256 research outputs found

    Relationship Determinants between AI Technology Adoption Behavior and Performance of Software Enterprises

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    With the continuous progress of science and technology, the arrival of artificial intelligence subverts the traditional industries. Enterprises urgently need to carry out technological innovation to reduce costs. The introduction of artificial intelligence technology can reduce workload and improve development efficiency for software enterprises. Reduce operating costs. This paper takes the software enterprise as the research object, takes the artificial intelligence as the independent variable and the software development cost as the dependent variable. The hypothesis is proposed through the four intermediate variables of development efficiency, management innovation, product quality, labor force and the degree of introduction of artificial intelligence. A total of 332 valid questionnaires were collected by using electronic questionnaires. The sample data are analyzed by Smartpls 3.0 software, and the data are analyzed by Algorithm, Bootstrapping, cross multiplication, structural equation and other methods. The results show that AI has a significant positive impact on software development cost, a significant positive impact on product quality, a significant positive impact on labor force, a significant positive impact on development efficiency, a significant positive impact on management innovation, and a significant positive impact on software development cost. Labor has a significant positive impact on software development costs. Development efficiency has a significant positive impact on software development cost. Management innovation has a significant positive impact on software development cost. Product quality plays an intermediary role between the introduction of artificial intelligence and the cost of software development. Development efficiency also plays an intermediary role between the introduction of artificial intelligence and the cost of software development. From the research, we know that the introduction of AI can enrich the theories of process reengineering, process optimization and management decision-making, and can also find the factors that affect output performance from the perspective of technological innovation to provide reference for future research

    Business Models In E-Sports: Starcraft 2

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    E-sports, or electronic sports, is a term referring to competitive (video)gaming, where players face off against each other in serious matches and tournaments. While e-sports have become one of the major forms of digital culture and form of business in gaming, research within e-sports is yet scarce. This exploratory study aims to further the understanding of the business ecosystem surrounding e-sports. We document and investigate different actors, players, their relationship and revenue models in one of the world’s biggest e-sports ecosystems around the game Starcraft 2. We employ the e3-value methodology, along with a qualitative analysis, to build an understanding of the e-sports ecosystem. Through this ecology analysis, five distinct revenue models are identified and the key actors of these are presented. Based on our results, e-sport players employ tournament earnings, casting, coaching, team salary and sponsorships as their main revenue models. Furthermore, the study illustrates the vital importance of sponsors to the ecosystem

    Computational Design of Wiring Layout on Tight Suits with Minimal Motion Resistance

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    An increasing number of electronics are directly embedded on the clothing to monitor human status (e.g., skeletal motion) or provide haptic feedback. A specific challenge to prototype and fabricate such a clothing is to design the wiring layout, while minimizing the intervention to human motion. We address this challenge by formulating the topological optimization problem on the clothing surface as a deformation-weighted Steiner tree problem on a 3D clothing mesh. Our method proposed an energy function for minimizing strain energy in the wiring area under different motions, regularized by its total length. We built the physical prototype to verify the effectiveness of our method and conducted user study with participants of both design experts and smart cloth users. On three types of commercial products of smart clothing, the optimized layout design reduced wire strain energy by an average of 77% among 248 actions compared to baseline design, and 18% over the expert design.Comment: This work is accepted at SIGGRAPH ASIA 2023(Conference Track

    Age-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virus

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    <p>Abstract</p> <p>Background</p> <p>The highly pandemic 2009 influenza A H1N1 virus infection showed distinguished skewed age distribution with majority of infection and death in children and young adults. Although previous exposure to related antigen has been proposed as an explanation, the mechanism of age protection is still unknown.</p> <p>Methods</p> <p>In this study, murine model of different ages were inoculated intranasally with H1N1 (A/Beijing/501/09) virus and the susceptibility and pathological response to 2009 H1N1 infection were investigated.</p> <p>Results</p> <p>Our results showed that the younger mice had higher mortality rate when infected with the same dose of virus and the lethal dose increased with age. Immunohistochemical staining of H1N1 antigens in mice lung indicated infection was in the lower respiratory tract. Most bronchial and bronchiolar epithelial cells in 4-week mice were infected while only a minor percentage of those cells in 6-month and 1-year old mice did. The young mice developed much more severe lung lesions and had higher virus load in lung than the two older groups of mice while older mice formed more inducible bronchus-associated lymphoid tissue in their lungs and more severe damage in spleen.</p> <p>Conclusions</p> <p>These results suggest that young individuals are more sensitive to H1N1 infection and have less protective immune responses than older adults. The age factor should be considered when studying the pathogenesis and transmission of influenza virus and formulating strategies on vaccination and treatment.</p

