70 research outputs found
Academic Integrity: Understanding Essence of Undergraduates’ Plagiarism in Their Research Writing at a Southern Chinese University
In China, plagiarism among undergraduate students has been a protuberant issue preventing the robust development of tertiary education. The purpose of this Interpretative Phenomenological Analysis (IPA) research was to acquire a profound understanding of the essence of the phenomenon through the process of students’ research writing at Shaoyang University (SYU), a southern Chinese University. Employing a step-wise combination of purposive and random sampling techniques, 11 participants were selected to partake in the study’s online, face-to-face, and one-on-one semi-structured interviews. On completion of data analysis, seven themes emerged: poor literacy about plagiarism; few learning experiences related to plagiarism; disapproval of plagiarism with different tolerance levels; difficulties encountered during academic writing; sophistication in detouring the plagiarism detecting tool; reasons for committing plagiarism; and under-evaluation of disciplinary study. Based upon the rich findings, the study proposed a preliminary holistic solution to mitigate plagiarism, with school administration, policy makers, instructors, and students performing and abiding to their respective roles, and with the literacy education related to plagiarism at the center
Effect of secondary oxidation of pre-oxidized coal on early warning value for spontaneous combustion of coal
The indicative ability of a gas indicator for the spontaneous combustion of coal is affected by the secondary oxidation of oxidized coal, from old goafs, entering a new goaf through air leakages. This phenomenon can affect the accuracy of early warning systems regarding the spontaneous combustion of coal in a goaf. In this research, three kinds of coal were selected to carry out a spontaneous combustion simulation experiment in which a temperature-programmed experimental device was used to analyze the behavior of the index gas towards raw coal and oxidized coal, for which the latter was oxidized at 70 ¿C, 90 ¿C, 130 ¿C, and 150 ¿C. The results show that the chain alkane ratio in the secondary oxidation process and the trends of oxygen, CO, and C2H4 concentrations are the same as those in the primary oxidation process. On the other hand, the temperature at which C2H4 initially appears, during secondary oxidation, is lower than in primary oxidation. The CO produced in the early stage of secondary oxidation is greater than the CO produced, at the same temperature, in primary oxidation. In this regard, the usage of C2H4 concentration as an indicator with which to judge the occurrence of the spontaneous combustion of coal would allow for an earlier response. In the secondary oxidation process, the temperature of the extreme value of the alkene ratio appears higher than in primary oxidation. The presence of a higher pre-oxidation temperature and a higher proportion of secondary oxidation gas will affect an indicator’s judgement when the primary oxidation enters the severe oxidation stage. The gas produced by secondary oxidation will affect the early warning of the spontaneous combustion of coal in the coal mine goaf, which should be considered in the establishment of an early warning system.This work was supported by the National Natural Science Foundation of China [52074285].Peer ReviewedObjectius de Desenvolupament Sostenible::8 - Treball Decent i Creixement EconòmicObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i InfraestructuraPostprint (published version
A NIMA-related kinase suppresses the flagellar instability associated with the loss of multiple axonemal structures
CCDC39 and CCDC40 were first identified as causative mutations in primary ciliary dyskinesia patients; cilia from patients show disorganized microtubules, and they are missing both N-DRC and inner dynein arms proteins. In Chlamydomonas, we used immunoblots and microtubule sliding assays to show that mutants in CCDC40 (PF7) and CCDC39 (PF8) fail to assemble N-DRC, several inner dynein arms, tektin, and CCDC39. Enrichment screens for suppression of pf7; pf8 cells led to the isolation of five independent extragenic suppressors defined by four different mutations in a NIMA-related kinase, CNK11. These alleles partially rescue the flagellar length defect, but not the motility defect. The suppressor does not restore the missing N-DRC and inner dynein arm proteins. In addition, the cnk11 mutations partially suppress the short flagella phenotype of N-DRC and axonemal dynein mutants, but do not suppress the motility defects. The tpg1 mutation in TTLL9, a tubulin polyglutamylase, partially suppresses the length phenotype in the same axonemal dynein mutants. In contrast to cnk11, tpg1 does not suppress the short flagella phenotype of pf7. The polyglutamylated tubulin in the proximal region that remains in the tpg1 mutant is reduced further in the pf7; tpg1 double mutant by immunofluorescence. CCDC40, which is needed for docking multiple other axonemal complexes, is needed for tubulin polyglutamylation in the proximal end of the flagella. The CCDC39 and CCDC40 proteins are likely to be involved in recruiting another tubulin glutamylase(s) to the flagella. Another difference between cnk11-1 and tpg1 mutants is that cnk11-1 cells show a faster turnover rate of tubulin at the flagellar tip than in wild-type flagella and tpg1 flagella show a slower rate. The double mutant shows a turnover rate similar to tpg1, which suggests the faster turnover rate in cnk11-1 flagella requires polyglutamylation. Thus, we hypothesize that many short flagella mutants in Chlamydomonas have increased instability of axonemal microtubules. Both CNK11 and tubulin polyglutamylation play roles in regulating the stability of axonemal microtubules
Hydrogeochemical characteristics and water-rock interaction mechanism of coalbed-produced water in the Linfen mining area, eastern margin of Ordos Basin, China
Linfen mining area is one of the main coalbed methane industrial bases in the eastern margin of Ordos Basin, China. However, there are few studies on the hydrogeochemical characteristics of coalbed-produced water in the area. This article collected water samples from 14 coalbed methane drainage wells and analyzed the ionic concentrations, hydrogen and oxygen isotopes, dissolved inorganic carbon isotopes (δ13CDIC) and trace elements. The results showed that the water of Nos. Five and eight coal seams are both Cl-Na type. The total dissolved solids content was high, ranging from 5011.45 mg/L to 23405.39 mg/L. Hydrogen and oxygen isotope data indicated that the coalbed-produced water in the study area is recharged from atmospheric precipitation. In addition, the HCO3− in the produced water of No. Five coal seam and No. Eight coal seam was negatively correlated with δ13CDIC. The value δ13CDIC in the produced water of No. Five coal seam was heavier than that of No. Eight coal seam. These indicate that microbial degradation occurred more strongly in No. Five coal seam than in No. Eight coal seam. The water-rock interaction in the study area was found to be dominated by cation exchange and dissolution filtration through the relationships between anion and cation
