EDITORIAL: Intraoperative Quality Control of Carotid Endarterectomy

Von Dr. J. Utsc

Crossover in Growth Law and Violation of Superuniversality in the Random Field Ising Model

We study the nonconserved phase ordering dynamics of the d = 2, 3 random field Ising model, quenched to below the critical temperature. Motivated by the puzzling results of previous work in two and three di- mensions, reporting a crossover from power-law to logarithmic growth, together with superuniversal behavior of the correlation function, we have undertaken a careful investigation of both the domain growth law and the autocorrelation function. Our main results are as follows: We confirm the crossover to asymptotic logarithmic behavior in the growth law, but, at variance with previous findings, the exponent in the preasymptotic power law is disorder-dependent, rather than being the one of the pure system. Furthermore, we find that the autocorre- lation function does not display superuniversal behavior. This restores consistency with previous results for the d = 1 system, and fits nicely into the unifying scaling scheme we have recently proposed in the study of the random bond Ising model.Comment: To be published in Physical Review

Test of Local Scale Invariance from the direct measurement of the response function in the Ising model quenched to and to below TCT_C

In order to check on a recent suggestion that local scale invariance [M.Henkel et al. Phys.Rev.Lett. {\bf 87}, 265701 (2001)] might hold when the dynamics is of Gaussian nature, we have carried out the measurement of the response function in the kinetic Ising model with Glauber dynamics quenched to $T_C$ in $d=4$, where Gaussian behavior is expected to apply, and in the two other cases of the $d=2$ model quenched to $T_C$ and to below $T_C$, where instead deviations from Gaussian behavior are expected to appear. We find that in the $d=4$ case there is an excellent agreement between the numerical data, the local scale invariance prediction and the analytical Gaussian approximation. No logarithmic corrections are numerically detected. Conversely, in the $d=2$ cases, both in the quench to $T_C$ and to below $T_C$, sizable deviations of the local scale invariance behavior from the numerical data are observed. These results do support the idea that local scale invariance might miss to capture the non Gaussian features of the dynamics. The considerable precision needed for the comparison has been achieved through the use of a fast new algorithm for the measurement of the response function without applying the external field. From these high quality data we obtain $a=0.27 \pm 0.002$ for the scaling exponent of the response function in the $d=2$ Ising model quenched to below $T_C$, in agreement with previous results.Comment: 24 pages, 6 figures. Resubmitted version with improved discussions and figure

Nonlinear response and fluctuation dissipation relations

A unified derivation of the off equilibrium fluctuation dissipation relations (FDR) is given for Ising and continous spins to arbitrary order, within the framework of Markovian stochastic dynamics. Knowledge of the FDR allows to develop zero field algorithms for the efficient numerical computation of the response functions. Two applications are presented. In the first one, the problem of probing for the existence of a growing cooperative length scale is considered in those cases, like in glassy systems, where the linear FDR is of no use. The effectiveness of an appropriate second order FDR is illustrated in the test case of the Edwards-Anderson spin glass in one and two dimensions. In the second one, the important problem of the definition of an off equilibrium effective temperature through the nonlinear FDR is considered. It is shown that, in the case of coarsening systems, the effective temperature derived from the second order FDR is consistent with the one obtained from the linear FDR.Comment: 24 pages, 6 figure

Does the Presence of an Iliac Aneurysm Affect Outcome of Endoluminal AAA Repair? An Analysis of 336 Cases

AbstractObjective: to determine whether the presence of an iliac aneurysm compromises outcome of endovascular exclusion of AAA and to ascertain the fate of the iliac aneurysmal sac.Patients and methods: between April 1997 and March 2001, data on 336 consecutive patients undergoing endovascular repair for AAA were entered in a prospective database. Suitability for endovascular repair was assessed by preoperative contrast-enhanced computed tomography. A maximum common iliac artery (CIA) diameter ≥20mm was defined as iliac aneurysm. Patients with and without iliac aneurysms were compared to early (immediate conversion or perioperative death) and late failure (increase in aneurysm diameter or persisting graft-related endoleak, or late AAA rupture or conversion).Results: fifty-nine patients (18%) had iliac aneurysms, 19 were bilateral, for a total of 78 aneurysmal iliac arteries (median diameter 23mm; range 20–50mm). A distal seal was achieved by landing in 33 external iliac arteries, in 20 ectatic CIAs, and in 25 normal CIAs. Operating time differed significantly between patients with and without CIA aneurysms (153±71 vs 123±55min,p =0.0001), whereas no statistically significant differences were found with respect to early and late failure (2% vs 3%, p=0.5 and 14% vs 8%, p=0.11, respectively). There were no cases of buttock or colon necrosis. At a median follow-up of 14 months (range 0–46; i.q.r. 7–27 months) common iliac diameter decreased ≥2mm in 49 cases, remained stable in 25, and increased ≥2mm in 3.Conclusion: the presence of iliac aneurysm rendered endoluminal AAA repair more complex but did not affect feasibility and long-term outcome of the procedure. In our experience internal iliac exclusion was never associated with significant morbidity. These data may be useful when considering endovascular repair in high-risk patients with challenging anatomy

