2,623 research outputs found
Rainbow tensor model with two tensors of rank three
We give the keystone operators and construct a graded ring with tree and loop
operators. In terms of the keystones operators, connected tree and loop
operators in the ring, we construct the rainbow tensor model with two tensors
of rank-3 and present its -representation. Moreover we derive the compact
expressions of correlators from the -representation and analyze the free
energy in large limit. In addition, we establish the correspondence between
two colored Dyck walks in the Fredkin spin chain and tree operators in the
ring. Based on the classification Dyck walks, we give the number of tree
operators with the given level. Furthermore, for the entanglement entropy of
the Fredkin spin chain, we show the entanglement scaling beyond logarithmic
scaling in the ordinary critical systems from the viewpoint of tensor model.Comment: 27 pages, 15 figures, 1 tabl
Determinant representations for scalar products of the XXZ Gaudin model with general boundary terms
We obtain the determinant representations of the scalar products for the XXZ
Gaudin model with generic non-diagonal boundary terms.Comment: Latex file, 17 page
A Hybrid Model Based on Support Vector Machine for Bus Travel-Time Prediction
Effective bus travel time prediction is essential in transit operation system. An improved support vector machine (SVM) is applied in this paper to predict bus travel time and then the efficiency of the improved SVM is checked. The improved SVM is the combination of traditional SVM, Grubbs’ test method and an adaptive algorithm for bus travel-time prediction. Since error data exists in the collected data, Grubbs’ test method is used for removing outliers from input data before applying the traditional SVM model. Besides, to decrease the influence of the historical data in different stages on the forecast result of the traditional SVM, an adaptive algorithm is adopted to dynamically decrease the forecast error. Finally, the proposed approach is tested with the data of No. 232 bus route in Shenyang. The results show that the improved SVM has good prediction accuracy and practicality
Prognostic nomogram for bladder cancer with brain metastases: a National Cancer Database analysis.
BACKGROUND: This study aimed to establish and validate a nomogram for predicting brain metastasis in patients with bladder cancer (BCa) and assess various treatment modalities using a primary cohort comprising 234 patients with clinicopathologically-confirmed BCa from 2004 to 2015 in the National Cancer Database.
METHODS: Machine learning method and Cox model were used for nomogram construction. For BCa patients with brain metastasis, surgery of the primary site, chemotherapy, radiation therapy, palliative care, brain confinement of metastatic sites, and the Charlson/Deyo Score were predictive features identified for building the nomogram.
RESULTS: For the original 169 patients considered in the model, the areas under the receiver operating characteristic curve (AUC) were 0.823 (95% CI 0.758-0.889, P \u3c 0.001) and 0.854 (95% CI 0.785-0.924, P \u3c 0.001) for 0.5- and 1-year overall survival respectively. In the validation cohort, the nomogram displayed similar AUCs of 0.838 (95% CI 0.738-0.937, P \u3c 0.001) and 0.809 (95% CI 0.680-0.939, P \u3c 0.001), respectively. The high and low risk groups had median survivals of 1.91 and 5.09 months for the training cohort and 1.68 and 8.05 months for the validation set, respectively (both P \u3c 0.0001).
CONCLUSIONS: Our prognostic nomogram provides a useful tool for overall survival prediction as well as assessing the risk and optimal treatment for BCa patients with brain metastasis
Deep learning assisted jet tomography for the study of Mach cones in QGP
Mach cones are expected to form in the expanding quark-gluon plasma (QGP)
when energetic quarks and gluons (called jets) traverse the hot medium at a
velocity faster than the speed of sound in high-energy heavy-ion collisions.
