29 research outputs found
Comparison of electromagnetic performance of scpm wind power generators with different topologies
This paper focuses on the comparison of electromagnetic performance of the superconducting permanent magnet (SCPM) generators with two different topologies. The torque capabilities of the two generators are first investigated. The peak torque is largely restricted by the material characteristics of the superconducting (SC) and the permanent magnet. The SCPM generators with iron-cored rotor and iron-cored stator topology (IRIST) is superior to the one with iron-cored rotor and air-cored stator topology in terms of torque capability. Furthermore, the flux density, line electromotive force, torque and its torque ripple, and the efficiency of the designed generators are evaluated by using numerical model. The simulation results confirm that IRIST has higher output torque and efficiency with the penalty of higher harmonics and torque ripples
Stator Design Aspects for Permanent Magnet Super-conducting Wind Power Generators
This paper presents an electromagnetic design of a permanent magnet superconducting wind power generator with different stator teeth structures and armature winding arrangements. The main contribution of this paper is that a novel stator configuration is proposed, which is beneficial for superconducting machines. The topology of tapering poles makes it possible for the machine to carry larger current without severe magnetic saturation in the stator teeth. Meantime, the distributed arrangement of wires in the stator slot can reduce the ac loss in the same output power condition. Finite element analysis with commercial software is used to support these results
Ameliorative Effect and Underlying Mechanisms of Total Triterpenoids from Psidium guajava Linn (Myrtaceae) Leaf on High-Fat Streptozotocin-induced Diabetic Peripheral Neuropathy in Rats
Purpose: To investigate whether the total triterpenoids extracted from Psidium Guajava leaves (TTPGL) attenuate the development of diabetic peripheral neuropathy in rats by regulating the NF-ÎșB pathway of the inflammatory process and its signaling mediators.Methods: All the Sprague Dawley rats used were maintained in a clean environment on a 12 h light/12h dark cycle. High-fat feeding and intraperitoneal injection of 40 mg/kg streptozotocin (STZ) were used to induce diabetes in the rats. The rats were randomly divided into 5 groups: diabetic mellitus (DM) group; TTPGL - 30 group, TTPGL - 60 group and TTPGL - 120 group treated by intragastric administration (i.g) with 30, 100 and 120 mg/kg/day TTPGL, respectively. The well-established drug, rosiglitazone (RSG, 3 mg/k/d, i.g.), was used as positive control. Normal rats served as control group. Nerve conduction velocity and sensitive tests were measured on weeks 1, 4 and 8. After 8 weeks administration, expression of pro-inflammatory molecules (TNF - α, IL - 6 and iNOS) and tissue proteins (Akt, IKKα, and NF â ÎșB - p65) were evaluated to assess biochemical changes.Results: Compared to DM group, TTPGL (especially 120 mg / kg dose) treatment improved (p < 0.05) physical functions and provided neuronal protection in high - fat/streptozotocin - induced peripheral neuropathy rats. We found that the expressions of several pro - inflammatory factors such as tumor necrosis factor - α (TNF - α), IL - 6 and inducible nitric oxide synthase (iNOS) were highly suppressed (p < 0.05 or p < 0.01) by TTPGL in sciatic nerve. Mechanism analysis indicated that the ameliorative effect of TTPGL, in part, is through suppression of the expression of pro - inflammatory cytokines by NF - ÎșB pathway mediation.Conclusion: TTPGL offers a potential therapeutic approach for the treatment of diabetic peripheral neuropathy.Keywords: Triterpenoids, Psidium Guajava, Diabetic peripheral neuropathy, Pro inflammatory cytokines, NF-ÎșB pathwa
Effect of Kang Fu Yan capsule on phenol mucilage-induced intrauterine adhesion injury in female rats
Purpose: To investigate the effect of Kang fu yan capsule (KFYC) on phenol mucilage-induced intrauterine adhesion (IUA) in a rat model, and the underlying mechanisms.
Methods: An IUA model was established by injecting 0.06 mL of 25 % phenol mucilage into the uterus of female Sprague-Dawley rats. The IUA model rats (n=59) were randomly divided into 5 groups: IUA group, fuke qianjin tablet group (FKQJT, 0.22 mg/kg), and 3 KFYC groups given different doses of the drug i.e. 0.13, 0.39and 1.17 mg/kg. A group of 10 healthy female rats served as control. After 19 days treatment, blood samples were collected for determination of IL-2 and IL-10 by ELISA, while uterine tissues were subjected to histological examination using hematoxylin and eosin staining (H&E) and Masson staining. Expressions of Notch1, recombination signal binding protein-JK (RBP-JK), a disintegrin and metalloprotease (ADAM)-12, ADAM-15, matrix metalloprotein-9 (MMP-9), and inhibitor of NF-ÎșB (IÄžB) in uterine tissues were determined using RT-qPCR and western blot analysis.
