New progress in the role of microRNAs in the diagnosis and prognosis of triple negative breast cancer

Triple negative breast cancer is distinguished by its high malignancy, aggressive invasion, rapid progression, easy recurrence, and distant metastases. Additionally, it has a poor prognosis, a high mortality, and is unresponsive to conventional endocrine and targeted therapy, making it a challenging problem for breast cancer treatment and a hotspot for scientific research. Recent research has revealed that certain miRNA can directly or indirectly affect the occurrence, progress and recurrence of TNBC. Their expression levels have a significant impact on TNBC diagnosis, treatment and prognosis. Some miRNAs can serve as biomarkers for TNBC diagnosis and prognosis. This article summarizes the progress of miRNA research in TNBC, discusses their roles in the occurrence, invasion, metastasis, prognosis, and chemotherapy of TNBC, and proposes a treatment strategy for TNBC by interfering with miRNA expression levels

XRD Characterization of Phenol Liquefied Chinese Fir Residues

The amount of wood residue is used as a measurement of the extent of wood liquefaction. Characterization of the residue from wood liquefaction provides a new approach to understand some fundamental aspects of the liquefaction reaction. This paper adopts X-ray diffraction to characterize the changes of groups and mechanism of reaction of the residue crystallinity in the liquefaction process of Chinese Fir. The XRD analysis of liquefaction residue showed that amorphous region is firstly damaged so that the crystallinity could be in the trend of increasing in the liquefaction process of Chinese fir in most cases with the time’s prolonging. However, cellulose crystalline region begins to be destroyed under the higher liquefied temperature (170℃）or in the case of higher P/W (w/w) ratio (5), leading to the relative decreased trend of crystallinity. Key words: Chinese Fir; XRD; Liquefaction; Residu

Effect of Heating Method on Hydrogen Production by Biomass Gasification in Supercritical Water

The glucose as a test sample of biomass is gasified in supercritical water with different heating methods driven by renewable solar energy. The performance comparisons of hydrogen production of glucose gasification are investigated. The relations between temperature raising speed of reactant fluid, variation of volume fraction, combustion enthalpy, and chemical exergy of H2 of the product gases with reactant solution concentration are presented, respectively. The results show that the energy quality of product gases with preheating process is higher than that with no preheating unit for hydrogen production. Hydrogen production quantity and gasification rate of glucose decrease obviously with the increase of concentration of material in no preheating system

Optimization of Resinification of Liquefied Products from Trash Antiseptic Wood

In this study, Anticorrosive fir was liquefied in phenol, and the liquefied wood were used to produce adhesive by resinification. The effect of resinification time, resinification temperature, molar ratio (NaOH/liquefied wood) and molar ratio (methanal/liquefied wood) on resinification was investigated by orthogonal experiments in term of the viscosity, solid content and pH of resinification product. Adhesive produced by resinification was then used for plywood production, and plywood strength was detected to assess adhesive. According to experiment results, the optimal conditions of resimification are as follow: resinification time of 150 min, resinification temperature of 90°C, molar ratio (NaOH/liquefied wood) of 0.5 and molar ratio (methanal/liquefied wood) of 1.8. Using adhesive produced under the optimal conditions to bond plywood, the bonding strength and formaldehyde emission of plywood produced accorded with related national standard (china), and the plywood produced belonged to calss I.Key words: Antiseptic woods; Resinification; Liquefaction; Phenol; Adhesiv

Optimum Research of Hot-Pressing Technology of the Composite Board with Waste Wood and Paper

On the rise of global low-carbon economy with the purpose of leveraging waste wood resources efficiently, waste wood and paper was processed into new type wood-based panels. The hot-pressing technology of the 9 mm composite board with waste wood and paper was studied through an orthogonal experiment, and the effects of resin content, hot-pressing temperature, hot-pressing time and the mass ratio of waste wood and paper were discussed. Results indicated that effects of resin content on the MOR (Modulus of rupture), MOE (modulus of elasticity) and 24h TS (thickness swelling) of the composite board were remarkable, while effects of hot-pressing temperature, hot-pressing time and the mass ratio of waste wood and paper were slight. Based on the quality indicators of MOR, it was found that the optimum condition of hot-pressing for the 9 mm composite board with waste wood and paper was estimated to include resin content of 19%, hot-pressing temperature of 120 °C, hot-pressing time of 12.5min, and the mass ratio of waste wood and paper of 7 to 13. Under these conditions, the composite board could be used as new materials for furniture, interior decoration and packaging.Key words: Waste wood; Waste paper; Composite board; Hot-pressing technolog