ELLE & IL : enantioselective liquid-liquid extraction and ionic liquids

L'extraction liquide-liquide énantiosélective (ELLE) consiste en l'extraction d'un énantiomère à partir d'un mélange racémique par transfert entre deux phases liquides. Cette technologie est très prometteuse pour l'obtention des composés énantiopurs et devient l'objet d'une forte attention les dernières années grâce au développement de l'équipement approprié qui permet de réduire le temps et le prix de la séparation des énantiomères. L'objectif essentiel pour l'introduction d'ELLE dans le monde industriel est la découverte d'hôtes chiraux fiables, peu chers, durables, sélectifs et applicables à une large gamme de substances chirales. Dans ce travail, la possibilité d'effectuer l'ELLE dans un milieu ionique chiral a été vérifiée. De nombreux nouveaux liquides ioniques chiraux ont été préparés pour jouer le rôle des hôtes chiraux. Le meilleur exemple montre un excès énantiomérique de 30% et une sélectivité opérationnelle de 1,97. Ceci représente le premier exemple d'ELLE utilisant les liquides ioniques chiraux et sans usage d'ions métalliques.Enantioselective liquid-liquid extraction (ELLE) is an implementation of the extraction of one enantiomer from a racemic mixture by the transfer between two liquid phases. This technology is very promising for obtaining enantiopure compounds and becomes the object of much attention in recent years after the development of appropriate equipment that reduces the time and cost of the separation of enantiomers. The major objective for the successful introduction of ELLE to industrial world is the discovery of reliable, inexpensive and durable chiral hosts selective for a wide range of chiral substances. In this work the possibility of performing ELLE in chiral ionic liquids environment was verified. Many new chiral ionic liquids were prepared to play the role of chiral hosts. The best example shows enantiomeric excess of 30% and operational selectivity of 1.97. This represents the first example of using chiral ionic liquids in ELLE and without metallic ions

Irreducible triangulations of the once-punctured torus

A triangulation of a surface with fixed topological type is called irreducible if no edge can be contracted to a vertex while remaining in the category of simplicial complexes and preserving the topology of the surface. A complete list of combinatorial structures of irreducible triangulations is made by hand for the once-punctured torus, consisting of exactly 297 non-isomorphic triangulations.Plan Andaluz de Investigación (Junta de Andalucía)Ministerio de Ciencia e Innovació

Peptide Synthesis in Ionic Liquids (PEPSIL): All You Need is in the Toolbox!

This personal account describes our studies regarding peptide synthesis in ionic liquids (PEPSIL). In addition, we summarize our experiments in which the use of ionic liquids gives simple and promising access to unnatural amino acids in an enantiomerically enriched form. Extension of PEPSIL method to complex structures such as cyclopeptides is also discussed. Some of these cyclopeptides are the direct precursors of bioactive and pharmaceutical compounds

Grants by Legislation of the RF Subjects for Citizens having Children (Omsk region and Khanty-Mansi autonomous district - Yugra)

The article is devoted to the analysis of Khanty-Mansi autonomous region - Yugra and the Omsk Region normative-legal acts in the social security sphere of citizens having children. The most important differences were distinguished in the social security levels of the families of these subjects of the Russian Federation

POLITICAL-ECONOMY COMPONENTS OF ADMINISTRATION OF SYSTEM PROMOTE TO CORPORATION HUMAN RESOURCES

Corporation human resources consist of general, private and special components. Function of corporation human resources have to based on scientific management and conform interests of corporation and personal. Reproduction of special human resources depending on level of social responsibility and optimal development corporation system of motives and incentives