79 research outputs found
Active spintronic-metasurface terahertz emitters with tunable chirality
The ability to manipulate the electric-field vector of broadband terahertz
waves is essential for applications of terahertz technologies in many areas,
and can open up new possibilities for nonlinear terahertz spectroscopy and
coherent control. Here, we propose a novel laser-driven terahertz emitter,
consisting of metasurface-patterned magnetic multilayer heterostructures. Such
hybrid terahertz emitters can combine the advantages of spintronic emitters for
being ultrabroadband, efficient and flexible, as well as those of metasurfaces
for the unique capability to manipulate terahertz waves with high precision and
degree of freedom. Taking a stripe-patterned metasurface as an example, we
demonstrate the generation of broadband terahertz waves with tunable chirality.
Based on experimental and theoretical studies, the interplay between the
laser-induced spintronic-origin currents and the metasurface-induced transient
charges/currents are investigated, revealing the strong influence on the device
functionality originated from both the light-matter interactions in individual
metasurface units and the dynamic coupling between them. Our work not only
offers a flexible, reliable and cost-effective solution for chiral terahertz
wave generation and manipulation, but also opens a new pathway to
metasurface-tailored spintronic devices for efficient vector-control of
electromagnetic waves in the terahertz regime
Surface Structure of Protonated R-Sapphire (11Ì…02) Studied by Sum-Frequency Vibrational Spectroscopy
Sum frequency vibrational spectroscopy was used to study the protonated R-plane (1{bar 1}02 ) sapphire surface. The OH stretch vibrational spectra show that the surface is terminated with three hydroxyl moieties, two from AlOH{sub 2} and one from Al{sub 2}OH functional groups. The observed polarization dependence allows determination of the orientations of the three OH species. The results suggest that the protonated sapphire (1{bar 1}02 ) surface differs from an ideal stoichimetric termination in a manner consistent with previous X-ray surface diffraction (crystal truncation rod) studies. However, in order to best explain the observed hydrogenbonding arrangement, surface oxygen spacing determined from the X-ray diffraction study requires modification
Solitary beam propagation in a nonlinear optical resonator enables high-efficiency pulse compression and mode self-cleaning
Generating intense ultrashort pulses with high-quality spatial modes is
crucial for ultrafast and strong-field science. This can be accomplished by
controlling propagation of femtosecond pulses under the influence of Kerr
nonlinearity and achieving stable propagation with high intensity. In this
work, we propose that the generation of spatial solitons in periodic layered
Kerr media can provide an optimum condition for supercontinuum generation and
pulse compression using multiple thin plates. With both the experimental and
theoretical investigations, we successfully identify these solitary modes and
reveal a universal relationship between the beam size and the critical
nonlinear phase. Space-time coupling is shown to strongly influence the
spectral, spatial and temporal profiles of femtosecond pulses. Taking advantage
of the unique characters of these solitary modes, we demonstrate single-stage
supercontinuum generation and compression of femtosecond pulses from initially
170 fs down to 22 fs with an efficiency ~90%. We also provide evidence of
efficient mode self-cleaning which suggests rich spatial-temporal
self-organization processes of laser beams in a nonlinear resonator
Time Course of Gene Expression Profiling in the Liver of Experimental Mice Infected with Echinococcus multilocularis
BACKGROUND: Alveolar echinococcosis (AE) is a severe chronic parasitic disease which behaves like a slow-growing liver cancer. Clinical observations suggest that the parasite, Echinococcus multilocularis (E. multilocularis) influences liver homeostasis and hepatic cell metabolism. However, this has never been analyzed during the time course of infection in the common model of secondary echinococcosis in experimental mice. METHODOLOGY/PRINCIPAL FINDINGS: Gene expression profiles were assessed using DNA microarray analysis, 1, 2, 3 and 6 months after injection of E. multilocularis metacestode in the liver of susceptible mice. Data were collected at different time points to monitor the dynamic behavior of gene expression. 557 differentially expressed genes were identified at one or more time points, including 351 up-regulated and 228 down-regulated genes. Time-course analysis indicated, at the initial stage of E. multilocularis infection (month 1-2), that most of up-regulated pathways were related to immune processes and cell trafficking such as chemokine-, mitogen-activated protein kinase (MAPK) signaling, and down-regulated pathways were related to xenobiotic metabolism; at the middle stage (month 3), MAPK signaling pathway was maintained and peroxisome proliferator-activated receptor (PPAR) signaling pathway emerged; at the late stage (month 6), most of up-regulated pathways were related to PPAR signaling pathway, complement and coagulation cascades, while down-regulated pathways were related to metabolism of xenobiotics by cytochrome P450. Quantitative RT-PCR analysis of a random selection of 19 genes confirmed the reliability of the microarray data. Immunohistochemistry analysis showed that proliferating cell nuclear antigen (PCNA) was increased in the liver of E. multilocularis infected mice from 2 months to 6 months. CONCLUSIONS: E. multilocularis metacestode definitely exerts a deep influence on liver homeostasis, by modifying a number of gene expression and metabolic pathways. It especially promotes hepatic cell proliferation, as evidenced by the increased PCNA constantly found in all the experimental time-points we studied and by an increased gene expression of key metabolic pathways
