A clustering approach to detect faults with multi-component degradations in aircraft fuel systems

Accurate fault diagnosis and prognosis can significantly increase the safety and reliability of engineering systems and also reduce the maintenance costs. There is very limited relative research reported on the fault diagnosis of a complex system with multi-component degradation. The Complex Systems (CS) problem, which features multiple components simultaneously and nonlinearly interacting with each other and corresponding environment on multiple levels, has become an essential challenge in system engineering. In CS, even a single component degradation could cause misidentification of the fault severity level and lead to serious consequences. This paper introduces a new test rig to simulate multi-component degradations of the aircraft fuel system. A data analysis approach based on machine learning classification of both the time and frequency domain features is then proposed to detect and identify the fault severity level of CS with multi-component degradation. Results show that a) the fault can be sensitively detected with an accuracy > 99%; b) the severity of fault can be identified with an accuracy of 100%

A machine learning-based clustering approach to diagnose multi-component degradation of aircraft fuel systems

Accurate fault diagnosis and prognosis can significantly reduce maintenance costs, increase the safety and availability of engineering systems that have become increasingly complex. It has been observed that very limited researches have been reported on fault diagnosis where multi-component degradation are presented. This is essentially a challenging Complex Systems problem where features multiple components interacting simultaneously and nonlinearly with each other and its environment on multiple levels. Even the degradation of a single component can lead to a misidentification of the fault severity level. This paper introduces a new test rig to simulate the multi-component degradation of the aircraft fuel system. A machine learning-based data analytical approach based on the classification of clustering features from both time and frequency domains is proposed. The scope of this framework is the identification of the location and severity of not only the system fault but also the multi-component degradation. The results illustrate that (a) the fault can be detected with accuracy > 99%; (b) the severity of fault can be identified with an accuracy of almost 100%; (c) the degradation level can be successfully identified with the R-square value > 0.9

Opioids in clinical practice

The treatment of pain improves quality of life. Opioids are commonly prescribed painkillers. The side effectsof opioids depend on the route of administration, dosage, drug metabolism, comorbid diseases and thepatient’s general condition. Despite many beneficial effects, opioids can lead to increased mortality in heartfailure, myocardial infarction, pulmonary oedema, and COPD. This article reviews specific uses of opioidmedications. Opioids induce immunosuppression, and may undergo drug-drug interactions, especiallyduring polytherapy or polypragmasia

Opioidy w praktyce klinicznej

Leczenie bólu przyczynia się do poprawy jakości życia. Opioidy są powszechnie przepisywanymi lekami przeciwbólowymi. Działania niepożądane stosowania opioidów zależą od drogi podania, dawkowania, metabolizmu leków, chorób współistniejących i ogólnego stanu pacjenta. Pomimo wielu korzystnych efektów, opioidy mogą prowadzić do zwiększonej śmiertelności w przypadku wystąpienia niewydolności serca, zawału serca, obrzęku płuc i POChP. W niniejszym artykule omówiono poszczególne zastosowania leków opioidowych. Opioidy wywołują immunosupresję i mogą wchodzić w interakcje lekowe, zwłaszcza podczas politerapii lub polipragmazji