Glutamic acid-insensitive [3H]kainic acid binding in goldfish brain

Kainic acid is supposed to be a specific agonist for a subclass of excitatory glutamate receptors in the vertebrate CNS. An investigation of (2 nM) [3H]kainic acid binding sites in goldfish brain, using quantitative autoradiography, has revealed evidence for two types of kainic acid receptors which differ in sensitivity to glutamic acid. -Glutamic acid (0.1-1 mM) displaced over 95% of specific [3H]kainic acid binding elsewhere in the brain but only 10-50% in the cerebellum and cerebellar crest. These structures apparently contain [3H]kainic acid binding sites that are extremely insensitive to glutamic acid. The glutamic acid-insensitive [3H]kainic acid bindings was not displaced by quisqualic acid kynurenic acid, [alpha]-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA), or , but was completely displaced by the kainic acid analogue domoic acid. The data indicate that two types of high affinity binding sites for [3H]kainic acid exist in the goldfish brain: glutamic acid-sensitive and glutamic acid-insensitive. High affinity [3H]kainic acid binding may therefore not always represent binding to subsets of glutamic acid receptors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30240/1/0000634.pd

A Global Attracting Set for the Weakly Unstable Kuramoto-Sivashinsky Equation

In this paper the existence of a global attracting set for the weakly unstable Kuramoto-Sivashinskyequation @ t U (x; t) = (\Gamma@ 4 x \Gamma 2@ 2 x \Gamma (1 \Gamma " 2 ))U (x; t) \Gamma @ x U (x; t)U (x; t) is proved for initial data which are antisymmetric with respect to the origin and have the period L. The diameter of the set is bounded in L 2 and the bound depends only on L and " : lim sup t!1 kU (:; t)k L 2 K(" 8 5 L 8 5 + "L 3 2 ) 1 Introduction In this paper we will study the long-time behavior of the weakly unstable Kuramoto-Sivashinsky equation @ t U(x; t) = \Gamma(@ 4 x + @ 2 x + 1 \Gamma " 2 )U(x; t) \Gamma @ x U(x; t)U(x; t) (1) in space dimension 1 by using the method of Collet, Eckmann, Epstein and Stubbe [CEES]. In the paper [CEES] it is shown that if the initial data belongs to L 2 per [\Gamma L 2 ; L 2 ] then the KS-equation @ t U(x; t) = \Gamma(@ 4 x + @ 2 x )U(x; t) \Gamma @ x U(x; t)U(x; t) (2) has a global attracting se..

Historische Erzehlung und critische Beurteilung der durch des Hrn. Professor Gottscheds der sechsten Auflage seiner Philosophie beygefügten Anhang Entstandenen Streitigkeit

mit Wahrheitliebender Feder entworfen von M. Christian Ziegra des Hochehrwürdigen Hamburgischen Minist. Cand.Vorlageform des Erscheinungsvermerks: Frankfurt und Leipzig, 1757

Die Geseegnete Ehren-Freude : Als unter dem ... Rectorat Des ... Constantini Ziegra ... Von dem ... Decano, Dem ... Johann Georg Neumann, dem ... Wohlgelahrten Herrn Johann Georg Diezen von Ulm ... Die Wohlverdiente Magister-Würde In Wittenberg am 16. Octobr. anno 1690 überreicht wurde; ... beglückwünschet von denen in Wittenberg Studierenden Ulmischen Lands-Leuten

Festschrift Johann Georg Dietz, Glückwunsch zur Magisterwürde 1690. - In Fraktu