190 research outputs found
Full velocities and propagation directions of coronal mass ejections inferred from simultaneous full-disk imaging and Sun-as-a-star spectroscopic observations
Coronal mass ejections (CMEs) are violent ejections of magnetized plasma from
the Sun, which can trigger geomagnetic storms, endanger satellite operations
and destroy electrical infrastructures on the Earth. After systematically
searching Sun-as-a-star spectra observed by the Extreme-ultraviolet Variability
Experiment (EVE) onboard the Solar Dynamics Observatory (SDO) from May 2010 to
May 2022, we identified eight CMEs associated with flares and filament
eruptions by analyzing the blue-wing asymmetry of the O III 52.58 nm line
profiles. Combined with images simultaneously taken by the 30.4 nm channel of
the Atmospheric Imaging Assembly onboard SDO, the full velocity and propagation
direction for each of the eight CMEs are derived. We find a strong correlation
between geomagnetic indices (Kp and Dst) and the angle between the CME
propagation direction and the Sun-Earth line, suggesting that Sun-as-a-star
spectroscopic observations at EUV wavelengths can potentially help to improve
the prediction accuracy of the geoeffectiveness of CMEs. Moreover, an analysis
of synthesized long-exposure Sun-as-a-star spectra implies that it is possible
to detect CMEs from other stars through blue-wing asymmetries or blueshifts of
spectral lines.Comment: Accepted by Ap
Complications after radical gastrectomy following FOLFOX7 neoadjuvant chemotherapy for gastric cancer
<p>Abstract</p> <p>Background</p> <p>This study assessed the postoperative morbidity and mortality occurring in the first 30 days after radical gastrectomy by comparing gastric cancer patients who did or did not receive the FOLFOX7 regimen of neoadjuvant chemotherapy.</p> <p>Methods</p> <p>We completed a retrospective analysis of 377 patients after their radical gastrectomies were performed in our department between 2005 and 2009. Two groups of patients were studied: the SURG group received surgical treatment immediately after diagnosis; the NACT underwent surgery after 2-6 cycles of neoadjuvant chemotherapy.</p> <p>Results</p> <p>There were 267 patients in the SURG group and 110 patients in the NACT group. The NACT group had more proximal tumours (P = 0.000), more total/proximal gastrectomies (P = 0.000) and longer operative time (P = 0.005) than the SURG group. Morbidity was 10.0% in the NACT patients and 17.2% in the SURG patients (P = 0.075). There were two cases of postoperative death, both in the SURG group (P = 1.000). No changes in complications or mortality rate were observed between the SURG and NACT groups.</p> <p>Conclusion</p> <p>The FOLFOX7 neoadjuvant chemotherapy is not associated with increased postoperative morbidity, indicating that the FOLFOX7 neoadjuvant chemotherapy is a safe choice for the treatment of local advanced gastric cancer.</p
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Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population.
To investigate the associations between dietary fatty acids and cholesterol consumption and stomach cancer (SC), we analyzed data from a population-based case-control study with a total of 1900 SC cases and 6532 controls. Dietary data and other risk or protective factors were collected by face-to-face interviews in Jiangsu Province, China, from 2003 to 2010. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multiple unconditional logistic regression models and an energy-adjusted method. The joint associations between dietary factors and known risk factors on SC were examined. We observed positive associations between dietary saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and total cholesterol and the development of SC, comparing the highest versus lowest quarters. Increased intakes of dietary SFAs (p-trend = 0.005; aOR, 1.11; 95% CI, 1.01-1.22 with a 7 g/day increase as a continuous variable) and total cholesterol (p-trend < 0.001; aOR, 1.13; 95% CI, 1.06-1.22 with a 250 mg/day increase as a continuous variable) were monotonically associated with elevated odds of developing SC. Our results indicate that dietary SFAs, MUFAs, and total cholesterol are associated with stomach cancer, which might provide a potential dietary intervention for stomach cancer prevention
Pharmacokinetic Interaction between Magnolol and Piperine in Rats
Purpose: To investigate the pharmacokinetic mechanism of interaction between magnolol and piperine when co-administered to rats.Methods: The rats were divided into five groups as follows: magnolol group (625 mg/kg); low dose of piperine group (20 mg/kg); high dose of piperine group (40 mg/kg); low dose of piperine + magnolol group; or high dose of piperine + magnolol group. Plasma samples were collected at regular time intervals after administration of a single dose of magnolol (625 mg/kg, p.o.) alone or piperine (20 or 40 mg/kg, p.o.) in the presence or absence of magnolol (625 mg/kg, p.o.). The concentrations of magnolol and piperine in plasma were measured by a validated high performance liquid chromatography (HPLC) method.Results: Compared with control, the groups given magnolol alone, concomitant administration of piperine and magnolol resulted in significant decrease (p < 0.01) in the AUC and Cmax of magnolol. Interestingly, compared with administration of piperine alone (20 mg/kg), co-administration with magnolol did not significantly (p > 0.05) alter the pharmacokinetic parameters of piperine. However, at high dose (40 mg/kg) of piperine, Cmax of piperine significantly decreased from 4.30 ± 1.47 to 2.50 ± 0.78 μg/mL (p < 0.05).Conclusion: Co-administration of magnolol and piperine decreases plasma concentration of either drug in rats, suggesting that concurrent use of magnolol with piperine or piperine-containing diets would require close monitoring for potential interactions.Keywords: Magnolol, Piperine, Pharmacokinetic interaction, Co administratio
Manipulating spatial structure of high-order quantum coherence with entangled photons
High-order quantum coherence reveals the statistical correlation of quantum
particles. Manipulation of quantum coherence of light in temporal domain
enables to produce single-photon source, which has become one of the most
important quantum resources. High-order quantum coherence in spatial domain
plays a crucial role in a variety of applications, such as quantum imaging,
holography and microscopy. However, the active control of high-order spatial
quantum coherence remains a challenging task. Here we predict theoretically and
demonstrate experimentally the first active manipulation of high-order spatial
quantum coherence by mapping the entanglement of spatially structured photons.
Our results not only enable to inject new strength into current applications,
but also provide new possibilities towards more wide applications of high-order
quantum coherence.Comment: 11 pages, 5 figure
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