280 research outputs found

    A Synthetic Review of Cognitive Load in Distance Interpreting: Toward an Explanatory Model

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    Distance Interpreting (DI) is a form of technology-mediated interpreting which has gained traction due to the high demand for multilingual conferences, live-streaming programs, and public service sectors. The current study synthesized the DI literature to build a framework that represents the construct and measurement of cognitive load in DI. Two major areas of research were identified, i.e., causal factors and methods of measuring cognitive load. A number of causal factors that can induce change in cognitive load in DI were identified and reviewed. These included factors derived from tasks (e.g., mode of presentation), environment (e.g., booth type), and interpreters (e.g., technology awareness). In addition, four methods for measuring cognitive load in DI were identified and surveyed: subjective methods, performance methods, analytical methods, and psycho-physiological methods. Together, the causal factors and measurement methods provide a multifarious approach to delineating and quantifying cognitive load in DI. This multidimensional framework can be applied as a tool for pedagogical design in interpreting programs at both the undergraduate and graduate levels. It can also provide implications for other fields of educational psychology and language learning and assessment

    Distortion of 3D SU8 Photonic Structures Fabricated by Four-beam Holographic Lithography with Umbrella Configuration

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    We present a quantitative study of the distortion from a three-term diamond-like structure fabricated in SU8 polymer by four-beam holographic lithography. In the study of the refraction effect, theory suggests that the lattice in SU8 should be elongated in the [111] direction but have no distortion in the (111) plane, and each triangular-like hole array in the (111) plane would rotate by ~30º away from that in air. Our experiments agree with the prediction on the periodicity in the (111) plane and the rotation due to refraction effect, however, we find that the film shrinkage during lithographic process has nearly compensated the predicted elongation in the [111] direction. In study of photonic bandgap (PBG) properties of silicon photonic crystals templated by the SU8 structure, we find that the distortion has decreased quality of PBG

    Morphine pretreatment reduces myocardial ischemiareperfusion injury in heart failure rats via GSK-3β/Cx43 signaling proteins and apoptosis-related gene, Bcl-2/Bax

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    Purpose: To investigate the effect of morphine preconditioning on myocardial ischemia reperfusion injury in heart failure rats, and the  mechanism(s) of action involvedMethods: Seventy-two healthy male Sprague-Dawley rats were assigned to 4 groups: sham, model, morphine-preconditioning and SB203580 inhibitor groups, each with 18 rats. The expressions of P-p38, p-glycogen synthetase kinase-3, and p-gap junction protein 43 in rat myocardial cells were assayed by Western blotting. The mRNA expression levels of Bcl-2 and Bax, and Bcl-2/Bax were determined using real-time fluorescence quantitative PCR.Results: The expression levels of P-p38, p-glycogen synthetase kinase-3, p-gap junction protein 43, Bcl-2 mRNA and Bcl-2/Bax were significantly higher in the pretreatment group than in the model group, while Bax mRNA was significantly lower (p < 0.05). Moreover, the mRNA expression levels of P-p38, pglycogen synthetase kinase-3, p-gap junction protein, Bcl-2, and Bcl-2/Bax in inhibitor-treated rats decreased significantly, when compared to the values for pretreatment rats; furthermore, Bax mRNA was markedly upregulated (p < 0.05).Conclusion: Morphine preconditioning significantly inhibits the expressions of GSK-3β and Cx43 signaling proteins, as well as apoptosis-related gene, Bcl-2 and Bax. In addition, it inhibits the apoptosis of rat cardiomyocytes, and reduces myocardial injury, after ischemia reperfusion, via activation of the p38 MARK signaling pathway. This provides a new strategy for clinical reduction of myocardial injury after ischemia-reperfusion. Keywords: Morphine, Pretreatment, GSK-3β/Cx43 signaling protein, Bcl-2/Bax, Heart failure, Ischemiareperfusion injur

    Effect of dexmedetomidine post-treatment on oxidative stress and apoptosis induced by myocardial ischemiareperfusion injury in rats

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    Purpose: To study the effect of dexmedetomidine on myocardial ischemia-reperfusion injury (MI/RI)- induced imbalance on oxidant-prooxidant status and apoptotic changes in rats. Methods: Ninety (90) male Wistar rats were randomly divided into three groups – sham, model and post-treatment. In model rats, the anterior descending branch of the left coronary artery was ligated for 25 min, prior to their being subjected to reperfusion for 2 h. Rats in the post-treatment group were subjected to ligation at the anterior descending branch of the left coronary artery for 25 min, but they were intravenously injected with dexmedetomidine at a dose of 10 μg/kg prior to reperfusion. There was no ligation in the sham group. Malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were assayed. Lactate dehydrogenase (LDH) and creatine kinase isoenzyme (CK-MB) levels were also evaluated. Apoptosis was measured with TdT-mediated dUTP nick end labeling (TUNEL) assay. Results: Compared with the sham group, MDA level in the model group was significantly rose, while SOD and GSH-Px activities were markedly decreased (p < 0.05). Moreover, there were higher LDH and CK-MB activities in model rats than in the sham rats, but they were significantly lower in the posttreatment group than in the model group (p < 0.05). Apoptosis was higher in model rats than in sham operation rats, but was markedly decreased in post-treatment rats than in model rats (p < 0.05). Conclusion: Post-treatment with dexmedetomidine exerts myocardial protective effect via significant reduction in oxidative stress-induced myocardial injury and apoptosis. Keywords: Dexmedetomidine, Myocardial ischemia-reperfusion injury, Antioxidant status, Programmed cell deat

