Examining the Effects of Feedback Type and Goal Orientation on User Participation Performance in Citizen Science Projects

How to enhance user performance becomes a key issue in citizen science research. Providing feedback is regarded as an effective design principle to promote user experience and performance in many contexts. Yet, there is a lack of study on how to design feedback to improve user experience and performance in citizen science projects. Based on feedback intervention theory and achievement goal theory, we propose a research model to depict the influenceof feedback types(task, self-referential, social feedback)on user experiences (perceived enjoyment, perceived meaning, and self-expansion), which then impact participation performance. Wealsoinvestigate whether auser\u27s dispositionalgoalorientation(mastery or performance) moderates the effects offeedback typeson user experiences. We will conduct an online experiment to validate our research model.The findings will provide the groundwork for guidelines and strategies to enhance useperformancein citizen science projects

Reducing toxicity and increasing efficiency: aconitine with liquiritin and glycyrrhetinic acid regulate calcium regulatory proteins in rat myocardial cell

Background: Compatibility of Radix Aconiti Carmichaeli and Liquorice is known to treat heart diseases such as heart failure and cardiac arrhythmias. This work answers the question that whether the active components (Aconitine, Liquiritin and Glycyrrhetinic Acid) of Radix Aconiti Carmichaeli and Liquorice could result in regulating intracellular calcium homeostasis and calcium cycling, and thereby verifies the therapeutic material basis.Materials and Methods: The myocardial cells were divided into twelve groups randomly as control group, Aconitine group, nine different dose groups that orthogonal combined with Aconitine, Liquiritin and Glycyrrhetinic Acid, and Verapamil group. The myocardial cellular survival rate and morphology were assessed. The expression of calcium regulation protein(RyR2、NCX1、DHPR-a1) in the myocardial cell by Western-blotting.Results: The results exhibited that Aconitine (120 uM) significantly damaged on myocardial cell, decreased the survival rate and expression of Na+/Ca2+ exchangers (NCX1) and dihydropteridine reducta-α1 (DHPR-a1), and increased the expression of ryanodine receptor type2 (RyR2) obviously. The compatibility groups (Aconitine, Liquiritin and Glycyrrhetinic Acid) all could against the damage on the myocardial cell by Aconitine at different levels.Conclusion: Aconitine with Liquiritin and Glycyrrhetinic Acid may regulate the expression of calcium-regulated proteins to protect myocardial cells from damage.Keywords: Aconitine, Liquiritin, Glycyrrhetinic Acid, myocardial cell, calcium regulator

The Effect of Users’ Social Capital on Idea Quality in Online Customization Communities: The Moderating Effect of Common Expertise

Existing research has focused on the online customization community of the toolkit mode. Meanwhile, research on the online customization community of the forum mode, especially regarding idea contribution behavior of users, is relatively scattered. Based on social capital theory, we construct a research model of the effect of users’ social capital on idea quality in online customization communities. Our data contains 13,457 users in the Lego Ideas Community. First, cluster analysis is used to divide users into four types: contributor, lurker, commenter, and celebrity. Then, multiple regression analysis is used to analyze the effect of users’ social capital on idea quality. The results of our study reveal the following: (1) network influence and the stickiness of users positively affect idea quality; (2) an inverted U-shaped relationship exists between the number of contributors and idea quality; (3) common expertise has a negative moderating effect on the turning point of the curve. the pain of paying theory, past research has explored this topic by comparing cash payment with card payments. With the flourishing of electronic commerce, the usage rate of mobile payment is rapidly increasing worldwide. Considering the evolution of the mainstream payment method, this study intends to compare the newly popular mobile payment with traditional payment methods (e.g., cash payment, card payment) in influencing consumers’ preferences towards hedonic products. We propose that consumers gradually establish associations between mobile payment and hedonic mindset in their daily lives. As a result, mobile payment triggers consumers’ hedonic mindsets, which contribute to their hedonic preferences. This study provides a new explanation for the effect of payment methods on consumers’ hedonic preferences from the perspective of the distinct features of mobile payment

