Cosmological constraints from Radial Baryon Acoustic Oscillation measurements and Observational Hubble data

We use the Radial Baryon Acoustic Oscillation (RBAO) measurements, distant type Ia supernovae (SNe Ia), the observational $H(z)$ data (OHD) and the Cosmic Microwave Background (CMB) shift parameter data to constrain cosmological parameters of $\Lambda$CDM and XCDM cosmologies and further examine the role of OHD and SNe Ia data in cosmological constraints. We marginalize the likelihood function over $h$ by integrating the probability density $P\propto e^{-\chi^{2}/2}$ to obtain the best fitting results and the confidence regions in the $\Omega_{m}-\Omega_{\Lambda}$ plane.With the combination analysis for both of the {\rm $\Lambda$}CDM and XCDM models, we find that the confidence regions of 68.3%, 95.4% and 99.7% levels using OHD+RBAO+CMB data are in good agreement with that of SNe Ia+RBAO+CMB data which is consistent with the result of Lin et al's work. With more data of OHD, we can probably constrain the cosmological parameters using OHD data instead of SNe Ia data in the future.Comment: 8 pages, 6 figures, 2 tables, accepted for publication in Physics Letters

Cosmological constraints on holographic dark energy models under the energy conditions

We study the holographic and agegraphic dark energy models without interaction using the latest observational Hubble parameter data (OHD), the Union2.1 compilation of type Ia supernovae (SNIa), and the energy conditions. Scenarios of dark energy are distinguished by the cut-off of cosmic age, conformal time, and event horizon. The best-fit value of matter density for the three scenarios almost steadily located at $\Omega_{m0}=0.26$ by the joint constraint. For the agegraphic models, they can be recovered to the standard cosmological model when the constant $c$ which presents the fraction of dark energy approaches to infinity. Absence of upper limit of $c$ by the joint constraint demonstrates the recovery possibility. Using the fitted result, we also reconstruct the current equation of state of dark energy at different scenarios, respectively. Employing the model criteria $\chi^2_{\textrm{min}}/dof$, we find that conformal time model is the worst, but they can not be distinguished clearly. Comparing with the observational constraints, we find that SEC is fulfilled at redshift $0.2 \lesssim z \lesssim 0.3$ with $1\sigma$ confidence level. We also find that NEC gives a meaningful constraint for the event horizon cut-off model, especially compared with OHD only. We note that the energy condition maybe could play an important role in the interacting models because of different degeneracy between $\Omega_m$ and constant $c$.Comment: 8 pages, 4 figures, accepted for publication in PR

Characterizing water-soluble brown carbon in fine particles in four typical cities in northwestern China during wintertime: integrating optical properties with chemical processes

Brown carbon (BrC) aerosol could impact atmospheric radiative forcing and play a crucial role in atmospheric photochemistry. In this study, fine particulate matter (PM2.5) filter samples were collected synchronously in four major cities in northwestern China during the winter season (December 2019–January 2020): Lanzhou (LZ), Xining (XN), Yinchuan (YC), and Ürümqi (UR), which are represented as energy-producing and heavy manufacturing cities in China. The primary aim of the study is to explore the optical properties, sources, and chemical processes of water-soluble BrC (WS-BrC). The average mass absorption efficiency at 365 nm (MAE365) of WS-BrC at these four cities was 1.24 ± 0.19 m2 g−1 (XN), 1.19 ± 0.12 m2 g−1 (LZ), 1.07 ± 0.23 m2 g−1 (YC), and 0.78 ± 0.16 m2 g−1 (UR). The properties of WS-BrC were further investigated by an acid–base titration experiment. The results showed that the MAE365 values in all cities increased with higher pH values (2–11), while the fluorescence intensities of water extracts fluctuated with pH values, being stronger under both highly acidic and basic conditions. The sensitivity to pH variation was most pronounced in the WS-BrC samples from YC and LZ, indicating the important contribution of acid or base functional group compounds in these locations. Additionally, the study revealed significant photo-enhancement (LZ) or photo-bleaching (YC and UR) phenomena of WS-BrC in different cities. These results suggest that the sources and/or chemical processes of WS-BrC varied among the cities. The sources and chemical processes of WS-BrC were further explored by a combination of parallel factor analysis (PARAFAC) on excitation–emission matrix (EEM) spectra of WS-BrC and positive matrix factorization analysis (PMF) on high-resolution mass spectra of water-soluble organic aerosol (WSOA). Six PARAFAC components were identified, including three humic-like substances (HULIS; two less oxygenated (LO) HULIS and one highly oxygenated (HO) HULIS), two protein-like or phenol-like substances (PLS), and one undefined substance. Four PMF factors were identified, including a water-soluble primary OA (WS-POA), a less oxidized oxygenated OA associated with coal combustion-induced WSOA (LO-OOA), and two highly oxidized oxygenated OAs resulting from photochemical oxidation and aqueous-phase oxidation transformations (HO-OOA1 and HO-OOA2). WS-POA was determined to be the most significant source of light absorption, accounting for 30 %–60 % based on multiple linear regression models, and it showed a significant correlation with PLS and LO-HULIS components. The loss of light absorption of WS-POA was found to occur through its conversion to LO-OOA and HO-OOAs through photochemical or aqueous reactions, with HO-OOAs being significantly correlated with the HO-HULIS component. These processes can be clearly illustrated by integrating optical properties and chemical composition using a Van Krevelen diagram and an EEM plot.</p