    Influences of luminance contrast and ambient lighting on visual context learning and retrieval

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    Invariant spatial context can guide attention and facilitate visual search, an effect referred to as “contextual cueing.” Most previous studies on contextual cueing were conducted under conditions of photopic vision and high search item to background luminance contrast, leaving open the question whether the learning and/or retrieval of context cues depends on luminance contrast and ambient lighting. Given this, we conducted three experiments (each contains two subexperiments) to compare contextual cueing under different combinations of luminance contrast (high/low) and ambient lighting (photopic/mesopic). With high-contrast displays, we found robust contextual cueing in both photopic and mesopic environments, but the acquired contextual cueing could not be transferred when the display contrast changed from high to low in the photopic environment. By contrast, with low-contrast displays, contextual facilitation manifested only in mesopic vision, and the acquired cues remained effective following a switch to high-contrast displays. This pattern suggests that, with low display contrast, contextual cueing benefited from a more global search mode, aided by the activation of the peripheral rod system in mesopic vision, but was impeded by a more local, fovea-centered search mode in photopic vision

    Two-dimensional photonic crystals with anisotropic unit cells imprinted from poly(dimethylsiloxane) membranes under elastic deformation

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    We study structural symmetries of two-dimensional (2D) photonic crystals with anisotropic unit cells, including square- and rectangular-lattices with orientationally modulated elliptic motifs, and a compound structure consisting of circles with sixfold rotational symmetry and elliptical lines with twofold symmetry, which are created through elastic deformation of a single elastomeric membrane with circular pores. We then investigate the photonic bandgap (PBG) properties of the corresponding 2D Si posts and their tolerance to the structural deviation. We find that in the compound structure the overall PBGs are dominated by the sublattice with a higher symmetry, while the total symmetry is determined by the one with a lower symmetry

    Duration reproduction under memory pressure: Modeling the roles of visual memory load in duration encoding and reproduction

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    Duration estimates are often biased by the sampled statistical context, yielding the classical central-tendency effect, i.e., short durations are over- and long duration underestimated. Most studies of the central-tendency bias have primarily focused on the integration of the sensory measure and the prior information, without considering any cognitive limits. Here, we investigated the impact of cognitive (visual working-memory) load on duration estimation in the duration encoding and reproduction stages. In four experiments, observers had to perform a dual, attention-sharing task: reproducing a given duration (primary) and memorizing a variable set of color patches (secondary). We found an increase in memory load (i.e., set size) during the duration-encoding stage to increase the central-tendency bias, while shortening the reproduced duration in general; in contrast, increasing the load during the reproduction stage prolonged the reproduced duration, without influencing the central tendency. By integrating an attentional-sharing account into a hierarchical Bayesian model, we were able to predict both the general over- and underestimation and the central-tendency effects observed in all four experiments. The model suggests that memory pressure during the encoding stage increases the sensory noise, which elevates the central-tendency effect. In contrast, memory pressure during the reproduction stage only influences the monitoring of elapsed time, leading to a general duration over-reproduction without impacting the central tendency.Competing Interest StatementThe authors have declared no competing interest

    An incipient fault diagnosis method for rotating machinery based on bilateral spectrum and precession energy difference density spectrum

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    As an important characteristic information in incipient fault diagnosis of rotating machinery, the fault impulse signal is hard to be monitored due to the low signal amplitude and system disturbance/noise. Based on bilateral spectrum and precession energy difference density spectrum for the incipient fault diagnosis of rotating machinery, a novel diagnosis method is proposed in this paper to overcome this key problem. Compared with the existing methods to extract transient impulses from the vibrate signals, this paper designs a new fault feature parameter-precession energy difference density to characterize the feature of transient impulse. Furthermore, the complex signal and the negative frequency are introduced into the spectrum analysis and the forward and backward precession characteristics, which can be directly gained through the bilateral spectrum and relieves the problems not to be overlooked, such as high calculation, high error and time consuming. Finally, the feasibility and effectiveness of the proposed methods are demonstrated via a case study of a vertical mill reducer
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