How Feedback Focus and Regulatory Focus Influence Customers’ Co-design Behavior in Online Customization Communities

Customers’ co-design behavior in online customization communities can provide important knowledge for firms to develop customizable products and achieve business value. Feedback from firms can effectively enhance customers’ co-design behavior. Based on the relevance of information to one’s self or others, drawing upon regulatory focus theory and construal level theory, we propose a research model to depict the influence of feedback focus (self-focused vs. other-focused) on customers’ co-design behavior through their experience (perceived meaning, active discovery, and perceived empowerment) and determine whether the feedback focus congruent with the regulatory focus of contextual cues (promotion vs. prevention) can enhance customers’ experience. We will conduct an online experiment to validate our research model. The findings will extend the research on feedback information and customization

How Interaction Characteristics and Content Between Users Influence Idea Generation Performance in Open Innovation Communities

In open innovation communities (OIC), people can propose ideas according to their own needs and interact with others. OIC have emerged as a vital resource for firms to obtain users’ wisdom, which in turn stimulates product innovation and enhances competitiveness. The interaction between users in OIC is an important idea generation process. On the basis of the transactive memory system and communication accommodation theory, we propose a research model to depict the influences of interaction characteristics (i.e., specialization, credibility, coordination) between users on the idea generation performance and explore the mediation effect of content diversity. We also investigate whether firm’s feedback strategies (convergence vs. maintenance) moderate the effects of interaction characteristics and idea generation performance. We validate our model with a dataset of 9,794 ideas with 20,482 comments and 10,044 firms’ feedback in the Joint Definition Community hosted by Huawei. Results show that an inverted U-shaped relationship exists between specialization and idea generation performance; credibility and coordination have a positive effect on the idea generation performance. Furthermore, content diversity has a partial mediation effect on the relationship between interaction characteristics and idea generation performance. Convergence feedback strengthen the inverted U-shaped relationship between specialization and idea generation performance and has a significantly positive moderation effect on the impact of credibility and coordination on idea generation performance. These findings provide theoretical support and practical guidance for firms to operate OIC

Investigating the Impacts of Task characteristics in Gamified Citizen Science

Citizen science is a form of crowdsourcing service that recruits general public on scientific collaboration and co-creation. Drawing upon the job characteristic theory and self-determination theory, this paper investigated the influences of five task characteristics, including importance, interdependence, complexity, specialization, and feedback on individuals’ psychological needs, which in turn affected users’ participation intentions. We are also interested in how gamification design moderates the impacts of task characteristics on psychological needs. We conducted an online experiment to validate our research model. Our research findings showed that three psychological needs have positive impacts on participation intentions. Importance of task influences relatedness positively; feedback has a positive impact on competence; specialization and complexity affect competence negatively. Particularly, our findings confirmed the moderating effects of game elements. Research and practical implications for citizen science task design are also discussed

Improved Results on Robust Stability for Systems with Interval Time-Varying Delays and Nonlinear Perturbations

This paper investigated delay-dependent robust stability criteria for systems with interval time-varying delays and nonlinear perturbations. A delay-partitioning approach is used in this paper, the delay-interval is partitioned into multiple equidistant subintervals, a new Lyapunov-Krasovskii (L-K) functional contains some triple-integral terms, and augment terms are introduced on these intervals. Then, by using integral inequalities method together with free-weighting matrix approach, a new less conservative delay-dependent stability criterion is formulated in terms of linear matrix inequalities (LMIs), which can be easily solved by optimization algorithms. Numerical examples are given to show the effectiveness and the benefits of the proposed method

Extension of a sharp-interface immersed-boundary method for simulating parachute inflation

