294 research outputs found

    Magnetothermoelectric DC conductivities from holography models with hyperscaling factor in Lifshitz spacetime

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    We investigate an Einstein-Maxwell-Dilaton-Axion holographic model and obtain two branches of a charged black hole solution with a dynamic exponent and a hyperscaling violation factor when a magnetic field presents. The magnetothermoelectric DC conductivities are then calculated in terms of horizon data by means of holographic principle. We find that linear temperature dependence resistivity and quadratic temperature dependence inverse Hall angle can be achieved in our model. The well-known anomalous temperature scaling of the Nernst signal and the Seebeck coefficient of cuprate strange metals are also discussed.Comment: 1+23 pages, 4 figures, references adde

    Variational Quantum Metrology with Loschmidt Echo

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    By utilizing quantum mechanical effects, such as superposition and entanglement, quantum metrology promises higher precision than the classical strategies. It is, however, practically challenging to realize the quantum advantages. This is mainly due to the difficulties in engineering non-classical probe state and performing nontrivial measurement in practise, particularly with a large number of particles. Here we propose a scalable scheme with a symmetrical variational quantum circuit which, same as the Loschmidt echo, consists of a forward and a backward evolution. We show that in this scheme the quantum Fisher information, which quantifies the precision limit, can be efficiently obtained from a measurement signal of the Loschmidt echo. We experimentally implement the scheme on an ensemble of 10-spin quantum processor and successfully achieves a precision near the theoretical limit which outperforms the standard quantum limit with 12.4 dB. The scheme can be efficiently implemented on various noisy intermediate-scale quantum devices which provides a promising routine to demonstrate quantum advantages

    3-Methyl­sulfanyl-5-phenyl-4H-1,2,4-triazol-4-amine–water (6/1)

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    In the title compound, 6C9H10N4S·H2O, the dihedral angle between the five-membered triazole ring and the phenyl ring is 44.33 (16)°. The solvent water molecule is disordered about a special position with symmetry and its occupancy cannot be greater than 0.1667. The crystal structure is stabilized by inter­molecular N—H⋯N and C–H⋯N hydrogen bonds

    MicroRNA-275 and its target vitellogenin-2 are crucial in ovary development and blood digestion of Haemaphysalis longicornis

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    Background: The hard tick Haemaphysalis longicornis is widely distributed in eastern Asia, New Zealand and Australia and is considered the major vector of Theileria and Babesia, harmful parasites to humans and animals. Female ticks need successful blood meals to complete the life-cycle. Therefore, elucidation of the underlying molecular mechanisms of H. longicornis development and reproduction is considered important for developing control strategies against the tick and tick-borne pathogens. Methods: Luciferase assays were used to identify the targets of micro RNA miR-275 in vitro. RNAi of Vitellogenin (Vg) was used in phenotype rescue experiments of ticks with miR-275 inhibition, and these analyses were used to identify the authentic target of miR-275 in vivo. The expression of miR-275 in different tissues and developmental stages of ticks was assessed by real-time PCR. To elucidate the functions of miR-275 in female ticks, we injected a miR-275 antagomir into female ticks and observed the phenotypic changes. Statistical analyses were performed with GraphPad5 using Student’s t-test. Results: In this study, we identified Vg-2 as an authentic target of miR-275 both in vitro and in vivo by luciferase assays and phenotype rescue experiments. miR-275 plays the regulatory role in a tissue-specific manner and differentially in developmental stages. Silencing of miR-275 resulted in blood digestion problems, substantially impaired ovary development and significantly reduced egg mass (P < 0.0001). Furthermore, RNAi silencing of Vg-2 not only impacted the blood meal uptake (P < 0.05) but also the egg mass (P < 0.05). Significant rescue was observed in miR-275 knockout ticks when RNAi was applied to Vg-2. Conclusion: To our knowledge, this study is the first demonstration that miR-275 targets Vg-2 in H. longicornis and regulates the functions of blood digestion and ovary development. These findings improve the molecular understanding of tick development and reproduction
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