64 research outputs found
A Novel Scholar Embedding Model for Interdisciplinary Collaboration
Interdisciplinary collaboration has become a driving force for scientific
breakthroughs, and evaluating scholars' performance in interdisciplinary
researches is essential for promoting such collaborations.However, traditional
scholar evaluation methods based solely on individual achievements do not
consider interdisciplinary cooperation, creating a challenge for
interdisciplinary scholar evaluation and recommendation. To address this issue,
we propose a scholar embedding model that quantifies and represents scholars
based on global semantic information and social influence, enabling real-time
tracking of scholars' research trends. Our model incorporates semantic
information and social influence for interdisciplinary scholar evaluation,
laying the foundation for future interdisciplinary collaboration discovery and
recommendation projects. We demonstrate the effectiveness of our model on a
sample of scholars from the Beijing University of Posts and Telecommunications.Comment: 9 pages, 4 figures, 1 tabl
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Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics.
Our knowledge of transcriptional heterogeneities in epithelial stem and progenitor cell compartments is limited. Epidermal basal cells sustain cutaneous tissue maintenance and drive wound healing. Previous studies have probed basal cell heterogeneity in stem and progenitor potential, but a comprehensive dissection of basal cell dynamics during differentiation is lacking. Using single-cell RNA sequencing coupled with RNAScope and fluorescence lifetime imaging, we identify three non-proliferative and one proliferative basal cell state in homeostatic skin that differ in metabolic preference and become spatially partitioned during wound re-epithelialization. Pseudotemporal trajectory and RNA velocity analyses predict a quasi-linear differentiation hierarchy where basal cells progress from Col17a1Hi/Trp63Hi state to early-response state, proliferate at the juncture of these two states, or become growth arrested before differentiating into spinous cells. Wound healing induces plasticity manifested by dynamic basal-spinous interconversions at multiple basal transcriptional states. Our study provides a systematic view of epidermal cellular dynamics, supporting a revised "hierarchical-lineage" model of homeostasis
PowerFusion: A Tensor Compiler with Explicit Data Movement Description and Instruction-level Graph IR
Deep neural networks (DNNs) are of critical use in different domains. To
accelerate DNN computation, tensor compilers are proposed to generate efficient
code on different domain-specific accelerators. Existing tensor compilers
mainly focus on optimizing computation efficiency. However, memory access is
becoming a key performance bottleneck because the computational performance of
accelerators is increasing much faster than memory performance. The lack of
direct description of memory access and data dependence in current tensor
compilers' intermediate representation (IR) brings significant challenges to
generate memory-efficient code.
In this paper, we propose IntelliGen, a tensor compiler that can generate
high-performance code for memory-intensive operators by considering both
computation and data movement optimizations. IntelliGen represent a DNN program
using GIR, which includes primitives indicating its computation, data movement,
and parallel strategies. This information will be further composed as an
instruction-level dataflow graph to perform holistic optimizations by searching
different memory access patterns and computation operations, and generating
memory-efficient code on different hardware. We evaluate IntelliGen on NVIDIA
GPU, AMD GPU, and Cambricon MLU, showing speedup up to 1.97x, 2.93x, and
16.91x(1.28x, 1.23x, and 2.31x on average), respectively, compared to current
most performant frameworks.Comment: 12 pages, 14 figure
Quench of a Single-Layer ReBCO CORC Cable with Non-Uniform Terminal Contact Resistance
ReBCO conductor-on-round-core (CORC) cable has become a promising candidate for high temperature superconducting (HTS) power applications, due to its great mechanical strength, high current carrying capacity, high flexibility, and low ac losses. However, ReBCO coated conductors are at risk of quenching, which significantly affects the thermal stability and reliability of the CORC cable. Three-dimensional (3-D) numerical study on the quench behavior of the CORC cable remains a challenge, for its complex geometry is difficult to cope with. In this paper, a 3-D time-dependent multi-physics quench model based on the T-A formulation has been developed. Three modules are coupled in this model; the T-A formulation model, a heat transfer model, and an equivalent circuit model. The quench behavior of a single-layer ReBCO CORC cable with non-uniform terminal contact resistances has been studied, when a hotspot is imposed on one of the tapes to induce a local quench. Results show that, the CORC cable has the highest MQE; in other words, it is the most stable situation, when the hotspot-induced quench occurs on the tape with the middle value of terminal contact resistance
Quantitative analysis of guided wave in dielectric logging through numerical simulation
