Horizontal mantle flow controls subduction dynamics

It is generally accepted that subduction is driven by downgoing-plate negative buoyancy. Yet plate age –the main control on buoyancy– exhibits little correlation with most of the present-day subduction velocities and slab dips. “West”-directed subduction zones are on average steeper (~65°) than “East”-directed (~27°). Also, a “westerly”-directed net rotation of the lithosphere relative to the mantle has been detected in the hotspot reference frame. Thus, the existence of an “easterly”-directed horizontal mantle wind could explain this subduction asymmetry, favouring steepening or lifting of slab dip angles. Here we test this hypothesis using high-resolution two-dimensional numerical thermomechanical models of oceanic plate subduction interacting with a mantle flow. Results show that when subduction polarity is opposite to that of the mantle flow, the descending slab dips subvertically and the hinge retreats, thus leading to the development of a back-arc basin. In contrast, concordance between mantle flow and subduction polarity results in shallow dipping subduction, hinge advance and pronounced topography of the overriding plate, regardless of their age-dependent negative buoyancy. Our results are consistent with seismicity data and tomographic images of subduction zones. Thus, our models may explain why subduction asymmetry is a common feature of convergent margins on Earth

Measurements of hyperfine structure in Ta II

We report the first extensive measurements of hyperfine structure in Ta II. Spectra of Ta II were recorded by high-resolution Fourier transform spectrometry in the region 10 000-53 000 cm-1(1886-10 000 Å) and the majority of observed lines show significant hyperfine structure. Computer fits to several hundred of these line profiles have yielded values of the magnetic dipole hyperfine interaction constant A for 88 energy levels with an uncertainty of between 0.5 and 10 per cent for the majority of A factors. The A factors range from −0.078 to +0.065 cm−1 for the even levels and from −0.064 to +0.083 cm−1 for the odd levels. For the majority of these A factors no previous measurements are known. Approximate values of the electric quadrupole hyperfine interaction constant B were found for 73 levels. These measurements of A and B factors allow, for the first time, the effects of hyperfine structure in Ta II lines to be correctly accounted for both in abundance analysis and in the resolution of blended lines in astrophysical spectr

Fecal N excretion as an approach to estimate forage intake by sheep and cattle.

This study was carried out to evaluate the reliability of using faecal N as a predictor of organic matter (OM) intake by sheep and cattle fed a natural pasture hay

Comparison of metabolic, oxidative and inflammatory status of Simmental × Holstein crossbred with parental breeds during the peripartal and early lactation periods.

AbstractThe aim of the research reported in this paper was to evaluate plasma concentrations of energy, oxidative and inflammatory biomarkers of Simmental (sire) × Holstein (dam) crossbred cows, in comparison with the two parental breeds during the peripartal and early lactation periods and to estimate the effects of heterosis for these traits. Thirty-three animals, managed under the same conditions, 8 Simmental (SI), 9 Holstein (HO) and 16 crossbred (CR) cows were enrolled in this study. Glucose, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), total bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatine kinase (CK), total protein, albumin, creatinine and urea were determined in blood sampled at six different time points (30 ± 3 and 15 ± 3 d before the expected calving date, at calving and 15, 30 and 60 d after calving). Furthermore, derived reactive oxygen metabolites (d-ROMs), biological antioxidant potential (BAP), interleukin-6 (IL-6), haptoglobin (Hp) and serum amyloid A protein (SAA) were determined to evaluate inflammatory and oxidative status. Results showed that the CR group had significantly lower average values of glucose and NEFA when compared to HO group; signifcantly lower values of urea than SI group and significantly higher values of creatinine than HO. Furthermore, CR cows showed the lowest average value of d-ROMs with respect to SI and HO parental breeds. Finally, the average value of haptoglobin was significantly lower in CR and HO groups, when compared to SI group. As for the heterosis we found the highest (positive) percentage for CK (98%) and BAP (47%) and the lowest (negative) percentage for OSi (−75%) and d-ROMs (−39%). A negative percentage was also found for the glucose (−11%) and NEFA (−20%) toward the Simmental parental breed. Our results suggest a different response among the three genetic groups during the peripartal and early lactation periods. In particular, CR and SI cows seem more adaptable regarding energy metabolism and oxidative status. Heterosis led to a positive effect on those parameters in Simmental (sire) × Holstein (dam) crossbred cows F1 population (50% Simmental and 50% Holstein)