    An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus

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    Background. A 2009 global influenza pandemic caused by a novel swine-origin H1N1 influenza A virus has posted an increasing threat of a potential pandemic by the highly pathogenic avian influenza (HPAI) H5N1 virus, driving us to develop an influenza vaccine which confers cross-protection against both H5N1 and H1N1 viruses. Previously, we have shown that a tetra-branched multiple antigenic peptide (MAP) vaccine based on the extracellular domain of M2 protein (M2e) from H5N1 virus (H5N1-M2e-MAP) induced strong immune responses and cross-protection against different clades of HPAI H5N1 viruses. In this report, we investigated whether such M2e-MAP presenting the H5N1-M2e consensus sequence can afford heterosubtypic protection from lethal challenge with the pandemic 2009 H1N1 virus. Results. Our results demonstrated that H5N1-M2e-MAP plus Freund's or aluminum adjuvant induced strong cross-reactive IgG antibody responses against M2e of the pandemic H1N1 virus which contains one amino acid variation with M2e of H5N1 at position 13. These cross-reactive antibodies may maintain for 6 months and bounced back quickly to the previous high level after the 2nd boost administered 2 weeks before virus challenge. H5N1-M2e-MAP could afford heterosubtypic protection against lethal challenge with pandemic H1N1 virus, showing significant decrease of viral replications and obvious alleviation of histopathological damages in the challenged mouse lungs. 100% and 80% of the H5N1-M2e-MAP-vaccinated mice with Freund's and aluminum adjuvant, respectively, survived the lethal challenge with pandemic H1N1 virus. Conclusions. Our results suggest that H5N1-M2e-MAP has a great potential to prevent the threat from re-emergence of pandemic H1N1 influenza and possible novel influenza pandemic due to the reassortment of HPAI H5N1 virus with the 2009 swine-origin H1N1 influenza virus. © 2010 Zhao et al; licensee BioMed Central Ltd.published_or_final_versio

    An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses

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    <p>Abstract</p> <p>Background</p> <p>A growing concern has raised regarding the pandemic potential of the highly pathogenic avian influenza (HPAI) H5N1 viruses. Consequently, there is an urgent need to develop an effective and safe vaccine against the divergent H5N1 influenza viruses. In the present study, we designed a tetra-branched multiple antigenic peptide (MAP)-based vaccine, designated M2e-MAP, which contains the sequence overlapping the highly conserved extracellular domain of matrix protein 2 (M2e) of a HPAI H5N1 virus, and investigated its immune responses and cross-protection against different clades of H5N1 viruses.</p> <p>Results</p> <p>Our results showed that M2e-MAP vaccine induced strong M2e-specific IgG antibody responses following 3-dose immunization of mice with M2e-MAP in the presence of Freunds' or aluminium (alum) adjuvant. M2e-MAP vaccination limited viral replication and attenuated histopathological damage in the challenged mouse lungs. The M2e-MAP-based vaccine protected immunized mice against both clade1: VN/1194 and clade2.3.4: SZ/406H H5N1 virus challenge, being able to counteract weight lost and elevate survival rate following lethal challenge of H5N1 viruses.</p> <p>Conclusions</p> <p>These results suggest that M2e-MAP presenting M2e of H5N1 virus has a great potential to be developed into an effective subunit vaccine for the prevention of infection by a broad spectrum of HPAI H5N1 viruses.</p
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