364 research outputs found

    A New Algorithm for Bearings-Only Parametric Trajectory Tracking

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    AbstractFor the single sensor target tracking with bearings-only measurements, a novel trajectory invariable-information target tracking algorithm was proposed, and bearings-only target can be tracked by the parameter trajectory. For the measure frequency of sensor is high, the mathematic model of bearings-only tracking is analyzed by dividing the trajectory into many linearization parts. The tracking parameter of bearings-only target trajectory is deduced, so the bearings-only target can be tracked by the parameter trajectory. The simulation results show that the new algorithm has a favorable tracking precision

    Integrative metabolomic and transcriptomic analysis reveals difference in glucose and lipid metabolism in the longissimus muscle of Luchuan and Duroc pigs

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    Luchuan pig, an obese indigenous Chinese porcine breed, has a desirable meat quality and reproductive capacity. Duroc, a traditional western breed, shows a faster growth rate, high feed efficiency and high lean meat rate. Given the unique features these two porcine breeds have, it is of interest to investigate the underlying molecular mechanisms behind their distinctive nature. In this study, the metabolic and transcriptomic profiles of longissimus dorsi muscle from Duroc and Luchuan pigs were compared. A total of 609 metabolites were identified, 77 of which were significantly decreased in Luchuan compared to Duroc, and 71 of which were significantly elevated. Most differentially accumulated metabolites (DAMs) upregulated in Luchuan were glycerophospholipids, fatty acids, oxidized lipids, alcohols, and amines, while metabolites downregulated in Luchuan were mostly amino acids, organic acids and nucleic acids, bile acids and hormones. From our RNA-sequencing (RNA-seq) data we identified a total of 3638 differentially expressed genes (DEGs), 1802 upregulated and 1836 downregulated in Luchuan skeletal muscle compared to Duroc. Combined multivariate and pathway enrichment analyses of metabolome and transcriptome results revealed that many of the DEGs and DAMs are associated with critical energy metabolic pathways, especially those related to glucose and lipid metabolism. We examined the expression of important DEGs in two pathways, AMP-activated protein kinase (AMPK) signaling pathway and fructose and mannose metabolism, using Real-Time Quantitative Reverse Transcription PCR (qRT-PCR). Genes related to glucose uptake, glycolysis, glycogen synthesis, fatty acid synthesis (PFKFB1, PFKFB4, MPI, TPI1, GYS1, SLC2A4, FASN, IRS1, ULK1) are more activated in Luchuan, while genes related to fatty acid oxidation, cholesterol synthesis (CPT1A, HMGCR, FOXO3) are more suppressed. Energy utilization can be a decisive factor to the distinctive metabolic, physiological and nutritional characteristics in skeletal muscle of the two breeds we studied. Our research may facilitate future porcine breeding projects and can be used to reveal the potential molecular basis of differences in complex traits between various breeds

    The Mediating and Moderating Effects of Teacher Preference on the Relations between Students’ Social Behaviors and Peer Acceptance

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    Tested on a sample of 1,365 Hong Kong primary school students from five grades, teacher preference or the extent to which the classroom teacher likes a child in the class was found to both mediate and, to a lesser extent, moderate the relations between children’s social behaviors and peer acceptance across age groups. The mediating effect suggests that peer acceptance responds not only to the behavior of a student but also to how much the classroom teacher likes or dislikes the student. The moderating effect suggests that the associations between student social behaviors and peer acceptance differ as functions of teacher preference. The mediating teacher preference was stronger with younger children, whereas a stronger moderating teacher preference was found for the older children. These findings confirm the supposition that three social processes involving the teacher, children, and peers contribute to children’s social status and relations in the classroom

    Thermal strain induced large electrocaloric effect of relaxor thin film on LaNiO3/Pt composite electrode with the coexistence of nanoscale antiferroelectric and ferroelectric phases in a broad temperature range

