Cacería para autoconsumo durante la pandemia de COVID-19

En este trabajo, se hipotetiza el periodo de aislamiento, la inmovilización y la migración inversa que sucedidos durante la pandemia del COVID-19 (años 2020 y 2021) incrementaron la capacidad de caza de las comunidades Matsigenkas asentadas en el Parque Nacional del Manu (PN Manu). Para esto, evaluamos los cambios en los patrones del volumen de extracción de la caza a través de un monitoreo participativo utilizando el modelo de monitoreo de la intensidad de cacería. Se evidenció que hubo un incremento de la capacidad de caza de las comunidades nativas. Los volúmenes más altos de extracción y el mayor incremento del número de cazadores, esfuerzo y área de cacería se dieron en el periodo 2020 – 2021, cuando las medidas de aislamiento e inmovilización fueron establecidas. Sin embargo, hubo una disminución de los indicadores para la temporada 2021 – 2022, año en que se flexibilizaron las medidas de aislamiento y se dio la reactivación económica, permitiendo que las personas retornaran a sus actividades económicas y educativas fuera del PN Manu. Se debe considerar que los efectos de solo un año de pandemia sobre los medios de subsistencia de las comunidades pudieron afectar la abundancia de la fauna silvestre, donde el mono maquisapa y mono choro (especies vulnerables) tuvieron altos incrementos de extracción. Por otro lado, nuestros resultados indicarían que el buen estado de conservación del PN Manu permitió la provisión de alimentos a las comunidades durante la pandemia. Se recomienda la planificación de programas que mitiguen los efectos negativos de pandemias o eventos semejantes, además se señala la importancia de medir el grado de resiliencia de las principales especies de caza, ya que el incremento de caza también podría tener efectos sobre la seguridad alimentaria de estas comunidades

Integration of the EventIndex with other ATLAS systems

The ATLAS EventIndex System, developed for use in LHC Run 2, is designed to index every processed event in ATLAS, replacing the TAG System used in Run 1. Its storage infrastructure, based on Hadoop, necessitates revamping how information in this system relates to other ATLAS systems. In addition, the scope of this new application is different from that of the TAG System. It will store fewer derived quantities, but store more indexes since the fundamental mechanisms for retrieving these indexes will be better integrated into all stages of processing, allowing more events from later stages of processing to be indexed than was possible with the previous system. Connections with other systems are fundamentally critical to assess dataset completeness, identify data duplication, and check data integrity, but also needed to enhance user and system interfaces accessing information in EventIndex. This presentation will give an overview of the ATLAS systems involved, the relevant metadata, and describe the technologies we are deploying to complete these connections

The Small Metal-Binding Protein SmbP Improves the Expression and Purification of the Recombinant Antitumor-Analgesic Peptide from the Chinese Scorpion <i>Buthus martensii</i> Karsch in <i>Escherichia coli</i>

We have recently shown that SmbP, the small metal-binding protein of Nitrosomonas europaea, can be employed as a fusion protein to express and purify recombinant proteins and peptides in Escherichia coli. SmbP increases solubility, allows simple, one-step purification through affinity chromatography, and provides superior final yields due to its low molecular weight. In this work, we report for the first time the use of SmbP to produce a recombinant peptide with anticancer activity: the antitumor-analgesic peptide (BmK-AGAP), a neurotoxin isolated from the venom of the Chinese scorpion Buthus martensii Karsch. This peptide was expressed in Escherichia coli SHuffle for correct, cytoplasmic, disulfide bond formation and tagged with SmbP at the N-terminus to improve its solubility and allow purification using immobilized metal affinity chromatography. SmbP_BmK-AGAP was found in the soluble fraction of the cell lysate. After purification and removal of SmbP by digestion with enterokinase, 1.8 mg of pure and highly active rBmK-AGAP was obtained per liter of cell culture. rBmK-AGAP exhibited antiproliferative activity on the MCF-7 cancer cell line, with a half-maximal inhibitory concentration value of 7.24 μM. Based on these results, we considered SmbP to be a suitable carrier protein for the production of recombinant, biologically active BmK-AGAP. We propose that SmbP should be an attractive fusion protein for the expression and purification of additional recombinant proteins or peptides that display anticancer activities

Additional file 2: of KB-R7943 reduces 4-aminopyridine-induced epileptiform activity in adult rats after neuronal damage induced by neonatal monosodium glutamate treatment

Results of two-way ANOVA test (in p values) applied to determinate the interactions between treatments on the electrographic parameters evaluated in this work. (DOCX 16 kb

Matemática Discreta - MA265 - 202102

Este curso es parte de la formación general de los estudiantes de Ingeniería de Sistemas de Información, de Ingeniería de Software y de Ciencias de la Computación, dirigido a los estudiantes de tercer ciclo, es de carácter teórico y desarrolla la competencia de Razonamiento Cuantitativo en el nivel 1. El alumno podrá interpretar, representar, comunicar y utilizar información en situaciones de contexto real. Incluye calcular, razonar, emitir juicios de valor y tomar decisiones con base en la información cuantitativa. Se realizarán cuatro actividades para reforzar esta competencia y en el examen final se evaluará esta competencia con cuatro puntos del mismo, para poder verificar si el alumno la logró. En el aprendizaje de Matemática Discreta el estudiante interioriza la relevancia de las ideas abstractas y se siente motivado a aplicarlas en computación

The ATLAS EventIndex: architecture, design choices, deployment and first operation experience

The EventIndex is the complete catalogue of all ATLAS events, keeping the references to all files that contain a given event in any processing stage. It replaces the TAG database, which had been in use during LHC Run 1. For each event it contains its identifiers, the trigger pattern and the GUIDs of the files containing it. Major use cases are event picking, feeding the Event Service used on some production sites, and technical checks of the completion and consistency of processing campaigns. The system design is highly modular so that its components (data collection system, storage system based on Hadoop, query web service and interfaces to other ATLAS systems) could be developed separately and in parallel during LS1. The EventIndex is in operation for the start of LHC Run 2. This paper describes the high-level system architecture, the technical design choices and the deployment process and issues. The performance of the data collection and storage systems, as well as the query services, are also reported