24 research outputs found

    The Effects of Vitamin D on Kynurenine Level in Children With Attention Deficit Hyperactivity Disorder: An Epidemiological Study

    No full text
    Background and aims: Attention deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders with a worldwide prevalence of 5%. The prevalence is even higher among school age children ranging from 8% to 12%. ADHD is predominantly childhood-onset disorder and can persist into adolescence and adulthood to inflict long-term harm. The aim of this study was to identify the epidemiological features of ADHD and investigate the effects of vitamin D on kynurenine level in children with ADHD in Iran using ELISA method. Methods: A case-control study was designed. The study participants consisted of 40 patients with ADHD and 40 healthy participants as control group. It was conducted in Isfahan Hasht Behesht hospital from July to November 2015. All samples were treated with 1000 U of vitamin D as a tablet twice daily. The level of kynurenine was measured in blood samples using enzyme-linked immunosorbent assay (ELISA) method. Data analysis was done using SPSS software. Results: The results of this study showed that the mean vitamin D levels were 49.73 and 73.72, respectively before and after treatment in patient group, which seem significant. The mean vitamin D level after treatment was higher in patient group in comparison with control group. On the other hand, the mean kynurenine levels were 608.1 and 662.9, respectively before and after treatment in patient group. The mean kynurenine level was the same before and after treatment. Conclusion: According to the results of the study, we can conclude that vitamin D did not have a significant effect on kynurenine level in children with ADHD

    Repeatability and sensitivity of FTIR ATR spectral analysis methods for bituminous binders

    No full text
    Bituminous binders as organic materials are prone to aging mainly by oxidation. Aging changes the viscoelastic behavior of the material over time towards higher stiffness and brittleness. FTIR has been increasingly used lately to investigate impacts of oxidative aging on the chemical structure of bitumen. Especially the carbonyl and sulfoxide bands are affected by aging and commonly used to describe changes due to evolving oxidation of a binder. However, spectra obtained from FTIR can be analyzed in fundamentally different ways and the analysis method applied to a spectrum has an impact on the gathered results and especially on the repeatability and sensitivity with regards to oxidative changes. For the presented study, two bituminous binders, a PG 64-16 and an SBS modified PG 76-22 PM were aged by RTFO and PAV and subsequently measured by FTIR. The obtained spectra (up to 90 individual spectra per aging state) were analyzed employing various methods using either the original or a normalized spectrum, a band maximum or integration based calculation of indices from an absolute or tangential baseline. By analyzing the coefficient of variation of the different analysis methods, it was found that not all analysis methods exhibit the same repeatability and sensitivity. From the findings of the study it can be recommended to work with normalized spectra, use an absolute baseline and work with integration of areas for index production in favor over band maximum based methods

    Evaluation of the Relationship Between Primary Spontaneous Pneumothorax and Exercise and Return to Previous Activities in Patients Referring to Hospitals of Rasht during 2015-2017

    Get PDF
    BACKGROUND: The most common cause of primary spontaneous pneumothorax (PSP) is subpleural bleb apical rupture. Little is known about the relationship between PSP and exercise and return to exercise the time. In this study, we tend to investigate the relationship between training and PSP and time of return to exercise and previous activities.METHOD: This study was designed as a case series and the sample size included all patients diagnosed with PSP in Razi and Poursina and Aria hospitals of Rasht during 2015-2017 based on inclusion criteria. Variables were analyzed using Fisher's exact test, Chi-square, Mann Whitney U and t-test (p<0.05).RESULTS: The most common treatment type in patients was transaxillary thoracotomy with pleurodesis with iodine (TTP) in 58.2% and tube thoracostomy and pleurodesis in 41.7%, which was not statistically significant between athletes and non-athletes (p=0.806). Athletes who underwent TTP after four weeks and those treated with tube thoracostomy and pleurodesis after 8-12 weeks were advised to return to their previous activity. Of athletes, 9.5% had a recurrence; of non-athletes, 9.8% had a recurrence. Of athletes, 4.8% did not tolerate returning to their last activity; of non-athletes, 7.3% did not tolerate returning to their previous activity regardless of treatment, and this difference was not significant.CONCLUSION: Our study showed no significant difference between clinical manifestations and image findings and the frequency of treatment and complications in both athlete and non-athlete patients. There is no increase in recurrence and intolerance at the time recommended for return to previous activity
    corecore