Studies of silk protein nanofibers from different origins of silkworms and their physical properties

信州大学博士（工学）学位論文・平成24年9月30日授与（甲第72号）・張 顕華Thesis張 顕華. Studies of silk protein nanofibers from different origins of silkworms and their physical properties. 信州大学, 2012, 98p, 博士論文doctoral thesi

Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds.

Previously, we only apply a traditional Chinese medicine (TCM) Danshen-Chuanxiong-Honghua (DCH) for cardioprotection via anti-inflammation in rats of acute myocardial infarction by occluding coronary artery. Presently, we select not only DCH but also its main absorbed compound ferulic acid (FA) for cerebra protection via similar action of mechanism above in animals of the transient middle cerebral artery occlusion (tMCAO). We investigated whether oral administration of DCH and FA could ameliorate MCAO-induced brain lesions in animals. By using liquid chromatography-tandem mass spectrometry (LC-MS/MS), we analyzed four compounds, including tanshinol, salvianolic acid B, hydroxysafflor yellow A and especially FA as the putative active components of DCH extract in the plasma, cerebrospinal fluid and injured hippocampus of rats with MCAO. In our study, it was assumed that FA played a similar neuroprotective role to DCH. We found that oral pretreatment with DCH (10 or 20 g/kg) and FA (100 mg/kg) improved neurological function and alleviated the infarct volume as well as brain edema in a dose-dependent manner. These changes were accompanied by improved ischemia-induced apoptosis and decreased the inflammatory response. Additionally, chronic treatment with DCH reversed MCAO-induced spatial cognitive deficits in a manner associated with enhanced neurogenesis and increased the expression of brain-derived neurotrophic factor in lesions of the hippocampus. These findings suggest that DCH has the ability to recover cognitive impairment and offer neuroprotection against cerebral ischemic injury via inhibiting microenvironmental inflammation and triggering of neurogenesis in the hippocampus. FA could be one of the potential active compounds

Periodic solutions for second-order Hamiltonian systems with a p-Laplacian

In this paper, by using the least action principle, Sobolev’s inequality and Wirtinger’s inequality, some existence theorems are obtained for periodic solutions of second-order Hamiltonian systems with a p-Laplacian under subconvex condition, sublinear growth condition and linear growth condition. Our results generalize and improve those in the literature

Study on Population Distribution, Morphological Structure and Physiological-Biochemical Characteristics of \u3cem\u3eDactylis glomerata\u3c/em\u3e in Different Geographical Areas of Tianshan Mountains of Xinjiang in China

As one important cool-season grass with high resource value, Dactylis glomerata has many characteristics such as good adaptability, high nutritional value and so on. It is one of the major cultivated species planted in high quality artificial grassland in the world. Xinjiang is one of the major areas have rich germplasm resource of wild Dactylis glomerata, and it is a natural gene pool. In order to protect and make good use of wild plant resources, this study focused on the distribution patterns, distribution regulation, morphological structure and physiological-biochemical characteristics of wild Dactylis glomerata grown in different geographical areas of Tianshan mountain of Xinjiang. It is aims to reveal the effects of geographical space and habitat on the population distribution in, morphological structure and physiological-biochemical characteristics of Dactylis glomerata

Ground state solutions for a class of nonlinear Maxwell-Dirac system

This paper is concerned with the following nonlinear Maxwell-Dirac system\begin{equation*}\begin{cases}\displaystyle-i\sum^{3}_{k=1}\alpha_{k}\partial_{k}u + a\beta u + \omega u-\phi u =F_{u}(x,u),\\-\Delta \phi=4\pi|u|^{2,\\\end{cases} \end{equation*}for $x\in\R^{3}$. The Dirac operator is unbounded from below and above, so the associated energy functional is strongly indefinite. We use the linking and concentration compactness arguments to establish the existence of ground state solutionsfor this system with asymptotically quadratic nonlinearity