Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity

© 2016, Springer Science+Business Media New York.The aggregation and adsorption properties of a new complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide were studied by methods of conductometry, tensiometry, and dynamic light scattering. The critical micelle concentration, size of the aggregates, and adsorption characteristics at the water—air interface were determined. The antimicrobial and antifungal effects were established. The studied properties of the complex were compared with the properties of the ligand and cationic surfactants with a head group of the cyclic and acyclic types. The enhanced aggregation ability of the complex and its improved biological activity were shown

РАК МОЛОЧНОЙ ЖЕЛЕЗЫ И БЕРЕМЕННОСТЬ: ОСОБЕННОСТИ ДИАГНОСТИКИ И ЛЕЧЕНИЯ

Breast cancer researches in recent years have shown that it is the most common form of cancer in women during pregnancy. According to the data from international statistical institutes, this form of cancer in women younger than 45 years account for 8% of all cases. The frequency of detection of breast cancer during pregnancy ranges from 1 in 10,000 pregnant women to 1 in 3,000 pregnancies.  The reason that a rare combination of breast cancer and pregnancy is no longer a rarity now, is the older age of childbearing, and that the cohort of patients expands to include those women with breast cancer who were diagnosed during one year after childbirth.Динамика исследований рака молочной железы в последние годы показала, что он является наиболее частой формой опухоли у женщин во время беременности. По данным международных статистических институтов, на эту форму опухоли у женщин моложе 45 лет приходится до 8% всех случаев. Частота выявляемости РМЖ во время беременности колеблется от 1 на 3000 беременных женщин, до 1 на 10000 случаев беременности [1, 2]. Причина того, что ранее достаточно редкое сочетание РМЖ и беременности в настоящее время уже не является редкостью, заключается в более позднем возрасте деторождения, а также в том, что когорта больных расширяется за счет включения в нее и тех женщин, РМЖ у которых обнаружен в течение одного года после родо

Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity

© 2016, Springer Science+Business Media New York.The aggregation and adsorption properties of a new complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide were studied by methods of conductometry, tensiometry, and dynamic light scattering. The critical micelle concentration, size of the aggregates, and adsorption characteristics at the water—air interface were determined. The antimicrobial and antifungal effects were established. The studied properties of the complex were compared with the properties of the ligand and cationic surfactants with a head group of the cyclic and acyclic types. The enhanced aggregation ability of the complex and its improved biological activity were shown

Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity

© 2016, Springer Science+Business Media New York.The aggregation and adsorption properties of a new complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide were studied by methods of conductometry, tensiometry, and dynamic light scattering. The critical micelle concentration, size of the aggregates, and adsorption characteristics at the water—air interface were determined. The antimicrobial and antifungal effects were established. The studied properties of the complex were compared with the properties of the ligand and cationic surfactants with a head group of the cyclic and acyclic types. The enhanced aggregation ability of the complex and its improved biological activity were shown

Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity

© 2016, Springer Science+Business Media New York.The aggregation and adsorption properties of a new complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide were studied by methods of conductometry, tensiometry, and dynamic light scattering. The critical micelle concentration, size of the aggregates, and adsorption characteristics at the water—air interface were determined. The antimicrobial and antifungal effects were established. The studied properties of the complex were compared with the properties of the ligand and cationic surfactants with a head group of the cyclic and acyclic types. The enhanced aggregation ability of the complex and its improved biological activity were shown