A good knowledge of the electromagnetic (EM) wave propagation behaviors in dielectric logging (DL) and borehole radar (BHR) surveying is critically important for the optimization of tool design and implementation, and interpretation of the acquired logging data, as well as understanding the influences of the dielectric permittivity and conductivity of the formation on the EM waves. This letter reported a novel method for the numerical simulation and analysis of the guided wave (GW) propagating along a metallic pipe in a typical DL configuration. A numerical simulation with the 3-D finite-difference time-domain (FDTD) method was applied to the broadband DL tool to obtain the wavefield and responses of the receiver. By monitoring the wave attenuation along the metallic drill collar, the intensity of the GW and loss factor can be determined. The coupling efficiency of the GW can be obtained when the total power emitted from the transmitting antenna is known. Simulation results revealed that the coupling efficiency of the GW changes with the water saturation of the formation and frequency. The simulation also suggest, by installing a slope structure adjacent to the transmitting antenna, the energy coupled into the GW could be reduced at different levels. Finally, the relationship between the received signals' amplitude and GW's coupling efficiency showed the quantified contribution of the GW to the received sign
Milestones in autonomous driving and intelligent vehicles: survey of surveys
Interest in autonomous driving (AD) and intelligent vehicles (IVs) is growing at a rapid pace due to the convenience, safety, and economic benefits. Although a number of surveys have reviewed research achievements in this field, they are still limited in specific tasks, lack of systematic summary and research directions in the future. Here we propose a Survey of Surveys (SoS) for total technologies of AD and IVs that reviews the history, summarizes the milestones, and provides the perspectives, ethics, and future research directions. To our knowledge, this article is the first SoS with milestones in AD and IVs, which constitutes our complete research work together with two other technical surveys. We anticipate that this article will bring novel and diverse insights to researchers and abecedarians, and serve as a bridge between past and future
Robust estimation of bacterial cell count from optical density
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
Quench of a Single-Layer ReBCO CORC Cable with Non-Uniform Terminal Contact Resistance
ReBCO conductor-on-round-core (CORC) cable has become a promising candidate for high temperature superconducting (HTS) power applications, due to its great mechanical strength, high current carrying capacity, high flexibility, and low ac losses. However, ReBCO coated conductors are at risk of quenching, which significantly affects the thermal stability and reliability of the CORC cable. Three-dimensional (3-D) numerical study on the quench behavior of the CORC cable remains a challenge, for its complex geometry is difficult to cope with. In this paper, a 3-D time-dependent multi-physics quench model based on the T-A formulation has been developed. Three modules are coupled in this model; the T-A formulation model, a heat transfer model, and an equivalent circuit model. The quench behavior of a single-layer ReBCO CORC cable with non-uniform terminal contact resistances has been studied, when a hotspot is imposed on one of the tapes to induce a local quench. Results show that, the CORC cable has the highest MQE; in other words, it is the most stable situation, when the hotspot-induced quench occurs on the tape with the middle value of terminal contact resistance.</p
The Impact of Urban Construction Land Expansion on Carbon Emissions from the Perspective of the Yangtze River Delta Integration, China
Regional integration plays a pivotal role in the socio-economic advancement of various global regions and is closely linked with the expansion of construction land. This expansion is a major contributor to urban carbon emissions. Utilizing a geographical regression discontinuity design (GRDD), this paper estimates the impact of urban construction land expansion on carbon emissions and explores the underlying mechanisms within the regional integration process of the Yangtze River Delta (YRD), China. The findings reveal that urban construction land expansion significantly influences carbon emissions, displaying an inverted “U”-shaped pattern. Furthermore, this expansion affects carbon emissions through the transformation of industrial structures, shifts in consumption patterns, and enhancements in scientific and technological investments. Our findings span the performance of the Yangtze River Delta from its early development stages to a relatively mature phase. This paper also partially reveals how the Yangtze River Delta, with both megacities and large- to medium-sized cities, manages urban construction land expansion during the integration process and strives for low-carbon emissions reduction. These results can provide green growth recommendations that balance socio-economic development, low-carbon emissions, and social equity not only for other urban agglomerations in China but also for similar regions in other developing countries by altering construction land utilization patterns
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