New Intervals for the Difference Between Two Independent Binomial Proportions

In this paper we gave an Edgeworth expansion for the studentized difference of two binomial proportions. We then proposed two new intervals by correcting the skewness in the Edgeworth expansion in a direct and an indirect way. Such the bias-correct confidence intervals are easy to compute, and their coverage probabilities converge to the nominal level at a rate of O(n-½), where n is the size of the combined samples. Our simulation results suggest tat in finite samples the new interval based on the indirect method have the similar performance to the two best existing intervals in terms of coverage accuracy and average interval length and that another new interval based on the direct method had the best average coverage accuracy but could have poor coverage when two true binomial proportions are close to the boundary points

Approximation algorithms for kk-submodular maximization subject to a knapsack constraint

In this paper, we study the problem of maximizing $k$-submodular functions subject to a knapsack constraint. For monotone objective functions, we present a $\frac{1}{2}(1-e^{-2})\approx 0.432$ greedy approximation algorithm. For the non-monotone case, we are the first to consider the knapsack problem and provide a greedy-type combinatorial algorithm with approximation ratio $\frac{1}{3}(1-e^{-3})\approx 0.317$

Analysis of RIG-I-mediated innate immune response in rats with Kidney-Yang Deficiency Syndrome and its change following Yougui pill administration

Kidney-Yang Deficiency Syndrome (KYDS) is closely bound up with the immune response of immunocompromised patients. The study is to investigate whether retinoic acid-inducible gene-I (RIG-I)-mediated innate immune responseparticipates in the development of KYDS in rats and evaluate the effect of Yougui pill (YGP) on the response in KYDS rats. KYDS rats were induced by intramuscular injection of hydrocortisone at the dose of 10 mg/kg/d for 15 days. YGP at concentrations of 2.43 g/kg/d and 4.86 g/kg/d were administered intragastrically to KYDS rats for 30 days. The resultsshowed that the body weight, urinary 17-hydroxycorticosteroid (17-OHCS) level, spleen size and spleen index in KYDS rats were significantly decreased compared with healthy control rats, while YGP treatment reversed them towards normal level in a dose-dependent manner. Moreover, KYDS challenge not only strikingly increased the mRNA and protein expression levels of RIG-I, tripartite motif containing 25 (TRIM25), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) but alsomarkedly enhanced the endogenous RIG-I polyubiquitination levels. Whereas, YGP treatment effectively reversed this tendency in a dose-dependent manner. In conclusion, these findings revealed that RIG-I-mediated innate immune response was closely bound up with the development of KYDS. And YGP exhibited certain anti-inflammatory effects on KYDS rats via inhibiting the RIG-I-mediated innate immune response

Analysis of RIG-I-mediated innate immune response in rats with Kidney-Yang Deficiency Syndrome and its change following Yougui pill administration

350-359Kidney-Yang Deficiency Syndrome (KYDS) is closely bound up with the immune response of immunocompromised patients. The study is to investigate whether retinoic acid-inducible gene-I (RIG-I)-mediated innate immune response participates in the development of KYDS in rats and evaluate the effect of Yougui pill (YGP) on the response in KYDS rats. KYDS rats were induced by intramuscular injection of hydrocortisone at the dose of 10 mg/kg/d for 15 days. YGP at concentrations of 2.43 g/kg/d and 4.86 g/kg/d were administered intragastrically to KYDS rats for 30 days. The results showed that the body weight, urinary 17-hydroxycorticosteroid (17-OHCS) level, spleen size and spleen index in KYDS rats were significantly decreased compared with healthy control rats, while YGP treatment reversed them towards normal level in a dose-dependent manner. Moreover, KYDS challenge not only strikingly increased the mRNA and protein expression levels of RIG-I, tripartite motif containing 25 (TRIM25), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) but also markedly enhanced the endogenous RIG-I polyubiquitination levels. Whereas, YGP treatment effectively reversed this tendency in a dose-dependent manner. In conclusion, these findings revealed that RIG-I-mediated innate immune response was closely bound up with the development of KYDS. And YGP exhibited certain anti-inflammatory effects on KYDS rats via inhibiting the RIG-I-mediated innate immune response

N-(2-Amino-4,6-dihydroxypyrimidin-5-yl)acetamide dihydrate

The title compound, C6H8N4O3·2H2O, which crystallized as a dihydrate, has two almost planar segments viz. the pyrimidine ring and the C—N—C(=O)—C group [maxmum deviations of 0.020 (2) and 0.014 (2) Å, respectively], with a dihedral angle of 87.45°. In the crystal, the components are linked by O—H⋯O and N—H⋯O hydrogen bonds

Convolutional Hierarchical Attention Network for Query-Focused Video Summarization

Previous approaches for video summarization mainly concentrate on finding the most diverse and representative visual contents as video summary without considering the user's preference. This paper addresses the task of query-focused video summarization, which takes user's query and a long video as inputs and aims to generate a query-focused video summary. In this paper, we consider the task as a problem of computing similarity between video shots and query. To this end, we propose a method, named Convolutional Hierarchical Attention Network (CHAN), which consists of two parts: feature encoding network and query-relevance computing module. In the encoding network, we employ a convolutional network with local self-attention mechanism and query-aware global attention mechanism to learns visual information of each shot. The encoded features will be sent to query-relevance computing module to generate queryfocused video summary. Extensive experiments on the benchmark dataset demonstrate the competitive performance and show the effectiveness of our approach.Comment: Accepted by AAAI 2020 Conferenc