Application of Constructivist Theory in Flipped Classroom — Take College English Teaching as a Case Study

In the context of information globalization and the popularity of the Internet, the flipped classroom as a new teaching mode, a new pedagogical method has become a heated topic and a growing concern for educators across the world. In this paper, the flipped classroom is supported by constructivist learning theory. The teaching mode under the constructivist learning theory is typically students-centered which corresponds with the flipped classroom mode. This paper mainly focuses on the application of constructivist learning theory in flipped classroom, taking college English teaching for example to interpret the student- student, teacher- student interactions in the flipped classroom with the final goal to promote students’ learning efficiency and quality

Amor de Perdição – Uma Análise de Tradução Português – Chinês

O presente trabalho analisa a tradução de Amor de Perdição, obra de Camilo Castelo Branco, traduzida por Wang Suoying, que é, até à data, a mais recente tradução para chinês deste romance. Camilo Castelo Branco foi um escritor português do século XIX, com um vasto conjunto de obras, nas quais transparecem a sua vivência dramática, a angústia e a sociedade do seu tempo. A narrativa e alguns temas de Amor de Perdição traz aos leitores chineses um romance clássico do panorama literário português, com um paralelismo interessante com o clássico da literatura chinesa O Sonho do Pavilhão vermelho de Cao Xueqin do século XVIII. A análise da tradução antroponímica, da tradução da retórica, da utilização de “chengyu” e da tradução de provérbios foi feita neste trabalho. Foi verificado na tradução antroponímica a preferência por nomes traduzidos que correspondam aos costumes dos nomes chineses. Na tradução da retórica, verificou-se a aplicação da tradução literal dos recursos estilístico, mas também o uso de provérbios ou expressões idiomáticas equivalentes. Uma tradução apresenta inevitavelmente tendências de deformação. Foram analisadas e exemplificadas as tendências de deformação presentes na tradução de Wang Suoying, como tendências de expansão, de enobrecimento, de destruição de ritmo e do vernáculo, de clarificação e de empobrecimento qualitativo e quantitativo. Por fim foram também discutidos outros casos de distanciamento face ao texto de partida relativos a esta versão de tradução como potenciais melhorias.This thesis analyzes the translation of Amor de Perdição, a novel by Camilo Castelo Branco, translated by Wang Suoying, which is, to this date, the most recent Chinese translation of this novel. Camilo Castelo Branco was a Portuguese writer of the nineteenth century, with a wide range of works, in which his dramatic life, anguish, and the society of his time shine through. The narrative and some contents of Amor de Perdição brings to the Chinese readers a classic novel of the Portuguese literary landscape with an interesting parallelism with the classic of the Chinese literature The Dream of the Red Chamber by Cao Xueqin of the eighteenth century. The analysis of anthroponomic translation, rhetoric translation, the use of “chengyu” and the translation of proverbs was done in this thesis. It was found that in anthroponomic translation there is preference for translated names that correspond to the habit of Chinese names. In translation of rhetoric, we can see the use of literal translation of stylistic resources, but also the use of proverbs or equivalent idioms. A translation inevitably presents deformation tendencies. The deformation tendencies present in the translation of Wang Suoying were analyzed and exemplified, such as tendencies of expansion, ennoblement, destruction of rhythm and vernacular, clarification and qualitative and quantitative impoverishment. Finally, other cases of divergence from the source language concerning this version of translation were also discussed as potential improvements

Cellular immunotherapy as maintenance therapy prolongs the survival of the patients with small cell lung cancer in extensive stage

AbstractBackgroundSmall cell lung cancer (SCLC) is the most devastating type of human lung cancer. Patients usually present with disseminated disease to many organs (extensive stage). This study was to investigate the efficacy and safety of cellular immunotherapy (CIT) with autologous natural killer (NK), γδT, and cytokine-induced killer (CIK) cells as maintenance therapy for extensive-stage SCLC (ES-SCLC) patients.MethodsA pilot prospective cohort study was conducted with ES-SCLC patients who had responded to initial chemotherapy. Patients received either CIT as maintenance therapy (CIT group), or no treatment (control group). Progression-free survival (PFS), overall survival (OS), and adverse effects were compared.ResultsForty-nine patients were recruited in this study, with 19 patients in the CIT group and 30 patients in the control group. The patient characteristics of the 2 groups were comparable except for age, as patients in the CIT group were older than those in the control group (P < 0.05). PFS in the CIT group was superior to the control group (5 vs. 3.1 months, P = 0.020; HR, 0.489, 95% CI, 0.264–0.909, P = 0.024). OS of the CIT group was also longer than that of the control group (13.3 vs. 8.2 months, P = 0.044; HR, 0.528, 95% CI, 0.280–0.996, P = 0.048, respectively). No significant adverse reactions occurred in patients undergoing CIT.ConclusionsCIT maintenance therapy in ES-SCLC prolonged survival with only minimal side effects. Integrating CIT into the current treatment may be a novel strategy for ES-SCLC patients, although further multi-center randomized trials are needed

