Nonadiabatic simulation study of photoisomerization of azobenzene: Detailed mechanism and load-resisting capacity

Nonadiabatic dynamical simulations were carried out to study cis-to-trans isomerization of azobenzene under laser irradiation and/or external mechanical loads. We used a semiclassical electron-radiation-ion dynamics method that is able to describe the coevolution of the structural dynamics and the underlying electronic dynamics in a real-time manner. It is found that azobenzene photoisomerization occurs predominantly by an out-of-plane rotation mechanism even under a nontrivial resisting force of several tens of piconewtons. We have repeated the simulations systematically for a broad range of parameters for laser pulses, but could not find any photoisomerization event by a previously suggested in-plane inversion mechanism. The simulations found that the photoisomerization process can be held back by an external resisting force of 90 - 200 pN depending on the frequency and intensity of the lasers. This study also found that a pure mechanical isomerization is possible from the cis state if the azobenzene molecule is stretched by an external force of 1250 -1650 pN. Remarkably, the mechanical isomerization first proceeds through a mechanically activated inversion, and then is diverted to an ultrafast downhill rotation that accomplishes the isomerization. Implications of these findings to azobenzene-based nanomechanical devices are discussed.Comment: 9 printed page

An Access Control Framework for Multilayer Rail Transit Systems Based on Trust and Sensitivity Attributes

The construction of multilayer rail transit systems is a necessary way to realize “modern metropolitan areas on rail”, improve resource sharing, and increase travel services, where data integration is of utmost importance. To break data silos and realize data flow between different rail systems, a fine-grained access control framework is proposed in this paper. Through categorical and hierarchical schemes, a universal security scale is established for cross-domain data resources. Based on this, a trust and sensitivity attribute-based access control (TSABAC) model is put forward to describe the characteristics of the access control process. Furthermore, the method of policy integration is discussed, as well as the solution to the policy incompatibility problem, due to cross-domain interaction. As shown in practical application and simulation analysis, this framework can meet the requirements of security and granularity. This research is of great significance for promoting the high-quality development of urban agglomerations and metropolitan areas, and improving the quality and efficiency of rail transit

Name Your Style: Text-Guided Artistic Style Transfer

International audienceImage style transfer has attracted widespread attentionin the past years. Despite its remarkable results, it requiresadditional style images available as references, making itless flexible and inconvenient. Using text is the most natural way to describe the style. Text can describe implicit abstract styles, like styles of specific artists or art movements. In this work, we propose a text-driven style transfer (TxST) that leverages advanced image-text encoders to control arbitrary style transfer. We introduce a contrastive training strategy to effectively extract style descriptions from the image-text model (i.e., CLIP), which aligns stylization with the text description. To this end, we also propose a novel cross-attention module to fuse style and content features. Finally, we achieve an arbitrary artist-aware style transfer to learn and transfer specific artistic characters such as Picasso, oil painting, or a rough sketch. Extensive experiments demonstrate that our approach outperforms the stateof-the-art methods. Moreover, it can mimic the styles of one or many artists to achieve attractive results, thus highlighting a promising future direction

Gasification Characteristics of High Moisture Content Lignite under CO2 and Auto-Generated Steam Atmosphere in a Moving Bed Tubular Reactor

An external thermal high-temperature continuous feed moving bed tubular reactor was used for the gasification of high moisture content lignite (30.41 wt.%) under CO2 and an auto-generated steam atmosphere. The objectives of this study are to illustrate the synergistic gasification characteristics of high moisture content lignite and CO2 in the tubular reactor; CO2 and auto-generated steam (steam released from the lignite) were used as gasification agents for lignite gasification. The effects of temperature and CO2 flow rate were also investigated. Experimental results showed that when the gasification temperature increased from 800 °C to 1000 °C, the H2 yield also increased from 8.45 mol kg−1 to 17.86 mol kg−1. This may indicate that the H2O-CO2 gasification of semi-coke was enhanced with the rise in temperature. At 900 °C, the gas yield increased with the increase in CO2 flow rate, while the yield of char and liquid product showed an opposite trend. The lower heating value of the H2-rich syngas varied from 11.73 MJ m−3 to 12.77 MJ Nm−3. The experimental results proved that the high moisture content lignite in-situ CO2 gasification process is an effective methodology for the clean and efficient utilization of lignite

Gasification Characteristics of High Moisture Content Lignite under CO₂ and Auto-Generated Steam Atmosphere in a Moving Bed Tubular Reactor

An external thermal high-temperature continuous feed moving bed tubular reactor was used for the gasification of high moisture content lignite (30.41 wt.%) under CO2 and an auto-generated steam atmosphere. The objectives of this study are to illustrate the synergistic gasification characteristics of high moisture content lignite and CO2 in the tubular reactor; CO2 and auto-generated steam (steam released from the lignite) were used as gasification agents for lignite gasification. The effects of temperature and CO2 flow rate were also investigated. Experimental results showed that when the gasification temperature increased from 800 °C to 1000 °C, the H2 yield also increased from 8.45 mol kg−1 to 17.86 mol kg−1. This may indicate that the H2O-CO2 gasification of semi-coke was enhanced with the rise in temperature. At 900 °C, the gas yield increased with the increase in CO2 flow rate, while the yield of char and liquid product showed an opposite trend. The lower heating value of the H2-rich syngas varied from 11.73 MJ m−3 to 12.77 MJ Nm−3. The experimental results proved that the high moisture content lignite in-situ CO2 gasification process is an effective methodology for the clean and efficient utilization of lignite

Effect of eradication of Helicobacter pylori on expression levels of FHIT, IL-8 and P73 in gastric mucosa of first-degree relatives of gastric cancer patients.

