51 research outputs found
NeuralPCI: Spatio-temporal Neural Field for 3D Point Cloud Multi-frame Non-linear Interpolation
In recent years, there has been a significant increase in focus on the
interpolation task of computer vision. Despite the tremendous advancement of
video interpolation, point cloud interpolation remains insufficiently explored.
Meanwhile, the existence of numerous nonlinear large motions in real-world
scenarios makes the point cloud interpolation task more challenging. In light
of these issues, we present NeuralPCI: an end-to-end 4D spatio-temporal Neural
field for 3D Point Cloud Interpolation, which implicitly integrates multi-frame
information to handle nonlinear large motions for both indoor and outdoor
scenarios. Furthermore, we construct a new multi-frame point cloud
interpolation dataset called NL-Drive for large nonlinear motions in autonomous
driving scenes to better demonstrate the superiority of our method. Ultimately,
NeuralPCI achieves state-of-the-art performance on both DHB (Dynamic Human
Bodies) and NL-Drive datasets. Beyond the interpolation task, our method can be
naturally extended to point cloud extrapolation, morphing, and auto-labeling,
which indicates its substantial potential in other domains. Codes are available
at https://github.com/ispc-lab/NeuralPCI.Comment: Accepted by CVPR 2023. Project Page:
https://dyfcalid.github.io/NeuralPC
Strong magnon-magnon coupling in an ultralow damping all-magnetic-insulator heterostructure
Magnetic insulators such as yttrium iron garnets (YIGs) are of paramount
importance for spin-wave or magnonic devices as their ultralow damping enables
ultralow power dissipation that is free of Joule heating, exotic magnon quantum
state, and coherent coupling to other wave excitations. Magnetic insulator
heterostructures bestow superior structural and magnetic properties and house
immense design space thanks to the strong and engineerable exchange interaction
between individual layers. To fully unleash their potential, realizing low
damping and strong exchange coupling simultaneously is critical, which often
requires high quality interface. Here, we show that such a demand is realized
in an all-insulator thulium iron garnet (TmIG)/YIG bilayer system. The ultralow
dissipation rates in both YIG and TmIG, along with their significant spin-spin
interaction at the interface, enable strong and coherent magnon-magnon coupling
with a benchmarking cooperativity value larger than the conventional
ferromagnetic metal-based heterostructures. The coupling strength can be tuned
by varying the magnetic insulator layer thickness and magnon modes, which is
consistent with analytical calculations and micromagnetic simulations. Our
results demonstrate TmIG/YIG as a novel platform for investigating hybrid
magnonic phenomena and open opportunities in magnon devices comprising
all-insulator heterostructures.Comment: 45 pages, 18 figures, and 2 table
TORC1 determines Fab1 lipid kinase function at signaling endosomes and vacuoles
Acknowledgments: We thank Lars Langemeyer for feedback, all members from the Ungermann lab for discussions, and Kathrin Auffarth, Angela Perz, and Malika Jaquenoud for expert technical assistance. This work was supported by the DFG (UN111/10-1 to C.U.), the Canton of Fribourg (to J.D. and C.D.V.), and the Swiss National Science Foundation (310030_166474/184671 to C.D.V. and 310030_184781 and 316030_177088 to J.D.). Z.C. received support from a travel stipend of the Boehringer Ingelheim Fonds. P.C.M. received additional support from the graduate program of the Collaborative Research Center 944 (SFB 944) and Department of Biology/Chemistry Osnabrück. E.E. received a fellowship of FWO Vlaanderen, Belgium (SB-FWO 1S06419N). Author Contributions: Z.C. and P.C.M. conducted all experiments on Fab1 localization and function; R.H. conducted experiments on development and analysis of the Sch91–183 probe; R.N., Z.H., M.-P.P.-G., and J.D. did the phosphorylation assays and analyses; and E.E. and J.W. conceived and performed the initial Sch9 mapping. T.N. and C.J.S. did the lipid analysis of the mutant alleles. J.G. analyzed microcopy data with Z.C. C.D.V. and C.U. conceived the study and wrote the manuscript with support of J.W.Peer reviewedPublisher PD
The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Ageing constitutes the most important risk factor for all major chronic ailments, including malignant, cardiovascular and neurodegenerative diseases. However, behavioural and pharmacological interventions with feasible potential to promote health upon ageing remain rare. Here we report the identification of the flavonoid 4,4′- dimethoxychalcone (DMC) as a natural compound with anti-ageing properties. External DMC administration extends the lifespan of yeast, worms and flies, decelerates senescence of human cell cultures, and protects mice from prolonged myocardial ischaemia. Concomitantly, DMC induces autophagy, which is essential for its cytoprotective effects from yeast to mice. This pro-autophagic response induces a conserved systemic change in metabolism, operates independently of TORC1 signalling and depends on specific GATA transcription factors. Notably, we identify DMC in the plant Angelica keiskei koidzumi, to which longevity- and health-promoting effects are ascribed in Asian traditional medicine. In summary, we have identified and mechanistically characterised the conserved longevity-promoting effects of a natural anti-ageing drug
Nanostructured materials for Li-ion batteries with enhanced performance
Lithium-ion batteries (LIBs) are rechargeable batteries that use lithium ions for the storage and release of energy. LIBs have gained significant attention and widespread use in various applications due to their high energy density, long cycle life and easy accessibility. By utilizing nanostructured materials as electrodes or electrolytes, lithium-ion batteries can benefit from expanded electrochemically active surfaces, increased electronic and ionic conductivities, and improved mechanical properties. These advantages contribute to superior battery performance when compared to bulk materials. The objective of this thesis is to design and synthesize innovative nanostructured materials for LIBs, with the aim of enhancing electrochemical performance and addressing the limitations of bulk structures. Three different creatively designed nanostructured systems have been proposed and utilized for electrodes and electrolytes, all of which demonstrate enhanced electrochemical properties and battery performance. Furthermore, through the study of the battery mechanism, the peculiar nanostructures of these synthesized materials are regarded as playing a crucial role in achieving their superior performance.(SC - Sciences) -- UCL, 202
Effect of aspirin on blood pressure in hypertensive patients: a systematic review and meta-analysis
Abstract Introduction Aspirin is widely used for secondary prevention in patients with hypertension. However, previous studies mainly focused on the preventive effects of aspirin, and there has been a lack of reliable evidence on whether taking aspirin affects blood pressure This study aimed to investigate whether aspirin would affect the blood pressure in patients with hypertension. Methods PubMed, Cochrane database, Embase, Scopus and Medline databases were searched until September 2023. For continuous variables (e.g., blood pressure reduction), the mean difference (MD) was selected as the effect magnitude indices. We used the Cochrane Collaboration’s Risk of Bias tool to assess the risk of bias. Result A total of five studies were included, comprising 20,312 patients. We found that aspirin did not affect SBP (MD = -0.78, 95% CI: − 2.41, 0.84). A similar result was found for DBP (MD = -0.86, 95% CI: − 2.14, 0.42). Conclusion This study showed no significant difference in blood pressure between the aspirin and control groups, suggesting that aspirin does not affect blood pressure
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