Propeller: A Scalable Real-Time File-Search Service in Distributed Systems

File-search service is a valuable facility to accelerate many analytics applications, because it can drastically reduce the scale of the input data. The main challenge facing the design of large-scale and accurate file-search services is how to support real-time indexing in an efficient and scalable way. To address this challenge, we propose a distributed file-search service, called Propeller, which utilizes a special file-access pattern, called access-causality, to partition file-indices in order to expose substantial access locality and parallelism to accelerate the file-indexing process. The extensive evaluations of Propeller show that it is realtime in file-indexing operations, accurate in file-search results, and scalable in large datasets. It achieves significantly better file-indexing and file-search performance (up to 250×) than a centralized solution (MySQL) and much higher accuracy and substantially lower query latency (up to 22×) than a state-ofthe- art desktop search engine (Spotlight)

Providing Flexible File-Level Data Filtering for Big Data Analytics

The enormous amount of big data datasets impose the needs for effective data filtering technique to accelerate the analytics process. We propose a Versatile Searchable File System, VSFS, which provides a transparent, flexible and near real-time file-level data filtering service by searching files directly through the file system. Therefore, big data analytics applications can transparently utilize this filtering service without application modifications. A versatile index scheme is designed to adapt to the exploratory and ad-hoc nature of the big data analytics activities. Moreover, VSFS uses a RAM-based distributed architecture to perform file indexing. The evaluations driven by three real-world analytics applications demonstrate VSFS’ high scalability and data-filtering capability

VSFS: A Versatile Searchable File System for HPC Analytics

Big-data/HPC analytics applications have urgent needs for file-search services to drastically reduce the scale of the input data to accelerate analytics. Unfortunately, the existing solutions either are poorly scalable for large-scale systems, or lack well-integrated interface to allow applications to easily use them. We propose a distributed searchable file system, VSFS, which provide a novel and flexible POSIX-compatible searchable file system namespace that can be seamlessly integrate with any legacy code without modification. Additionally, to provide real-time indexing and searching performance, VSFS uses DRAM-based distributed consistent hashing ring to manages all file-index. The results of our evaluation show that VSFS is scalable in HPC environment. It achieves significant better file-indexing and file-searching performance than the popular SQL/NoSQL solutions, while it only introduces negligible overheads to raw I/O performance. Finally, we integrate the VSFS to a scientific analytic application to show its benefits in terms of performance and convenience

Media Bias and Factors Affecting the Impartiality of News Agencies during COVID-19

When COVID-19 was raging around the world, people were more fearful and anxious. In this context, the media should uphold impartiality and shoulder the responsibility of eliminating misinformation. Therefore, our research adopted sentiment analysis technologies to analyze the impartiality of news agencies and analyzed the factors that affect the impartiality of COVID-19-related articles about various countries. The SentiWordNet3.0 and bidirectional encoder representations from transformers (BERT) models were employed to analyze the articles and visualize the data. The following conclusions were redrawn in our research. During the pandemic, articles of some news agencies were not objective; the impartiality of news agencies was related to the reliability of news agencies instead of the bias of news agencies; there were obvious differences in the coverage and positivity of international news agencies to report the performance of COVID-19 prevention and control in different countries

Ferroptosis: A Double-Edged Sword in Gastrointestinal Disease

Ferroptosis is a novel form of regulated cell death (RCD) that is typically accompanied by iron accumulation and lipid peroxidation. In contrast to apoptosis, autophagy, and necroptosis, ferroptosis has unique biological processes and pathophysiological characteristics. Since it was first proposed in 2012, ferroptosis has attracted attention worldwide. Ferroptosis is involved in the progression of multiple diseases and could be a novel therapeutic target in the future. Recently, tremendous progress has been made regarding ferroptosis and gastrointestinal diseases, including intestinal ischemia/reperfusion (I/R) injury, inflammatory bowel disease (IBD), gastric cancer (GC), and colorectal cancer (CRC). In this review, we summarize the recent progress on ferroptosis and its interaction with gastrointestinal diseases. Understanding the role of ferroptosis in gastrointestinal disease pathogenesis could provide novel therapeutic targets for clinical treatment