Stability, marginal bone loss and survival of standard and modified sand-blasted, acid-etched implants in bilateral edentulous spaces: a prospective 15-month evaluation

Objectives: Chemical modification of the already proven sand-blasted and acid-etched (SLA) implant had increased its surface wettability and consequent early-term osseointegration characteristics. The aim of this clinical trial was to compare the stability changes, success, survival, peri-implant parameters and marginal bone loss (MBL) of the early-loaded standard (SLA) and modified sand-blasted, acid-etched (modSLA) implants

Conventional Multi-Slice Computed Tomography (CT) and Cone-Beam CT (CBCT) for Computer-Aided Implant Placement. Part II: Reliability of Mucosa-Supported Stereolithographic Guides

Purpose: Deviations of implants that were placed by conventional computed tomography (CT)- or cone beam CT (CBCT)-derived mucosa-supported stereolithographic (SLA) surgical guides were analyzed in this study. Materials and Methods: Eleven patients were randomly scanned by a multi-slice CT (CT group) or a CBCT scanner (CBCT group). A total of 108 implants were planned on the software and placed using SLA guides. A new CT or CBCT scan was obtained and merged with the planning data to identify the deviations between the planned and placed implants. Results were analyzed by Mann-Whitney U test and multiple regressions (p<.05). Results: Mean angular and linear deviations in the CT group were 3.30 degrees (SD 0.36), and 0.75 (SD 0.32) and 0.80mm (SD 0.35) at the implant shoulder and tip, respectively. In the CBCT group, mean angular and linear deviations were 3.47 degrees (SD 0.37), and 0.81 (SD 0.32) and 0.87mm (SD 0.32) at the implant shoulder and tip, respectively. No statistically significant differences were detected between the CT and CBCT groups (p=.169 and p=.551, p=.113 for angular and linear deviations, respectively). Conclusions: Implant placement via CT- or CBCT-derived mucosa-supported SLA guides yielded similar deviation values. Results should be confirmed on alternative CBCT scanners

The comparison of acellular dermal matrix allografts with free gingival grafts in the augmentation of pen-implant attached mucosa: a randomised controlled trial

Purpose: The purpose of this randomised controlled trial is to compare the efficacy of two techniques for enhancing pen-implant keratinised mucosa: acellular dermal matrix allograft versus free gingival grafts

Conventional Multi-Slice Computed Tomography (CT) and Cone-Beam CT (CBCT) for Computer-Assisted Implant Placement. Part I: Relationship of Radiographic Gray Density and Implant Stability

Purpose: The relationship of conventional multi-slice computed tomography (CT)- and cone beam CT (CBCT)-based gray density values and the primary stability parameters of implants that were placed by stereolithographic surgical guides were analyzed in this study. Materials and Methods: Eighteen edentulous jaws were randomly scanned by a CT (CT group) or a CBCT scanner (CBCT group) and radiographic gray density was measured from the planned implants. A total of 108 implants were placed, and primary stability parameters were measured by insertion torque value (ITV) and resonance frequency analysis (RFA). Radiographic and subjective bone quality classification (BQC) was also classified. Results were analyzed by correlation tests and multiple regressions (p<.05). Results: CBCT-based gray density values (76597.32 voxel value) outside the implants were significantly higher than those of CT-based values (668.4 +/- 110 Hounsfield unit, p<.001). Significant relations were found among the gray density values outside the implants, ITV (adjusted r(2)=0.6142, p=.001 and adjusted r(2)=0.5166, p=.0021), and RFA (adjusted r(2)=0.5642, p=.0017 and adjusted r(2)=0.5423, p=.0031 for CT and CBCT groups, respectively). Data from radiographic and subjective BQC were also in agreement. Conclusions: Similar to the gray density values of CT, that of CBCT could also be predictive for the subjective BQC and primary implant stability. Results should be confirmed on different CBCT scanners

Morphometric analysis of small-bowel mucosa in turkish children with celiac disease and relationship with the clinical presentation and laboratory findings

