overall, the rates of treatment-emergent adverse events (TEAEs) and serious TEAEs were generally similar between treatment arms. A confirmatory phase 3 randomized, double-blind, placebo-controlled clinical trial of birtamimab in patients with Mayo stage IV AL amyloidosis (AFFIRM-AL; NCT04973137) is currently enrolling. The VITAL trial was registered at www.clinicaltrials.gov as #NCT02312206
Phase 1 study of selinexor plus carfilzomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/150566/1/bjh15969.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/150566/2/bjh15969_am.pd
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