471 research outputs found

    Back reaction effects on the imaginary potential of quarkonia in heavy quark cloud

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    Applying the AdS/CFT correspondence, we investigate the effect of back reaction on the imaginary part of heavy quarkonia potential in strongly coupled N=4 supersymmetric Yang-Mills (SYM) plasma. The back reaction considered here arises from the inclusion of static heavy quarks uniformly distributed over N=4 SYM plasma. It is shown that the presence of back reaction reduces the absolute value of the imaginary potential thus decreasing the thermal width. Furthermore, the results imply that back reaction enhances the quarkonia dissociation

    Imaginary potential and entropic force in non-commutative plasma

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    We study the imaginary potential and entropic force with respect to a heavy quarkonium in non-commutative N=4 super Yang-Mills (SYM) plasma at strong coupling. We compute the two quantities both along commutative as well as the non commutative coordinates of the brane. It is found that the two methods give the same result: non-commutativity reduces quarkonia dissociation

    Study of Baryon Number Transport Dynamics and Strangeness Conservation Effects Using Ω\Omega-hadron Correlations

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    In nuclear collisions at RHIC energies, an excess of Ω\Omega hyperons over Ω\overline{\Omega} is observed, indicating that Ω\Omega carries a net baryon number despite ss and sˉ\bar{s} quarks being produced in pairs. The baryon number in Ω\Omega could have been transported from the incident nuclei and/or acquired and balanced in baryon pair productions associated with other types of anti-hyperons, such as Ξ\overline{\Xi}. To investigate these two scenarios, we propose to measure correlations between Ω\Omega and KK, as well as between Ω\Omega and anti-hyperons. We will use two versions, the default and string-melting, of a multiphase transport (AMPT) model to illustrate the correlation method. We will present the Ω\Omega-hadron correlations from simulated Au+Au collisions at sNN=7.7\sqrt{s_{NN}} = 7.7 and 14.6 GeV, and discuss the dependence on collision energy and on the hadronization scheme in these two AMPT versions. These correlations from the AMPT model provide a baseline for experimental exploration of the dynamics of baryon number transport and the effects of baryon number and strangeness conservation in nuclear collisions

    Mobile defects as mediated states for charge-carrier trapping in metal halide perovskites quantum dots

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    The migration motion of defects in metal halide perovskites quantum dots (MHPQDs) results in charge-carrier trapping become more complicated. We study two-step trapping mediated by mobile defects between the ground state of MHPQDs and a fixed-depth defect using a full-configuration defect method, where all possible trapping processes mediated by these mobile defects could be reproduced and the fastest channels among them are picked out. We find that these two-step trapping processes could keep more one order of magnitude faster than these direct ones as mobile defect with the appropriate localization strength, which implies that these indirect trapping should play the crucial rule to determine the non-radiative recombination losses. These results provide the significant explanation for studying non-radiation processes of carriers in the presence of the migration defects in recent experiments. Moreover, this model will be available to analyze some key performance related defects in electronic devices.Comment: 5 pages, 3 figure

    Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas

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    <p>Abstract</p> <p>Background</p> <p><it>Pseudoalteromonas </it>is an important genus widespread in marine environment, and a lot of psychrophilic <it>Pseudoalteromonas </it>strains thrive in deep sea and polar sea. By now, there are only a few genetic systems for <it>Pseudoalteromonas </it>reported and no commercial <it>Pseudoalteromonas </it>genetic system is available, which impedes the study of <it>Pseudoalteromonas</it>, especially for psychrophilic strains. The aim of this study is to develop a heterologous expression system for psychrophilic <it>Pseudoalteromonas</it>.</p> <p>Results</p> <p>A cryptic plasmid pSM429 isolated from psychrophilic <it>Pseudoalteromonas </it>sp. BSi20429 from the Arctic sea ice, was sequenced and characterized. The plasmid pSM429 is 3874 bp in length, with a G+C content of 28%. Four putative open reading frames (ORFs) were identified on pSM429. Based on homology, the ORF4 was predicted to encode a replication initiation (Rep) protein. A shuttle vector (<it>Escherichia coli, Pseudoalteromonas</it>), pWD, was constructed by ligating pSM429 and pUC19 and inserting a chloramphenicol acetyl transferase (CAT) cassette conferring chloramphenicol resistance. To determine the minimal replicon of pSM429 and to check the functionality of identified ORFs, various pWD derivatives were constructed. All derivatives except the two smallest ones were shown to allow replication in <it>Pseudoalteromonas </it>sp. SM20429, a plasmid-cured strain of <it>Pseudoalteromonas </it>sp. BSi20429, suggesting that the <it>orf4 </it>and its flanking intergenic regions are essential for plasmid replication. Although not essential, the sequence including some repeats between <it>orf1 </it>and <it>orf2 </it>plays important roles in segregational stability of the plasmid. With the aid of pWD-derived plasmid pWD2, the erythromycin resistance gene and the <it>cd </it>gene encoding the catalytic domain of a cold-adapted cellulase were successfully expressed in <it>Pseudoalteromonas </it>sp. SM20429.</p> <p>Conclusions</p> <p>Plasmid pSM429 was isolated and characterized, and the regions essential for plasmid replication and stability were determined, helping the development of pSM429-based shuttle vectors. The shuttle vectors pWD and its derivatives could be used as cloning vectors for <it>Pseudoalteromonas</it>, offering new perspectives in the genetic manipulation of <it>Pseudoalteromonas </it>strains. With the aid of pWD-derived vector and its host, the erythromycin resistance gene and the <it>cd </it>gene of a cold-adapted protein were successfully expressed, indicating that the potential use of this system for recombinant protein production, especially for cold-adapted proteins.</p