Probing the Time Variation of a Fine Structure Constant Using Galaxy Clusters and the Quintessence Model

We explore a possible time variation of the fine structure constant (α ≡ e2/ℏ c) using the Sunyaev-Zel'dovich effect measurements of galaxy clusters along with their X-ray observations. Specifically, the ratio of the integrated Comptonization parameter YSZ DA2 and its X-ray counterpart YX is used as an observable to constrain the bounds on the variation of α. Considering the violation of the cosmic distance duality relation, this ratio depends on the fine structure constant of ∼ α3. We use the quintessence model to provide the origin of α time variation. In order to give a robust test on α variation, two galaxy cluster samples, the 61 clusters provided by the Planck collaboration and the 58 clusters detected by the South Pole Telescope (SPT), are collected for analysis. Their X-ray observations are given by the XMM-Newton survey. Our results give ζ =-0.203-0.099+0.101 for the Planck sample and ζ =-0.043-0.148+0.165 for the SPT sample, indicating that α is constant with redshift within 3σ and 1σ for the two samples, respectively. © 2021. The American Astronomical Society. All rights reserved

Estimations of the cosmological parameters from the observational variation of the fine structure constant

We present the constraints on the Quintessence scalar field model from the observational data of the variation of the fine structure constant obtained from Keck and VLT telescopes. Within the theoretical frame proposed by Bekenstein, the constraints on the parameters of the Quintessence scalar field model are obtained. By the consideration of the prior of $\Omega_{m0}$ as WMAP 7 suggests, we obtain various results of the different samples. Based on these results, we also calculate the probability density function of the coupling constant $\zeta$. The best-fit values show a consistent relationship between $\zeta$ and the different experimental results. In our work, we test two different potential models, namely, the inverse power law potential and the exponential potential. The results show that both the large value of the parameters in the potential and the strong coupling can cause the variation of fine structure constant.Comment: 17 pages, 10 figures, 1 table. Joint constraints added, a few comments added. Accepted for publication in RAA. Updated to match the accepted versio

Acupuncture Attenuates Anxiety-Like Behavior by Normalizing Amygdaloid Catecholamines during Ethanol Withdrawal in Rats

Previously, we demonstrated acupuncture at acupoint HT7 (Shen-Men) attenuated ethanol withdrawal syndrome by normalizing the dopamine release in nucleus accumbens shell. In the present study, we investigated the effect of acupuncture on anxiety-like behavior in rats and its relevant mechanism by studying neuro-endocrine parameters during ethanol withdrawal. Rats were treated with 3 g kg−1day−1 of ethanol (20%, w/v) or saline by intraperitoneal injections for 28 days. The rats undergoing ethanol withdrawal exhibited anxiety-like behavior 72 h after the last dose of ethanol characterized by the decrease of time spent in the open arms of the elevated plus maze compared with the saline-treated rats (P < .05). Radioimmunoassay exhibited there were notably increased concentrations of plasma corticosterone in ethanol-withdrawn rats compared with saline-treated rats (P < .05). Additionally, high performance liquid chromatography analysis also showed the levels of norepinephrine and 3-methoxy-4-hydroxy-phenylglycol were markedly increased while the levels of dopamine and 3,4-dihydroxyphenylacetic acid were significantly decreased in the central nucleus of the amygdala of ethanol-withdrawn rats compared with saline-treated rats (P < .01). Acupuncture groups were treated with acupuncture at acupoint HT7 or PC6 (Nei-Guan). Acupuncture at HT7 but not PC6 greatly attenuated the anxiety-like behavior during ethanol withdrawal as evidenced by significant increases in the percentage of time spent in open arms (P < .05). In the meantime, acupuncture at HT7 also markedly inhibited the alterations of neuro-endocrine parameters induced by ethanol withdrawal (P < .05). These results suggest that acupuncture may attenuate anxiety-like behavior during ethanol withdrawal through regulation of neuro-endocrine system

