(S)-N-Phenyl-tert-butane­sulfinamide

The asymmetric unit of the title compound, C10H15NOS, contains two independent mol­ecules with similar conformations. In the crystal, mol­ecules are linked in a head-to-tail fashion by N—H⋯O hydrogen bonds into chains running along the b axis. The absolute configuration was assigned on the basis of known chirality of the parent compound

An efficient system for the Pd-catalyzed cross-coupling of amides and aryl chlorides

A catalyst based on a new biarylphosphine ligand (3) for the Pd-catalyzed cross-coupling reactions of amides and aryl chlorides is described. This system shows the highest turnover frequencies reported to date for these reactions, especially for aryl chloride substrates bearing an ortho substituent. An array of amides and aryl chlorides were successfully reacted in good to excellent yields.National Institutes of Health (U.S.) (Grant GM-58160)Merck & Co., Inc.BASFChemetallNippon Chemical Industrial Co.William Asbornsen Albert Memorial Fund (Fellowship)University of Aarhus. Department of ChemistryUniversity of Aarhus. Interdisciplinary Nanoscience CentreChina Scholarship CouncilNational Natural Science Foundation (China) (Grant 20672088

(R)-N-(Biphenyl-4-yl)-tert-butane­sulfinamide

In the title compound, C16H19NOS, the dihedral angle between the two aromatic rings is 38.98 (8)°. The crystal structure is stabilized by N—H⋯O hydrogen bonds, which link neighbouring mol­ecules into chains running parallel to the a axis

(R)-N-(3-Meth­oxy­phen­yl)-tert-butane­sulfinamide

The title compound, C11H17NO2S, was obtained by the reaction of (R)-tert-butane­sulfinamide with 3-meth­oxy­phenyl bromide in toluene. In the crystal, mol­ecules inter­act head-to-tail through N—H⋯O and C—H⋯O hydrogen bonds, forming one-dimensional chains parallel to the a axis

Substituent effects and mechanism elucidation of enantioselective sulfoxidation catalyzed by vanadium Schiff base complexes

The effects of substituents of the Schiff base ligands on oxo-vanadium-catalyzed enantioselective sulfoxidation were first systematically studied, and a rational mechanism of enantioselective sulfoxidation based on our experimental data and the reported data is proposed

Thermodynamic studies on mechanism of chiral resolution by liquid chromatography

Chiral recognition is an important part of molecular recognition. Studies of mechanistic aspects of chiral resolution by liquid chromatography are helpful to optimize chromatographic conditions, to design novel chiral stationary phases and to understand chiral recogniton mechanisms. In this paper, the methodologies for deriving corresponding thermodynamic parameters in the chiral resolution processes by linear or nonlinear chromatography are reviewed. The meaning of correlative parameters is explained. The applications of these parameters in the studies of mechanistic aspects of retentions and chiral resolutions by liquid chromatography are expatiated, and corresponding research prospects are put forward

Draft genome sequence of the mulberry tree Morus notabilis

Human utilization of the mulberry–silkworm interaction started at least 5,000 years ago and greatly influenced world history through the Silk Road. Complementing the silkworm genome sequence, here we describe the genome of a mulberry species Morus notabilis. In the 330-Mb genome assembly, we identify 128 Mb of repetitive sequences and 29,338 genes, 60.8% of which are supported by transcriptome sequencing. Mulberry gene sequences appear to evolve ~3 times faster than other Rosales, perhaps facilitating the species’ spread worldwide. The mulberry tree is among a few eudicots but several Rosales that have not preserved genome duplications in more than 100 million years; however, a neopolyploid series found in the mulberry tree and several others suggest that new duplications may confer benefits. Five predicted mulberry miRNAs are found in the haemolymph and silk glands of the silkworm, suggesting interactions at molecular levels in the plant–herbivore relationship. The identification and analyses of mulberry genes involved in diversifying selection, resistance and protease inhibitor expressed in the laticifers will accelerate the improvement of mulberry plants