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    Ferroelectric/antiferroelectric thin/thick films with large electrocaloric (EC) effect in a broad operational temperature range are very attractive in solid-state cooling devices. We demonstrated that a large positive electrocaloric (EC) effect (maximum ΔT ~ 20.7 K) in a broad temperature range (~ 110 K) was realized in Pb0.97La0.02(Zr0.65Sn0.3Ti0.05)O3 (PLZST) relaxor antiferroelectric (AFE) thin film prepared using a sol-gel method. The large positive EC effect may be ascribed to the in-plane residual thermal tensile stress during the layer-by-layer annealing process, and the high-quality film structure owing to the utilization of the LaNiO3/Pt composite bottom electrode. The broad EC temperature range may be ascribed to the great dielectric relaxor dispersion around the dielectric peak because of the coexistence of nanoscale multiple FE and AFE phases. Moreover, a large pyroelectric energy density (6.10 Jcm−3) was harvested by using an Olsen cycle, which is much larger than those (usually less than 10− Jcm−3) obtained by using direct thermal-electrical, Stirling and Carnot cycles, etc. These breakthroughs enable the PLZST thin film an attractive multifunctional material for applications in modern solid-state cooling and energy harvesting

    Zeolite-cage-lock strategy for in situ synthesis of highly nitrogen-doped porous carbon for selective separation of carbon dioxide gas

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    Porous carbon structures doped with 18.14% nitrogen and prepared by a carbonizing organic template in ZSM-39 zeolitic cages show high CO2 adsorption capacity.</p

    Inhibitory Effect of Cinobufagin on L-Type C a

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    Cinobufagin (CBG), a major bioactive ingredient of the bufanolide steroid compounds of Chan Su, has been widely used to treat coronary heart disease. At present, the effect of CBG on the L-type Ca2+ current (ICa-L) of ventricular myocytes remains undefined. The aim of the present study was to characterize the effect of CBG on intracellular Ca2+ ([Ca2+]i) handling and cell contractility in rat ventricular myocytes. CBG was investigated by determining its influence on ICa-L, Ca2+ transient, and contractility in rat ventricular myocytes using the whole-cell patch-clamp technique and video-based edge-detection and dual-excitation fluorescence photomultiplier systems. The dose of CBG (10−8 M) decreased the maximal inhibition of CBG by 47.93%. CBG reduced ICa-L in a concentration-dependent manner with an IC50 of 4 × 10−10 M, upshifted the current-voltage curve of ICa-L, and shifted the activation and inactivation curves of ICa-L leftward. Moreover, CBG diminished the amplitude of the cell shortening and Ca2+ transients with a decrease in the time to peak (Tp) and the time to 50% of the baseline (Tr). CBG inhibited L-type Ca2+ channels, and reduced [Ca2+]i and contractility in adult rat ventricular myocytes. These findings contribute to the understanding of the cardioprotective efficacy of CBG

    LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigs

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    Transcriptional profiling of Tongcheng and Landrace pigs using long serial analysis of gene expression provides insight into the molecular mechanism underlying differences in muscle growth

    Offshore subsurface characterization enabled by fiber-optic distributed acoustic sensing (DAS): An East China Sea 3D VSP survey example

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    Recent advances in distributed acoustic sensing (DAS) technology have allowed more intense measurements of subsurface and environment events, providing improved geohazard monitoring and subsurface characterization. This study discussed the subsurface evaluation enabled by the DAS-vertical seismic profiling (DAS-VSP) system in the East China Sea, China. Taking advantage of a continuous recording of the vibrational wavefields through the strain deformation of the fiber deployed along the borehole, DAS-VSP is considered an emerging and promising alternative borehole acquisition method. It provides a wider-spectrum range of recordings in a cheaper, denser, and more continuous tense compared to conventional geophones. We explored the 3D DAS-VSP signal processing and imaging strategy. Based on a set of 3D DAS-VSP data of exceptional quality, this study reviewed the common processing challenges and practical solutions for de-noise, de-ghosting, de-multiple, and wavefield separation arising from the DAS acquisition mechanism in the offshore VSP scenario. High-quality down-going multiples were separated and imaged using the pre-stack Gaussian beam depth migration in addition to the primary reflection wavefield, providing significant additional illumination to support the subsurface evaluation. The current results validated the efficiency of the DAS-VSP survey and encouraged better geological interpretation
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