Synthesis of C2-Symmetric Bisphosphines and Their Application in Enantioselective Transition Metal Catalysis

C2-symmetric bisphosphine ligands (with a dioxolane backbone) have been synthesized by using corresponding chiral bromo-substituted hydrobenzoin derivatives in two steps with moderate yields. The last step for desired bisphosphines defined the electronic and steric properties of the chelating atoms by the treatment of aryl or alkyl substituted chlorophosphine compounds in the presence of a base. These synthesized ligands have been evaluated in different catalytic reactions. The first application has been the palladiumcatalyzed enantioselective allylic alkylation which is regarded as a remarkable reaction for forming enantioselective carbon-carbon bond (up to 63 % ee and 98 % chemical yield). The ruthenium-catalyzed enantioselective transfer hydrogenation reaction has been the second application for the evaluating of the catalysts (up to > 99 % conversion with no enantioselectivity). This work is licensed under a Creative Commons Attribution 4.0 International License

Morphometric risk factors effects on anterior cruciate ligament injury

Objectives: This study aims to compare the morphometric differences between patients with and without an anterior cruciate ligament (ACL) injury and to investigate the anatomical risk factors associated with ACL injury. Patients and methods: Between February 2020 and February 2022, a total of 100 patients (57 males, 43 females; mean age: 36.2 +/- 6.8 years; range, 18 to 45 years) who were operated for isolated non-contact ACL tear as the patient group and a total of 100 healthy individuals (58 males, 42 females; mean age: 35.0 +/- 6.9 years; range, 18 to 45 years) without an ACL tear as the control group were included. Magnetic resonance imaging scans of the knee joint were included in the study. Morphological variables of the ACL, distal femur, proximal tibia, and menisci were measured. Results: The mean ACL inclination angle and medial meniscus bone angle were 37.7 +/- 3.8 and 20.2 +/- 2.9 in the patient group and 48.1 +/- 3.3 and 25.0 +/- 2.9 in the control group. According to the results of multivariate analysis, those with small ACL inclination angle and medial meniscus bone angle were more likely to have ACL tear (odds ratio: 0.128, intraclass correlation coefficient: 0.038-0.430, p= 0.001). Conclusion: Small ACL inclination angle and medial meniscus bone angle can be a risk factor for ACL tear

Testicular Ischemia Caused by Incarcerated Inguinal Hernia in Infants: Incidence, Conservative treatment procedure, and Follow-up

Purpose: Testicular ischemia and necrosis, especially in the infant age, may result from incarcerated inguinal hernia. Duration of ischemia is a significant factor for the affected testicle. We aimed to present a case series on the conservative management in the testicular ischemia caused by incarcerated inguinal hernia

Adult Onset Langerhans Cell Histiocytosis

Langerhans cell histiocytosis (LCH) is a rare disease characterized by clonal and neoplastic proliferation of Langerhans cells. It is most commonly seen in children but can be seen at any age. Clinical findings depend on the organ system involved. The diagnosis of LCH is made histopathologically. The treatment is planned according to the organ system of the disease, the prevalence of the lesions and the presence of specific organ dysfunction. We aimed to discuss the clinical, radiological and histapatological findings of a 33-year-old man with femoral involvement at adulthood and discuss the current literature

Morphological Features of Major Submarine Landslides of Marmara Sea Using Multibeam Data

Recent bathymetric surveys help us to understand morphological features of the Marmara Sea. Marmara Sea has unique and complex morphological features and active tectonics. In this study, morphologic features of major submarine landslides of the Marmara Sea were studied using advanced visualization and geomatic systems (digital terrain models, DTM; geographic-information systems, GIS; image-processing systems; high-resolution seismic and bathymetric data)

Morphological features of major submarine landslides of Marmara Sea using multibeam data

Recent bathymetric surveys help us to understand morphological features of the Marmara Sea. Marmara Sea has unique and complex morphological features and active tectonics. In this study, morphologic features of major submarine landslides of the Marmara Sea were studied using advanced visualization and geomatic systems (digital terrain models, DTM; geographic-information systems, GIS; image-processing systems; high-resolution seismic and bathymetric data)