Abstract In this work, the sharp-interface immersed boundary (IB) method proposed by Mittal et al. (J Comput Phys 227(10):4825–4852, 2008) is extended to fluid-structure-interaction (FSI) simulation of parachute inflation by utilizing several open-source tools. The method employs a Cartesian-grid ghost-cell methodology to accurately represent the immersed boundary, and it is suitable for solving moving-boundary flows with arbitrarily complex geometries. The finite-element code CalculiX is employed to solve the structural dynamics of the parachute system. The IB flow solver is coupled with CalculiX in a minimally-invasive manner using the multi-physics coupling library preCICE. The implicit fluid-structure coupling together with the Aitken adaptive under-relaxation scheme is considered to improve the numerical accuracy and stability. The developed approach is validated by a benchmark FSI case. Numerical experiments on the inflation process of several typical parachutes are further conducted. The breathing process, flow structure, canopy displacement and drag coefficient are analyzed to demonstrate the applicability of the present approach for simulating parachute inflation

REDUCING TOXICITY AND INCREASING EFFICIENCY: ACONITINE WITH LIQUIRITIN AND GLYCYRRHETINIC ACID REGULATE CALCIUM REGULATORY PROTEINS IN RAT MYOCARDIAL CELL

Background: Compatibility of Radix Aconiti Carmichaeli and Liquorice is known to treat heart diseases such as heart failure and cardiac arrhythmias. This work answers the question that whether the active components (Aconitine, Liquiritin and Glycyrrhetinic Acid) of Radix Aconiti Carmichaeli and Liquorice could result in regulating intracellular calcium homeostasis and calcium cycling, and thereby verifies the therapeutic material basis. Materials and Methods: The myocardial cells were divided into twelve groups randomly as control group, Aconitine group, nine different dose groups that orthogonal combined with Aconitine, Liquiritin and Glycyrrhetinic Acid, and Verapamil group. The myocardial cellular survival rate and morphology were assessed. The expression of calcium regulation protein(RyR2、NCX1、DHPR-a1) in the myocardial cell by Western-blotting. Results: The results exhibited that Aconitine (120 uM) significantly damaged on myocardial cell, decreased the survival rate and expression of Na+/Ca2+ exchangers (NCX1) and dihydropteridine reducta-α1 (DHPR-a1), and increased the expression of ryanodine receptor type2 (RyR2) obviously. The compatibility groups (Aconitine, Liquiritin and Glycyrrhetinic Acid) all could against the damage on the myocardial cell by Aconitine at different levels. Conclusion: Aconitine with Liquiritin and Glycyrrhetinic Acid may regulate the expression of calcium-regulated proteins to protect myocardial cells from damage

Multiple Myeloma Patients at Various Cytogenetic Risks Benefit Differently from Autologous Stem Cell Transplantation as a Consolidation Therapy

Aim. To evaluate whether patients with multiple myeloma at various risks can still benefit the same from autologous stem cell transplantation consolidation in the era of novel agents. We retrospectively analyzed 67 consecutive myeloma patients receiving autologous stem cell transplantation after bortezomib and/or thalidomide based inductions. Totally 17 high-risk, 24 intermediaterisk, and 26 low-risk patients were enrolled, based on fluorescence in situ hybridization and ISS stage. Meanwhile, another 67 risk-, response depth-, and age-matched patients not proceeding to autologous stem cell transplantation were chosen as controls. Our preliminary data indicated that, in the high-risk subgroup, progression-free survival and overall survival were both significantly prolonged after autologous stem cell transplantation ( < 0.001 and = 0.015) while, in the intermediate-risk subgroup, neither progression-free survival nor overall survival was prolonged significantly after autologous stem cell transplantation ( > 0.05), and in the low-risk subgroup, only progression-free survival was extended significantly ( = 0.012) after autologous stem cell transplantation. Multiple variables analysis further indicated that autologous stem cell transplantation and risk stratification were two independent prognostic factors for overall survival. Our results indicated that myeloma patients at different risks all benefit from autologous stem cell transplantation consolidation even in the era of novel agents