Nonrelativistic and nonmagnetic control of terahertz charge currents via electrical anisotropy in RuO2 and IrO2
Precise and ultrafast control over photo-induced charge currents across
nanoscale interfaces could lead to important applications in energy harvesting,
ultrafast electronics, and coherent terahertz sources. Recent studies have
shown that several relativistic mechanisms, including inverse spin-Hall effect,
inverse Rashba-Edelstein effect and inverse spin-orbit-torque effect, can
convert longitudinally injected spin-polarized currents from magnetic materials
to transverse charge currents, thereby harnessing these currents for terahertz
generation. However, these mechanisms typically require external magnetic
fields and suffer from low spin-polarization rates and low efficiencies of
relativistic spin-to-charge conversion. In this work, we present a novel
nonrelativistic and nonmagnetic mechanism that directly utilizes the
photo-excited high-density charge currents across the interface. We demonstrate
that the electrical anisotropy of conductive oxides RuO2 and IrO2 can
effectively deflect injected charge currents to the transverse direction,
resulting in efficient and broadband terahertz radiation. Importantly, this new
mechanism has the potential to offer much higher conversion efficiency compared
to previous methods, as conductive materials with large electrical anisotropy
are readily available, whereas further increasing the spin-Hall angle of
heavy-metal materials would be challenging. Our new findings offer exciting
possibilities for directly utilizing these photo-excited high-density currents
across metallic interfaces for ultrafast electronics and terahertz
spectroscopy
Spatially homogeneous few-cycle compression of Yb lasers via all-solid-state free-space soliton management
The high power and variable repetition-rate of Yb femtosecond lasers makes them very attractive for ultrafast science. However, for capturing sub-200 fs dynamics, efficient, high-fidelity and high-stability pulse compression techniques are essential. Spectral broadening using an all-solid-state free-space geometry is particularly attractive, as it is simple, robust and low-cost. However, spatial and temporal losses caused by spatio-spectral inhomogeneities have been a major challenge to date, due to coupled space-time dynamics associated with unguided nonlinear propagation. In this work, we use all-solid-state free-space compressors to demonstrate compression of 170 fs pulses at a wavelength of 1030nm from a Yb:KGW laser to ∼9.2 fs, with a highly spatially homogeneous mode. This is achieved by ensuring that the nonlinear beam propagation in periodic layered Kerr media occurs in spatial soliton modes, and by confining the nonlinear phase through each material layer to less than 1.0 rad. A remarkable spatio-spectral homogeneity of ∼0.87 can be realized, which yields a high efficiency of >50% for few-cycle compression. The universality of the method is demonstrated by implementing high-quality pulse compression under a wide range of laser conditions. The high spatiotemporal quality and the exceptional stability of the compressed pulses are further verified by high-harmonic generation. Our predictive method offers a compact and cost-effective solution for high-quality few-cycle-pulse generation from Yb femtosecond lasers, and will enable broad applications in ultrafast science and extreme nonlinear optics.
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Numerical study of blast wave propagation through granular materials subjected to buried blasts
Blast wave propagation in dry sand subjected to a buried charge is numerically investigated using a charge-sand stratified configuration wherein the mass ratio between sand and charge (M/C) spans over two decades. The detonation of the central charge and the sand dynamics are modeled by the FEM-DEM method. The findings reveal the pressure-profile associated with the blast wave undergoes marked shape transition as the expansion fans catch up with the incident blast wave. The blast propagation and the associated pressure-profiles depend on the coupling between the sand and the detonation products in the central gas pocket which is in turn influenced by a variety of structural parameters. Specifically, as the M/C increases from 21 to 436, the average velocity of the blast wave decreases by 22.2%. Furthermore, a blast compaction model of sand is proposed to account for the coupling effect and justify the influences arising from key-structural parameters
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