RNA aptamers specific for transmembrane p24 trafficking protein 6 and Clusterin for the targeted delivery of imaging reagents and RNA therapeutics to human β cells

The ability to detect and target β cells in vivo can substantially refine how diabetes is studied and treated. However, the lack of specific probes still hampers a precise characterization of human β cell mass and the delivery of therapeutics in clinical settings. Here, we report the identification of two RNA aptamers that specifically and selectively recognize mouse and human β cells. The putative targets of the two aptamers are transmembrane p24 trafficking protein 6 (TMED6) and clusterin (CLUS). When given systemically in immune deficient mice, these aptamers recognize the human islet graft producing a fluorescent signal proportional to the number of human islets transplanted. These aptamers cross-react with endogenous mouse β cells and allow monitoring the rejection of mouse islet allografts. Finally, once conjugated to saRNA specific for X-linked inhibitor of apoptosis (XIAP), they can efficiently transfect non-dissociated human islets, prevent early graft loss, and improve the efficacy of human islet transplantation in immunodeficient in mice

Real-Time Treatment Planning Optimisation for Brachytherapy

In this paper, we present an integrated system for real-time dose distribution calculation and treatment planning optimisation for brachytherapy of prostate cancer, with a special emphasis on the visual integration of the dosimetry and target images obtained from the open magnetic resonance system. This system involves a fast method to calculate dose distributions of multiple concurrent radioactive sources, based on the combination of elements from a database of pre-calculated dose distribution maps for single sources, combined linearly to provide the final dose distribution map. Simulated annealing, in conjunction with the inverse planning method, is used to determine the source dwell times at pre-selected locations in order to optimally irradiate thetumour while preserving the surrounding healthy tissues. This algorithm, implemented in FORTRAN, is integrated into a computer-assisted treatment planning tool, written in JAVA, using the runtime class and RMI API of Java. The whole system is now under clinical testing at the Geneva University Hospital

Zno thin films growth optimization for piezoelectric application

The piezoelectric response of ZnO thin films in heterostructure-based devices is strictly related to their structure and morphology. We optimize the fabrication of piezoelectric ZnO to reduce its surface roughness, improving the crystalline quality, taking into consideration the role of the metal electrode underneath. The role of thermal treatments, as well as sputtering gas composition, is investigated by means of atomic force microscopy and x-ray diffraction. The results show an optimal reduction in surface roughness and at the same time a good crystalline quality when 75% O2 is introduced in the sputtering gas and deposition is performed between room temperature and 573 K. Subsequent annealing at 773 K further improves the film quality. The introduction of Ti or Pt as bottom electrode maintains a good surface and crystalline quality. By means of piezoelectric force microscope, we prove a piezoelectric response of the film in accordance with the literature, in spite of the low ZnO thickness and the reduced grain size, with a unipolar orientation and homogenous displacement when deposited on Ti electrode

A novel free-electron laser single-pulse Wollaston polarimeter for magneto-dynamical studies

Here, we report on the conceptual design, the hardware realization, and the first experimental results of a novel and compact x-ray polarimeter capable of a single-pulse linear polarization angle detection in the extreme ultraviolet photon energy range. The polarimeter is tested by performing time resolved pump-probe experiments on a Ni80Fe20 Permalloy film at the M-2,M-3 Ni edge at an externally seeded free-electron laser source. Comparison with similar experiments reported in the literature shows the advantages of our approach also in view of future experiments

Avaliação de atributos físico-químicos e sensoriais de sucos de uva elaborados com nove cultivares de uva.

XV Congresso Latino-Americano de Viticultura e Enologia E XIII Congresso Brasileiro de Viticultura e Enologia. Bento Gonçalves-RS, 3 a 7 de Novembro de 2015