Standard and Null Weak Values

Weak value (WV) is a quantum mechanical measurement protocol, proposed by Aharonov, Albert, and Vaidman. It consists of a weak measurement, which is weighed in, conditional on the outcome of a later, strong measurement. Here we define another two-step measurement protocol, null weak value (NVW), and point out its advantages as compared to WV. We present two alternative derivations of NWVs and compare them to the corresponding derivations of WVs.Comment: 11 pages, 2 figures. To appear in Quantum Theory: A Two-Time Success Story: Yakir Aharonov Festschrif

Modern trends of scientific research and organizational methodological activities of Ural Scientific Research Institute of Dermatology, Venerology and Immunopathology

The paper presents main achivments of Ural Scientific Research Institute of Dermatology, Venerology an Immunopathology in scientific research and organizational methodological activities aimed at increasing of quality and accessibility of specialized medical care for patiens with chronical dermatoses, syphilis and other sexually transmitted diseases. Main trends of further development of Institute in current conditions of reorganization of National health care were defined.В статье представлены основные достижения Уральского научно-исследовательского института дерматовенерологии и иммунопатологии в научно-исследовательской и организационно-методической деятельности, направленной на повышение качество и доступности специализированной медицинской помощи больным хроническими дерматозами, сифилисом и другими инфекциями, передаваемыми половым путем. Определены основные направления дальнейшего развития института в современных условиях реорганизации отечественного здравоохранения

Experience in the treatment of psoriasis patients using Apremilast, a selective signalling pathway inhibitor

The article presents a brief description of Аpremilast — the target synthetic anti-inflammatory drug, which is representative of a new class of agents for the treatment of psoriasis and psoriatic arthritis. The efficiency and safety of the new drug in the treatment of patients with severe psoriasis are shown

Is conditional-pathogenic microorganisms as the reason of development of nonspecific infectious diseases of the bottom departments of sexual ways at women. Principles of classification and a diagnosis establishment

In the review variants of specific and quantitative structure are presented microflorae vagina, principal views of is conditional-pathogenic microorganisms. The attention is focused on factors of resistance of a vagina in norm and at pathology. The modern standard classifications of sexual infections, including the CART, CDC and others are analyzed, including criteria Amsel (1984) and points Nugent (1991) are described widely applied in diagnostics of infections of a vagina. Methods and ways of identification of is conditional-pathogenic microorganisms are shined. Possibilities of ordering of the diagnosis of infections of the vagina caused by is conditional-pathogenic microorganisms, according to the international qualifier of illnesses 10 revisions are resulted.В обзоре представлены варианты видового и количественного состава вагинального биотопа, основными видами условно-патогенных микроорганизмов (УПМ). Акцентировано внимание на факторах резистентности влагалища в норме и при патологии. Проанализированы современные общепринятые классификации половых инфекций, включая ВОЗ, CDC и другие, в том числе описаны широко применяемые в диагностике инфекций влагалища критерии Amsel (1984) и баллы Nugent (1991). Освещены методы и способы идентификации УПМ. Приведены возможности систематизации диагноза вагинальных инфекций, обусловленных условно-патогенными микроорганизмами, в соответствии с МКБ-10 пересмотра

Synthesis of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines and investigation of their fungistatic activity

A series of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines has been synthesized through oxidation reaction of the corresponding 3,6-disubstituted 1,2,4,5-tetrazines bearing amidine fragments. It is shown that the heterocyclic systems obtained can be modified easily at C(3) position in the reactions with aliphatic alcohols and amines. Also, the reactivity of [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines towards CH-active compounds has been studied. The obtained triazolo[1,5-b]annulated 1,2,4,5-tetrazines proved to be active in micromolar concentrations in vitro against filamentous anthropophilic and zooanthropophilic dermatophyte fungi (Trichophyton, Microsporum and Epidermofiton), which cause skin and its appendages (hair, nails) diseases. © 2022 Korotina et al.; licensee Beilstein-Institut.Ministry of Education and Science of the Russian Federation, Minobrnauka: 075-15-2020-777; Ural Branch, Russian Academy of Sciences, UB RASThis work was supported by the Ministry of Education and Science of the Russian Federation (Agreement No. 075-15-2020-777).Analytical studies were carried out using equipment of the Center for Joint Use “Spectroscopy and Analysis of Organic Compounds”, located in Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences. This work was supported by the Ministry of Education and Science of the Russian Federation (Agreement No. 075-15-2020-777)