In vitro Studies and Clinical Observations Imply a Synergistic Effect Between Epstein-Barr Virus and Dengue Virus Infection

Dengue virus (DENV) infection can lead to a complex spectrum of clinical outcomes, ranging from asymptomatic infection to life-threatening severe dengue. The reasons for thus drastically varying manifestations of the disease remain an enigma. Herein, we reported an original discovery of the synergistic effect between preexisting Epstein–Barr virus (EBV) infection and DENV superinfection in vitro and of a strong correlation of these two viruses in the clinical samples from dengue patients. We showed that (I) DENV-2 infection of an EBV-positive cell line (EBV + Akata cell) reactivated EBV, and it could be blocked by wortmannin treatment. (II) Examination of human peripheral blood mononuclear cell (PBMC) samples from dengue patients revealed significantly elevated cell-associated EBV DNA copy number at the time of hospitalization vs. at the time of disease recovery in most individuals. (III) EBV infection promoted DENV propagation in both EBV-hosting B cells and indirectly in THP-1 cells, supported by the following evidence: (A) EBV + Akata cells were more permissive to DENV-2 infection compared with Akata cells harboring no EBV virus (EBV- Akata cells). (B) Low-molecular weight fraction secreted from EBV + Akata cells could enhance DENV-2 propagation in monocytic THP-1 cells. (C) While reactivation of EBV in EBV + Akata cells further increased DENV-2 yield from this cell line, pharmacological inhibition of EBV replication by acyclovir had the opposite effect. To our knowledge, this is the first investigation demonstrating a positive correlation between EBV and DENV in vitro and in human biospecimens

Validation of the Oxford classification of IgA nephropathy for pediatric patients from China

BACKGROUND: The Oxford classification of IgA nephropathy (IgAN) provides a useful tool for prediction of renal prognosis. However, the application of this classification in children with IgAN needs validation in different patient populations. METHODS: A total of 218 children with IgAN from 7 renal centers in China were enrolled. The inclusion criteria was similar to the original Oxford study. RESULTS: There were 98 patients (45%) with mesangial proliferation (M1), 51 patients (23%) with endocapillary proliferation (E1), 136 patients (62%) with segmental sclerosis/adhesion lesion (S1), 13 patients (6%) with moderate tubulointerstitial fibrosis (T1 26-50% of cortex scarred), and only 2 patients (1%) with severe tubulointerstitial fibrosis (T2, >50% of cortex scarred). During a median follow-up duration of 56 months, 24 children (12.4%) developed ESRD or 50% decline in renal function. In univariate COX analysis, we found that tubular atrophy/interstitial fibrosis (HR 4.3, 95%CI 1.8-10.5, P < 0.001) and segmental glomerulosclerosis (HR 9.2 1.2-68.6, P = 0.03) were significant predictors of renal outcome. However, mesangial hypercellularity, endocapillary proliferation, crescents, and necrosis were not associated with renal prognosis. In the multivariate COX regression model, none of these pathologic lesions were shown to be independent risk factors of unfavorable renal outcome except for tubular atrophy/interstitial fibrosis (HR 2.9, 95%CI 1.0-7.9 P = 0.04). CONCLUSIONS: We confirmed tubular atrophy/interstitial fibrosis was the only feature independently associated with renal outcomes in Chinese children with IgAN

The accelerated scaling attractor solution of the interacting agegraphic dark energy in Brans-Dicke theory

We investigate the interacting agegraphic dark energy in Brans-Dicke theory and introduce a new series general forms of dark sector coupling. As examples, we select three cases involving a linear interaction form (Model I) and two nonlinear interaction form (Model II and Model III). Our conclusions show that the accelerated scaling attractor solutions do exist in these models. We also find that these interacting agegraphic dark energy modes are consistent with the observational data. The difference in these models is that nonlinear interaction forms give more approached evolution to the standard $\Lambda$CDM model than the linear one. Our work implies that the nonlinear interaction forms should be payed more attention.Comment: 9 pages, 10 figures, accepted in Eur. Phys. J.