The shape of the Mach cone and the associated diffusion wake are sensitive to
the initial jet production location and the jet propagation direction relative
to the radial flow because of the distortion by the collective expansion of the
QGP and large density gradient. The shape of jet-induced Mach cones and their
distortions in heavy-ion collisions provide a unique and direct probe of the
dynamical evolution and the equation of state of QGP. However, it is difficult
to identify the Mach cone and the diffusion wake in current experimental
measurements of final hadron distributions because they are averaged over all
possible initial jet production locations and propagation directions. To
overcome this difficulty, we develop a deep learning assisted jet tomography
which uses the full information of the final hadrons from jets to localize the
initial jet production positions. This method can help to constrain the initial
regions of jet production in heavy-ion collisions and enable a differential
study of Mach-cones with different jet path length and orientation relative to
the radial flow of the QGP in heavy-ion collisions
Mild temperature photothermal assisted anti-bacterial and anti-inflammatory nanosystem for synergistic treatment of post-cataract surgery endophthalmitis
Rationale: Endophthalmitis, which is one of the severest complications of cataract surgeries, can seriously threaten vision and even lead to irreversible blindness owing to its complicated microenvironment, including both local bacterial infection and severe inflammation. It is urgent to develop a comprehensive treatment for both anti-bacterial and anti-inflammatory effects. Methods: Herein, we developed AuAgCu2O-bromfenac sodium nanoparticles (AuAgCu2O-BS NPs), which was designed to combine anti-bacterial and anti-inflammatory effects for integrated therapy of endophthalmitis after cataract surgery. The AuAgCu2O-BS NPs could eradicate methicillin-resistant Staphylococcus aureus (MRSA) bacterial strain relied on their photodynamic effects and the release of metal ions (Ag+ and Cu+) by the hollow AuAgCu2O nanostructures mediated mild photothermal effects. The anti-inflammatory drug, bromfenac sodium, released from the nanoparticles were able to significantly reduce the local inflammation of the endophthalmitis and promote tissue rehabilitation. In vivo bacterial elimination and anti-inflammation were confirmed by a postcataract endophthalmitis rabbit model. Results: Excellent antibacterial ability of AuAgCu2O-BS NPs was verified both in vitro and in vivo. Ophthalmological clinical observation and pathologic histology analysis showed prominent treatment of inflammatory reaction. Importantly, the mild temperature photothermal effect not only promoted the release of metal ions and bromfenac sodium but also avoided the thermal damage of the surrounding tissues, which was more suitable for the practical application of ophthalmology due to the complex structure of the eyeball. Moreover, superior biocompatibility was approved by the preliminary toxicity investigations, including low cytotoxicity, negligible damage to major organs, and stable intraocular pressure. Conclusions: Our studies of nanosystem provide a promising synergic therapeutic strategy for postcataract endophthalmitis treatment with favorable prognosis and promise in clinical translations.Peer reviewe
Scalar products of the open XYZ chain with non-diagonal boundary terms
With the help of the F-basis provided by the Drinfeld twist or factorizing
F-matrix of the eight-vertex solid-on-solid (SOS) model, we obtain the
determinant representations of the scalar products of Bethe states for the open
XYZ chain with non-diagonal boundary terms. By taking the on shell limit, we
obtain the determinant representations (or Gaudin formula) of the norms of the
Bethe states.Comment: Latex file, 28 page
Identification of new antibacterial targets in RNA polymerase of Mycobacterium tuberculosis by detecting positive selection sites
Bacterial RNA polymerase (RNAP) is an effective target for antibacterial treatment. In order to search new potential targets in RNAP of Mycobacterium, we detected adaptive selections of RNAP related genes in 13 strains of Mycobacterium by phylogenetic analysis. We first collected sequences of 17 genes including rpoA, rpoB, rpoC, rpoZ, and sigma factor A-M. Then maximum likelihood trees were constructed, followed by positive selection detection. We found that sigG shows positive selection along the clade (M. tuberculosis, M. bovis), suggesting its important evolutionary role and its potential to be a new antibacterial target. Moreover, the regions near 933Cys and 935His on the rpoB subunit of M. tuberculosis showed significant positive selection, which could also be a new attractive target for anti-tuberculosis drugs
Free field realization of the exceptional current superalgebra \hat{D(2,1;\a)}_k
The free-field representations of the D(2,1;\a) current superalgebra and
the corresponding energy-momentum tensor are constructed. The related screening
currents of the first kind are also presented.Comment: Latex file, 10 page
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