Oxygen transport in Pr nickelates: Elucidation of atomic-scale features

Pr2NiO4+δ oxide with a layered Ruddlesden–Popper structure is a promising material for SOFC cathodes and oxygen separation membranes due to a high oxygen mobility provided by the cooperative mechanism of oxygen migration involving both interstitial oxygen species and apical oxygen of the NiO6 octahedra. Doping by Ca improves thermodynamic stability and increases electronic conductivity of Pr2 − xCaxNiO4+δ, but decreases oxygen mobility due to decreasing the oxygen excess and appearing of 1–2 additional slow diffusion channels at x ≥ 0.4, probably, due to hampering of cooperative mechanism of migration. However, atomic-scale features of these materials determining oxygen migration require further studies. In this work characteristics of oxygen diffusion in Pr2 − xCaxNiO4+δ (x = 0–0.6) are compared with results of the surface analysis by X-ray photoelectron spectroscopy and modeling of the interstitial oxygen migration by the plane-wave density functional theory calculations. According to the X-ray photoelectron spectroscopy data, the surface is enriched by Pr for undoped sample and by Ca for doped ones. The O1s peak at ~531 eV corresponding to a weakly bound form of surface oxygen located at Pr cations disappears at ~500 °C. Migration of interstitial oxygen was modeled for a I4/mmm phase of Pr2NiO4+δ. The interstitial oxygen anion repulses the apical one in the NiO6 octahedra pushing it into the tetrahedral site between Pr cations. The calculated activation barrier of this migration is equal to 0.585 eV, which reasonably agrees with the experimental value of 0.83 eV obtained by the oxygen isotope exchange method. At the same time, for the model compound Ca2NiO4+δ, obtained by isomorphic substitution of Pr by Ca in Pr2NiO4+δ, calculations implied formation of the peroxide ion comprised of interstitial and lattice oxygen species not revealed in the case of incomplete substitution (up to PrCaNiO4+δ composition). Hence, calculations in the framework of the plane-wave density functional theory provide a realistic estimation of specificity of oxygen migration features in Pr2NiO4+δ doped by alkaline-earth metals. © 2019 Elsevier B.V.Russian Science Foundation, RSF: 16-13-00112Support by Russian Science Foundation (Project 16-13-00112 ) is gratefully acknowledged

Modern methods for acne scar correction. Review

The article presents recent data on the acne scars occurrence frequency, etiopathogenesis and classification. It was conducted the effectiveness analysis of existing methods of atrophic acne scars correction, including chemical peels, dermabrasion, needling, surgical techniques, fillers augmentation, laser and light therapy, objectively were assessed side effects and complications during treatment. It were reviewed indications, advantages and disadvantages of each method. The topicality, efficacy and safety of ablative fractional thermolysis were justified.В статье представлены современные данные о частоте встречаемости, этиопатогенезе и классификации рубцов постакне. Проведен анализ эффективности существующих методик коррекции атрофических рубцов постакне, в том числе с помощью химических пилингов, дермабразии, нидлинга, хирургических техник, аугментации филлерами, лазеро- и светотерапии, дана объективная оценка побочных действий и осложнений в процессе лечения. Рассмотрены показания, преимущества и недостатки каждого метода. Обоснована актуальность, эффективность и безопасность применения аблятивного фракционного термолиза

Epidemiology, diagnosis and treatment of self-inflicted dermatoses

The article presents current information of domestic and foreign literature about the epidemiology, clinical and laboratory diagnosis and treatment of self-inflicted dermatoses.Представлены современные данные отечественной и зарубежной литературы по вопросам эпидемиологии, клинико­лабораторной диагностики и лечения самовызванных дерматозов

A case report of trichotillomania in the dermatology practice

A case study of а 9 year old child with trichotillomania, characterized by the presence of multiple foci of alopecia in temporal and occipital areas. The patient was diagnosed based on the complex assessment of clinical manifestations and consultation of psychiatrist. Trichotillomania was a symptom of neurosis-like syndrome as a result of the residual organic insufficiency. The article offers information from published sources regarding trichotillomania.Приведено описание случая трихотилломании у ребенка 9 лет, характеризовавшегося наличием многочисленных очагов облысения в височной и затылочной областях. Диагноз пациенту был установлен на основании комплексной оценки клинических проявлений и заключения психиатра. Трихотиломания была проявлением неврозоподобного синдрома, обусловленного резидуально-органической церебральной недостаточностью. Также в статье представлены современные данные литературы о трихотилломании