WOS: 000248810300016PubMed ID: 17406838We aimed to analyze morphometric features of the small-bowel mucosa in children with celiac disease, to assess the diagnostic limit values of morphometric findings, and to examine the association of morphometric findings with the clinical presentation and laboratory findings. The study comprised 33 patients with celiac disease and 35 pediatric patients undergoing endoscopy for other causes. Biopsy specimens were reanalyzed for (1) intraepithelial lymphocytes, (2) goblet cells, (3) villous height, and (4) villous/crypt ratio. The morphometric parameters of the patients were compared with controls. Then celiac patients were divided into two groups according to the presence of total villous atrophy and clinical and laboratory findings were compared. Histologic examination revealed that goblet cells, villus height, and villous/crypt ratio were significantly lower and intraepithelial lymphocytes were significantly higher in celiac patients. Cutoff values for intraepithelial lymphocytes and goblet cells in celiac patients were 31/100 and 7.8/100 epithelial cells, respectively. Moreover, for villus height and villous/crypt ratio, cutoff values were 633 mu m and 0.72, respectively. Serum folic acid and vitamin B-12 levels were significantly lower in patients with total villous atrophy and were positively correlated with the severity of villous atrophy. We suggest that morphologic examination and laboratory data are important for definitive diagnosis. Villous/crypt ratio is the most sensitive and specific parameter, and intraepithelial lymphocytes may be used along with villous/crypt ratio, especially in the early phase. Folic acid and vitamin B-12 levels are good indicators of villous atrophy

HISTOLOGIC AND HISTOMORPHOMETRIC EVALUATION OF A HYDROPHILIC BLASTED AND ACID-ETCHED IMPLANT: AN EXPERIMENTAL STUDY IN SHEEP TIBIA

The aim of this study was to evaluate the early term osseointegration period of a modified sand-blasted and acid-etched (modSLA) implant in an experimental animal model. A total of 30 implants were placed to the tibiae of 3 sheep and insertion torque value (ITV) and resonance frequency analysis (RFA) measurements were performed. RFA measurement was repeated on 3 and 6 weeks healed implants which the animals were also sacrificed for histomorphometric analysis. Bone-to-implant contact was assessed on non-decalcified sections. Six weeks healed implants were also subjected to reverse torque test (RTT). Results were analyzed by analysis of variance (ANOVA) and Pearson correlation tests. All implants reached to strong primary stability with a mean 35.47 +/- 2.85 N/cm ITV and 71.60 +/- 2.87 RFA values for modSLA implants. After 3 weeks of healing, mean BIC% (80.64 +/- 13.89%) and RFA value (76.80 +/- 1.14) of modSLA implants were higher than of standard implants (64.39 +/- 21.2 BIC% and 74.20 +/- 4.76 RFA) and the differences were statistically significant. The differences were no more significant after 6 weeks of healing as confirmed by the RTT test (115.2 +/- 4.14 and 117.0 +/- 4.47 N/cm for standard and modSLA implants respectively, p=0.55). No correlations were found between any of the investigated parameters. Within the limits of this pilot study it can be concluded that modSLA implants achieves higher bone contact and stability at earlier time points compared to standard implants

Comparison of analgesic and anti-inflammatory efficacy of selective and non-selective cyclooxygenase-2 inhibitors in dental implant surgery

Background: The analgesic and anti-inflammatory efficacy of tenoxicam and meloxicam were evaluated in this double-masked, randomized, prospective study by analyzing pain scores and the need for rescue-analgesic agents following dental implant surgery

Evaluation of left ventricular functions by speckle-tracking echocardiography in coarctation patients

Background/Aim Two-dimensional speckle-tracking echocardiography (2D-STE) is a novel method that allows the assessment of regional myocardial function. The aim of our study was to use 2D-STE to assess left ventricular deformation in patients with coarctation of the aorta (CoA). Methods In this prospective study, patients with CoA (n = 42) and healthy controls (n = 39) were recruited. Children with CoA who visited the outpatient clinic between 2013 and 2014 were included. The data were compared with those obtained from the sex- and age-matched controls. Results The mean age of the patients was 5.8 +/- 4.5 years. Global longitudinal strain based on all three apical views and total global strain values did not appear to be different between the patient and the control groups (P = .59, P = .51, P = .15, P = .38). Hypertension was detected in 14 (33.3%) patients with CoA. There were significant differences between the global longitudinal strain values of the normotensive CoA subgroup and the hypertensive CoA subgroup (P < .05). Conclusions In our study, we found that 2D-STE total strain analysis of patients with CoA was not different from comparative healthy controls. However, we determined that 2D-STE parameters were lower in the hypertensive CoA subgroup compared to the normotensive CoA subgroup

Osseointegration and stability of a modified sand-blasted acid-etched implant: an experimental pilot study in sheep

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