The Orbitofrontal Cortex Gray Matter Is Associated With the Interaction Between Insomnia and Depression
Insomnia and depression are highly comorbid symptoms in both primary insomnia (PI) and major depressive disorder (MDD). In the current study, we aimed at exploring both the homogeneous and heterogeneous brain structure alteration in PI and MDD patients. Sixty-five MDD patients and 67 matched PI patients were recruited and underwent a structural MRI scan. The subjects were sub-divided into four groups, namely MDD patients with higher or lower insomnia, and PI patients with higher or lower severe depression. A general linear model was employed to explore the changes in cortical thickness and volume as a result of depression or insomnia, and their interaction. In addition, partial correlation analysis was conducted to detect the clinical significance of the altered brain structural regions. A main effect of depression on cortical thickness was seen in the superior parietal lobe, middle cingulate cortex, and parahippocampal gyrus, while a main effect of insomnia on cortical thickness was found in the posterior cingulate cortex. Importantly, the interaction between depression and insomnia was associated with decreased gray matter volume in the right orbitofrontal cortex, i.e., patients with co-occurring depression and insomnia showed smaller brain volume in the right orbitofrontal cortex when compared to patients with lower insomnia/depression. These findings highlighted the role of the orbitofrontal cortex in the neuropathology of the comorbidity of insomnia and depression. Our findings provide new insights into the understanding of the brain mechanism underlying comorbidity of insomnia and depression
Root Canal Anatomy of Maxillary and Mandibular Teeth
It is a common knowledge that a comprehensive understanding of the complexity of the internal anatomy of teeth is imperative to ensure successful root canal treatment. The significance of canal anatomy has been emphasized by studies demonstrating that variations in canal geometry before cleaning, shaping, and obturation procedures had a greater effect on the outcome than the techniques themselves. In recent years, significant technological advances for imaging teeth, such as CBCT and micro-CT, respectively, have been introduced. Their noninvasive nature allows to perform in vivo anatomical studies using large populations to address the influence of several variables such as ethnicity, aging, gender, and others, on the root canal anatomy, as well as to evaluate, quantitatively and/or qualitatively, specific and fine anatomical features of a tooth group. The purpose of this chapter is to summarize the morphological aspects of the root canal anatomy published in the literature of all groups of teeth and illustrate with three-dimensional images acquired from micro-CT technology.info:eu-repo/semantics/publishedVersio
Enhanced Production of a Novel Cyclic Hexapeptide Antibiotic (NW-G01) by Streptomyces alboflavus 313 Using Response Surface Methodology
NW-G01, produced by Streptomyces alboflavus 313, is a novel cyclic hexapeptide antibiotic with many potential applications, including antimicrobial activity and antitumor agents. This study developed a system for optimizing medium components in order to enhance NW-G01 production. In this study, Plackett-Burman design (PBD) was used to find the key ingredients of medium components, and then response surface methodology (RSM) was implemented to determine their optimal concentrations. The results of PBD revealed that the crucial ingredients related to the production of NW-G01 were (NH4)2SO4, peptone and CaCO3. A prediction model has been built in the experiments of central composite design and response surface methodology, and its validation has been further verified. The optimal medium composition was determined (g/L): corn starch 15, glucose 15, peptone 3.80, (NH4)2SO4 0.06, NaCl 1.5, CaCO3 1.30, MgSO4·7H2O 0.015, K2HPO4·3H2O 0.015, MnCl2·4H2O 0.015, FeSO4·7H2O 0.015, and ZnSO4·7H2O 0.015. Compared with NW-G01 production (5.707 mg/L) in non-optimized fermentation medium, the production of NW-G01 (15.564 mg/L) in optimized fermentation medium had a 2.73-fold increase
Research on Customer Behavioral Intention of Hot Spring Resorts Based on SOR Model: The Multiple Mediation Effects of Service Climate and Employee Engagement
Based on the stimulus–organism–response (SOR) model, this study explored customer behavioral intentions and influencing factors in the service industry, represented by hotels. It studied the servicescape, customer emotions, and customer behavioral intentions. PROCESS analysis was conducted on 305 valid questionnaires collected from hot spring resorts. The study found that servicescape can predict customer behavioral intentions, that customer emotions have a partial mediating effect in the influence of servicescape on customer behavioral intentions, and that service climate and employee engagement have multiple mediation effects in the SOR model. Therefore, the researchers suggest that hotels can improve customer perceptions through decoration and staff management, and thereby develop the hotel in a sustainable way
Research on Customer Behavioral Intention of Hot Spring Resorts Based on SOR Model: The Multiple Mediation Effects of Service Climate and Employee Engagement
Based on the stimulus–organism–response (SOR) model, this study explored customer behavioral intentions and influencing factors in the service industry, represented by hotels. It studied the servicescape, customer emotions, and customer behavioral intentions. PROCESS analysis was conducted on 305 valid questionnaires collected from hot spring resorts. The study found that servicescape can predict customer behavioral intentions, that customer emotions have a partial mediating effect in the influence of servicescape on customer behavioral intentions, and that service climate and employee engagement have multiple mediation effects in the SOR model. Therefore, the researchers suggest that hotels can improve customer perceptions through decoration and staff management, and thereby develop the hotel in a sustainable way
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