Results: Compared to IUA group, histological results showed reduced inflammatory cell infiltration in rat uterine tissue of KFYC group. Moreover, KFYC significantly reversed uterine fibrosis (p < 0.05). Serum concentrations of IL-2 significantly decreased in KFYC groups (p < 0.05 or p < 0.01), and there was significant increases the serum concentrations of IL-10 in KFYC groups (p < 0.05 or < 0.01), when compared to IUA group. The mRNA and protein expressions of Notch1, RBP-JK, ADAM-12, ADAM-15, MMP-9 were also significantly down-regulated (p < 0.05), while protein expression of IÄžB was upregulated in KFYC group, when compared to IUA group.
Conclusion: KFYC exerts an anti-IUA effect via amelioration of uterine inflammation and fibrosis, probably via a mechanism involving regulation of Notch1/ADAM pathway
Novel Polymer Material for Efficiently Removing Methylene Blue, Cu(II) and Emulsified Oil Droplets from Water Simultaneously
The pollution of water resources has become a worldwide concern. The primary pollutants including insoluble oil, toxic dyes, and heavy metal ions. Herein, we report a polymer adsorbent, named SPCT, to remove the above three contaminants from water simultaneously. The preparation process of SPCT contains two steps. Firstly, a hydrogel composed of sulfonated phenolic resin (SMP) and polyethyleneimine (PEI) was synthesized using glutaraldehyde (GA) as the crosslinking agent, and the product was named SPG. Then SPCT was prepared by the reaction between SPG and citric acid (CA) at 170 â C. SPCT exhibited an excellent performance for the removal of methylene blue (MB) and Cu(II) from aqueous solution. For a solution with a pollutant concentration of 50 mg L−1, a removal efficiency of above 90% could be obtained with a SPCT dosage of 0.2 g L−1 for MB, or a SPCT dosage of 0.5 g L−1 for Cu(II), respectively. SPCT also presented an interesting wettability. In air, it was both superhydrophilic and superoleophilic, and it was superoleophobic underwater. Therefore, SPCT could successfully separate oil-in-water emulsion with high separation efficiency and resistance to oil fouling. Additionally, SPCT was easily regenerated by using dilute HCl solution as an eluent. The outstanding performance of SPCT and the efficient, cost-effective preparation process highlight its potential for practical applications
The Influence of Cyclic Loading on the Mechanical Properties of Well Cement
The cyclic loading generated by injection and production operations in underground gas storage facilities can lead to fatigue damage to cement sheaths and compromise the integrity of wellbores. To investigate the influence of cyclic loading on the fatigue damage of well cement, uniaxial and triaxial loading tests were conducted at different temperatures, with maximum cyclic loading intensity ranging from 60% to 90% of the ultimate strength. Test results indicate that the compressive strength and elastic modulus of well cement subjected to monotonic loading under high-temperature and high-pressure (HTHP) testing conditions were 14â21% lower than those obtained under ambient testing conditions. The stressâstrain curve exhibits stressâstrain hysteresis loops during cyclic loading tests, and the plastic deformation capacity is enhanced at HTHP conditions. Notably, a higher intensity of cyclic loading results in more significant plastic strain in oil-well cement, leading to the conversion of more input energy into dissipative energy. Furthermore, the secant modulus of well cement decreased with cycle number, which is especially significant under ambient test conditions with high loading intensity. Within 20 cycles of cyclic loading tests, only the sample tested at a loading intensity of 90% ultimate strength under an ambient environment failed. For samples that remained intact after 20 cycles of cyclic loading, the compressive strength and stressâstrain behavior were similar to those obtained before cyclic loading. Only a slight decrease in the elastic modulus is observed in samples cycled with high loading intensity. Overall, oil-well cement has a longer fatigue life when subjected to HTHP testing conditions compared to that tested under ambient conditions. The fatigue life of well cement increases significantly with a decrease in loading intensity and can be predicted based on the plastic strain evolution rate