Applying Optimization to the Conservation Project Selection Process: A Case Study of Readiness and Environmental Protection Initiative

This study presents a thorough discussion of the efficiency and effectiveness improvement from optimization models (Binary Linear Programming and Goal Programming), as applied to the Department of Defense’s Readiness and Environmental Protection Initiative. The OM models can yield 21% and 19.1% higher benefit scores respectively, spending $13,013,473 and$31,463,473 less total acquisition costs. To achieve the same level of conservation benefits for the current rank based approach, the REPI would spend additional $20.1 million and approximate 50% of the budget. A counterpart of OM- the cost-effective analysis is observed to be inefficient when the problem becomes complex. In a real world of political environment of the conservation programs, we suggest a hybrid method of current rank based approach and the OM as well as the GP to address incompatible goals of interests groups.Environmental Economics and Policy, C6, Q24,

Concise Synthesis of a Pateamine A Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling

The marine macrolide pateamine A and its non-natural sibling DMDA-Pat A are potent translation inhibitors targeting the eukaryotic initiation factor 4A (eIF4A), an enzyme with RNA helicase activity. Although essential for every living cell, this protein target seems “drugable” since DMDA-Pat A has previously been shown to exhibit remarkable in vivo activity against two different melanoma mouse models. The novel entry into this promising compound presented herein is shorter and significantly more productive than the literature route. Key to success was the masking of the signature Z,E-configured dienoate subunit of DMDA-Pat A in the form of a 2-pyrone ring, which was best crafted by a gold-catalyzed cyclization. While the robustness of the heterocycle facilitated the entire assembly stage, the highly isomerization-prone seco-Z,E-dienoic acid could be unlocked in due time for macrolactonization by an unconventional iron-catalyzed ring opening/cross coupling. Moreover, the crystal structure analysis of an advanced intermediate gave first insights into the conformation of the macrodilactone framework of the pateamine family, which is thought to be critical for eliciting the desired biological response

Storage and retrieval of continuous-variable polarization-entangled cluster states in atomic ensembles

We present a proposal for storing and retrieving a continuous-variable quadripartite polarization-entangled cluster state, using macroscopic atomic ensembles in a magnetic field. The Larmor precession of the atomic spins leads to a symmetry between the atomic canonical operators. In this scheme, each of the four spatially separated pulses passes twice through the respective ensemble in order to map the polarization-entangled cluster state onto the long-lived atomic ensembles. The stored state can then be retrieved by another four read-out pulses, each crossing the respective ensemble twice. By calculating the variances, we analyzed the fidelities of the storage and retrieval, and our scheme is feasible under realistic experimental conditions.Comment: 6 pages, 4 figure

Distributed video coding in wireless multimedia sensor network for multimedia broadcasting

Recently the development of Distributed Video Coding (DVC) has provided the promising theory support to realize the infrastructure of Wireless Multimedia Sensor Network (WMSN), which composed of autonomous hardware for capturing and transmission of quality audio-visual content. The implementation of DVC in WMSN can better solve the problem of energy constraint of the sensor nodes due to the benefit of lower computational encoder in DVC. In this paper, a practical DVC scheme, pixel-domain Wyner-Ziv(PDWZ) video coding, with slice structure and adaptive rate selection(ARS) is proposed to solve the certain problems when applying DVC into WMSN. Firstly, the proposed slice structure in PDWZ has extended the feasibility of PDWZ to work with any interleaver size used in Slepian-wolf turbo codec for heterogeneous applications. Meanwhile, based on the slice structure, an adaptive code rate selection has been proposed aiming at reduce the system delay occurred in feedback request. The simulation results clearly showed the enhancement in R-D performance and perceptual quality. It also can be observed that system delay caused by frequent feedback is greatly reduced, which gives a promising support for WMSN with low latency and facilitates the QoS management

Nonthermal gamma-ray and X-ray flashes from shock breakout in gamma-ray bursts/supernovae

Thermal X-ray emission which is simultaneous with the prompt gamma-rays has been detected for the first time from a supernova connected with a gamma-ray burst (GRB), namely GRB060218/SN2006aj. It has been interpreted as arising from the breakout of a mildly relativistic, radiation-dominated shock from a dense stellar wind surrounding the progenitor star. There is also evidence for the presence of a mildly relativistic ejecta in GRB980425/SN1998bw, based on its X-ray and radio afterglow. Here we study the process of repeated bulk Compton scatterings of shock breakout thermal photons by the mildly relativistic ejecta. During the shock breakout process, a fraction of the thermal photons would be repeatedly scattered between the pre-shock material and the shocked material as well as the mildly relativistic ejecta and, as a result, the thermal photons get boosted to increasingly higher energies. This bulk motion Comptonization mechanism will produce nonthermal gamma-ray and X-ray flashes, which could account for the prompt gamma-ray burst emission in low-luminosity supernova-connected GRBs, such as GRB060218. A Monte Carlo code has been developed to simulate this repeated scattering process, which confirms that a significant fraction of the thermal photons get "accelerated" to form a nonthermal component, with a dominant luminosity. This interpretation for the prompt nonthermal emission of GRB060218 may imply that either the usual internal shock emission from highly relativistic jets in these low-luminosity GRBs is weak, or alternatively, that there are no highly relativistic jets in this peculiar class of bursts.Comment: Accepted for publication in ApJ; Introduction expanded, references added, conclusions unchanged; total 7 pages including 2 color figures and 1 tabl