    Pre-Late Eocene position of the Lüchun-Jinping microblock in western Yangtze Craton: constraints from Eocene-Oligocene lamprophyres in southeastern Tibet

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    The tectono-magmatic history of the Lüchun-Jinping microblock and its possible affinity with the Yangtze Craton are important elements for the reconstruction of Cenozoic plate tectonics in southeastern Tibet. In order to constrain the affinity and decipher the pre-Cenozoic paleopositon of the Lüchun-Jinping microblock, we focused on the petrogenesis of Eocene-Oligocene lamprophyres in the Lüchun-Jinping microblock. The lamprophyres yield zircon Usingle bondPb ages of 34.7–33.3 Ma and exhibit potassic-ultrapotassic features with elevated K2O/Na2O (1.4–4.0) ratios. They are characterized by high concentrations of compatible elements (e.g., Cr = 187–692 ppm, Ni = 31–218 ppm), large-ion-lithophile elements and light rare-earth elements enrichment, high-field-strength elements depletion, and high radiogenic isotopic values, i.e. (87Sr/86Sr)i = 0.7063–0.7078 and εNd(t) = −3.9 to −2.4. Combined with the low Nb/U ratios, these features suggest that the lithospheric mantle source was metasomatized by subduction-related fluids beneath the Lüchun-Jinping microblock. The relatively high Rb/Sr ratios and high heavy rare-earth element contents indicate that these lamprophyres were derived from partial melting of a phlogopite-bearing lherzolite within the spinel stability field. The parental magmas have experienced fractional crystallization of olivine and clinopyroxene during emplacement. Comprehensive comparisons between the lamprophyres from the Lüchun-Jinping microblock and the potassic-ultrapotassic mafic rocks from the western Yangtze Craton indicate that the Lüchun-Jinping microblock can be regarded as a dismembered part of the western Yangtze Craton due to continental extrusion and Cenozoic sinistral displacement. The compositional trends of the potassic-ultrapotassic mafic rocks suggest that the palaeogeographic position of the Lüchun-Jinping microblock was near the Dali area (west of the Binchuan) and close to the Jinshajiang suture zone before the Cenozoic

    Smith-Purcell radiation from time grating

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    Smith-Purcell radiation (SPR) occurs when an electron skims above a spatial grating, but the fixed momentum compensation from the static grating imposes limitations on the emission wavelength. It has been discovered that a temporally periodic system can provide energy compensation to generate light emissions in free space. Here, we introduce temporal SPR (t-SPR) emerging from a time grating and propose a generalized t-SPR dispersion equation to predict the relationship between radiation frequency, direction, electron velocity, modulation period, and harmonic orders. Compared to conventional SPR, t-SPR can: 1) Provide a versatile platform for manipulating SPR emission through temporal modulation (e.g., period, amplitude, wave shape). 2) Exhibit strong robustness to the electron-grating separation, alleviating the constraints associated with extreme electron near-field excitation. 3) Introduce additional energy channels through temporal modulation, enhancing and amplifying emission.Comment: 6 pages, 3 figure

    The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity

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    Dictamni Cortex (DC) has been reported to be associated with acute hepatitis in clinic and may lead to a selective sub-chronic hepatotoxicity in rats. Nevertheless, the potent toxic ingredient and the underlying mechanism remain unknown. Dictamnine (DTN), the main alkaloid from DC, possesses a furan ring which was suspected of being responsible for hepatotoxicity via metabolic activation primarily by CYP3A4. Herein, the present study aimed to evaluate the role of CYP3A4 in DTN-induced liver injury. The in vitro results showed that the EC50 values in primary human hepatocytes (PHH), L02, HepG2 and NIH3T3 cells were correlated with the CYP3A4 expression levels in corresponding cells. Furthermore, the toxicity was increased in CYP3A4-induced PHH by rifampicin, and CYP3A4 over-expressed (OE) HepG2 and L02 cells. Contrarily, the cytotoxicity was decreased in CYP3A4-inhibited PHH and CYP3A4 OE HepG2 and L02 cells inhibited by ketoconazole (KTZ). In addition, the hepatotoxicity of DTN in enzyme induction/inhibition mice was further investigated in the aspects of biochemistry, histopathology, and pharmacokinetics. Administration of DTN in combination with KTZ resulted in attenuated liver injury, including lower alanine transaminase and aspartate transaminase activities and greater AUC and Cmax of serum DTN, whereas, pretreatment with dexamethasone aggravated the injury. Collectively, our findings illustrated that DTN-induced hepatotoxicity correlated well with the expression of CYP3A4, namely inhibition of CYP3A4 alleviated the toxicity both in vitro and in vivo, and induction aggravated the toxicity effects
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