Role of Duplex Scan in Endoleak Detection After Endoluminal Abdominal Aortic Aneurysm Repair

AbstractObjective: to validate the role of duplex scan in endoleak detection in postoperative surveillance of endoluminal abdominal aneurysm repair (EAAR). Patients and methods between April 1997 and March 1999, 103 patients were eligible for duplex and computed tomography (CT) scan after EAAR. Mean follow-up was 8 months (range 1–24 months). The study protocol comprised concurrent examination with colour-duplex and CT scan at 1, 6, and 12 months after EAAR, for a total of 198 concurrent examinations. All duplex scan examinations were performed by two vascular surgeons with the same machine (ATL HDI 3000). Interobserver agreement in endoleak detection (κ=1) and in type of endoleak (κ=0.7) was evaluated in 50 random duplex examinations. Endoleak detection was examined comparatively in duplex and CT scan, the latter being the gold standard. Sensitivity and specificity tests together with negative- and positive-predictive values (NPV and PPV) were calculated. Results duplex scan was not feasible in one patient. On CT scan the endoleak rate was 4% at one month, 3% at 6 months, and 4% at one year. Overall, CT scan detected 12 endoleaks. With respect to endoleak detection, duplex scan revealed a great ability in ruling out false-negative results (sensitivity 91.7%, NPV 99.4%), but overestimated the presence of endoleak (specificity 98.4%, PPV 78.6%). Regarding type of endoleak, the ability of duplex scan to identify the source of endoleak was low (sensitivity 66.7%). Conclusions duplex scan, if validated, appears to be a reliable means for excluding the presence of endoleak after EAAR

Fluctuation-Dissipation relations far from Equilibrium

In this Article we review some recent progresses in the field of non-equilibrium linear response theory. We show how a generalization of the fluctuation-dissipation theorem can be derived for Markov processes, and discuss the Cugliandolo-Kurchan \cite{Cugliandolo93} fluctuation dissipation relation for aging systems and the theorem by Franz {\it et. al.} \cite{Franz98} relating static and dynamic properties. We than specialize the subject to phase-ordering systems examining the scaling properties of the linear response function and how these are determined by the behavior of topological defects. We discuss how the connection between statics and dynamics can be violated in these systems at the lower critical dimension or as due to stochastic instability.Comment: 18 pages, 10 figure

Effects of an external drive on the fluctuation-dissipation relation of phase-ordering systems

The relation between the autocorrelation $C(t,t_w)$ and the integrated linear response function $\chi(t,t_w)$ is studied in the context of the large-N model for phase-ordering systems subjected to a shear flow. In the high temperature phase $T>T_c$ a non-equilibrium stationary state is entered which is characterized by a non-trivial fluctuation-dissipation relation $\chi (t-t_w)=\tilde \chi(C(t-t_w))$. For quenches below $T_c$ the splitting of the order parameter field into two statistically independent components, responsible for the stationary $C^{st}(t-t_w)$ and aging $C^{ag}(t/t_w)$ part of the autocorrelation function, can be explicitly exhibited in close analogy with the undriven case. In the regime $t-t_w\ll t_w$ the same relation $\chi (t-t_w)=\tilde \chi (C^{st}(t-t_w))$ is found between the response and $C^{st}(t-t_w)$, as for $T>T_c$ . The aging part of $\chi (t,t_w)$ is negligible for $t_w\to \infty$, as without drive, resulting in a flat $\chi (C)$ in the aging regime $t-t_w\gg t_w$.Comment: 8 pages, 2 figure