OBJECTIVES:Helicobacter pylori (H. pylori) infection plays an important role in the carcinogenesis and development of gastric cancer. Eradication of H. pylori can effectively reduce the risk of gastric cancer, but the underlying mechanisms are not fully understood. This study aimed to investigate the effect of eradication of H. pylori on the expression levels of FHIT, IL-8 and P73 in the gastric mucosa of first-degree relatives of gastric cancer patients. METHODS:One hundred and thirty-two patients with functional dyspepsia having first-degree relatives with gastric cancer were prospectively recruited in this study. Nine patients presented with H. pylori infection and family histories of gastric cancer, 61 with H. pylori infection and without family histories of gastric cancer, 6 without H. pylori infection and with family histories of gastric cancer, and 56 without H. pylori infection and family histories of gastric cancer. The protein and mRNA expression levels of FHIT, IL-8 and P73 in gastric mucosa of the subjects were detected by immunohistochemical staining and polymerase chain reaction, respectively. RESULTS:Compared with the patients without H. pylori infection and family histories of gastric cancer, both the protein and mRNA levels of FIHT significantly decreased in patients with H. pylori infection and/or family histories of gastric cancer, and both the protein and mRNA levels of IL-8 significantly increased. After eradication of H. pylori, both the protein and mRNA levels of FHIT were significantly higher, and both the protein and mRNA levels of IL-8 were significantly lower. However, H. pylori infection and family histories of gastric cancer had no major effect on P73 expression. CONCLUSIONS:Down-regulation of FHIT and up-regulation of IL-8 may be involved in the pathogenesis of H. pylori infection in the first-degree relatives of gastric cancer patients

Volatiles from Eucalyptus Trunks and Forest Floor Humus Influence the Habitat Transfer, Host Selection, and Aggregation of <i>Endoclita signifer</i> Larvae

Endoclita signifer is a major wood-boring pest of eucalyptus trees in China, and its third instar larvae can accurately find and infest eucalyptus trees in mixed-species forests, although it can also feed on another 51 tree species in the same planted area. A total of 34 volatile compounds were identified from eucalyptus trunks, including non-infested and infested trunks with single or multiple (more than three) larval entrance cover packets, and forest floor humus. Of these, o-cymene showed a strong gas chromatography-electroantennographic detection (GC-EAD) activity and significant attraction of the third instar E. signifer larvae. Higher abundance of alpha-phellandrene, o-cymene, and the unique 2-phenyl-2-propanol in the volatile profile from infested eucalyptus trunks indicated that they were herbivore-induced plant volatiles (HIPVs). The larvae showed significantly higher attraction to volatile blends, especially those from infested eucalyptus trunks, than to single volatiles. A blend of the three HIPVs, α-pinene, D-limonene, and n-butyl ether may serve as an attractant for the control of E. signifer larvae in eucalyptus plantations. Further, exposure of third instar E. signifer larvae to some of these volatiles which also elicited electroantennogram and behavioral responses, influenced expressions of some olfactory proteins. Our results show that third instar E. signifer larvae can recognize o-cymene from host eucalyptus trunks and are attracted to the trunk by the three HIPVs when they shift their habitats from the forest floor humus to the tree trunks

Biointerface by cell growth on layered graphene–artificial peroxidase–protein nanostructure for in situ quantitative molecular detection

A smart multifunctional biointerface with dimensional compatibility and good electrical conductivity is constructed by growing human breast adenocarcinoma cells on layered graphene–artificial peroxidase–extracellular matrix protein and further used to in situ selectively and quantatively detect reactive oxygen species, for the first time discovering that the number of extracellular released hydrogen peroxide molecules is around 1011 per cell

Data from: Heterogeneous distributional responses to climate warming: evidence from rodents along a subtropical elevational gradient

Background: Understanding whether species' elevational range is shifting in response to directional changes in climate and whether there is a predictable pattern in that response is one of the major challenges in ecology. However, so far very little is known about the distributional responses of subtropical species to climate change, especially for small mammals. In this study, we examined the elevational range shifts at three range points (upper and lower range limits and abundance-weighted range centre) of rodents over a 30-year period (1986 to 2014-2015), in a subtropical forest of Southwest China. We also examined the influences of four ecological traits (body mass, habitat breadth, diet and daily activity pattern) on the upslope shifts in species' abundance-weighted range centres. Results: Despite the warming trend between 1986 and 2015, the eleven rodent species in analysis displayed heterogeneous dynamics at each of the three range points. Species which have larger body sizes and narrower habitat breadths, show both diurnal and nocturnal activities and more specialized dietary requirements, are more likely to exhibit upslope shifts in abundance-weighted range centres. Conclusions: Species' distributional responses can be heterogeneous even though there are directional changes in climate. Our study indicates that climate-induced alleviation of competition and lag in response may potentially drive species' range shift, which may not conform to the expectation from climate change. Difference in traits can lead to different range dynamics. Our study also illustrates the merit of multi-faceted assessment in studying elevational range shifts