KARTAGENER’S SYNDROME: A CASE REPORT

Kartagener’s syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive inherited disease, and is characterized by the triad of chronic sinusitis, bronchiectasis, and situs inversus. This paper reports the case of a 27-year-old female presenting with dyspnea on medium exertion, accompanied by chronic cough, non-productive or with clear expectoration. She had recurrent pneumonia until 15 years of age and underwent a lobectomy in the lower lobe of the left lung, probably due to bronchiectasis. Chest computed tomography showed situs inversus totalis, signs of previous surgical manipulation, and mild bronchial thickening. Computed tomography of the paranasal sinuses showed signs of chronic sinusitis due to a probable ciliary kinesis disorder. These finding suggest the diagnosis of Kartagener’s syndrome. The prognosis reveals a slow rate of decline in lung function. However, repeated or chronic infections can negatively influence the quality of life of these patients.Kartagener’s syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive inherited disease, and is characterized by the triad of chronic sinusitis, bronchiectasis, and situs inversus. This paper reports the case of a 27-year-old female presenting with dyspnea on medium exertion, accompanied by chronic cough, non-productive or with clear expectoration. She had recurrent pneumonia until 15 years of age and underwent a lobectomy in the lower lobe of the left lung, probably due to bronchiectasis. Chest computed tomography showed situs inversus totalis, signs of previous surgical manipulation, and mild bronchial thickening. Computed tomography of the paranasal sinuses showed signs of chronic sinusitis due to a probable ciliary kinesis disorder. These finding suggest the diagnosis of Kartagener’s syndrome. The prognosis reveals a slow rate of decline in lung function. However, repeated or chronic infections can negatively influence the quality of life of these patients

Gastroenterite Eosinofílica: Um relato de caso

Introdução: As Gastroenterites Eosinofílicas (GE) são doenças crônicas imunomediadas caracterizadas histologicamente por um aumento de eosinófilos nas diferentes camadas teciduais do trato gastrointestinal. As GE se referem a um grupo de condições, incluindo a esofagite eosinofílica (EE), a gastrite eosinofílica (GE), a enterite eosinofílica (ENE) e a colite eosinofílica (CE). A prevalência da GE nos Estados Unidos é estimada em 22 a 28 por 100.000 pessoas e é maior em crianças <5 anos. Quando presentes em adultos, são mais comuns na terceira e quinta décadas de vida, tendo proporção igual entre homens e mulheres. Sugere-se um componente alérgico na fisiopatogenia das doenças, com 50 a 70% dos pacientes apresentando condições atópicas concomitantes.Método: relatamos um caso de uma paciente com gastroenterite eosinofílica, baseado na história da paciente e registro de prontuário.Resultado: O caso descrito demonstra a importância do conhecimento dos critérios clínicos para o diagnóstico dessa patologia. Conclusão: O tratamento equivocado prolonga o quadro clínico e potencializa o aparecimento de possíveis complicações com impacto negativo na qualidade de vida

KARTAGENER’S SYNDROME: A CASE REPORT

Kartagener’s syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive inherited disease, and is characterized by the triad of chronic sinusitis, bronchiectasis, and situs inversus. This paper reports the case of a 27-year-old female presenting with dyspnea on medium exertion, accompanied by chronic cough, non-productive or with clear expectoration. She had recurrent pneumonia until 15 years of age and underwent a lobectomy in the lower lobe of the left lung, probably due to bronchiectasis. Chest computed tomography showed situs inversus totalis, signs of previous surgical manipulation, and mild bronchial thickening. Computed tomography of the paranasal sinuses showed signs of chronic sinusitis due to a probable ciliary kinesis disorder. These finding suggest the diagnosis of Kartagener’s syndrome. The prognosis reveals a slow rate of decline in lung function. However, repeated or chronic infections can negatively influence the quality of life of these patients.Kartagener’s syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive inherited disease, and is characterized by the triad of chronic sinusitis, bronchiectasis, and situs inversus. This paper reports the case of a 27-year-old female presenting with dyspnea on medium exertion, accompanied by chronic cough, non-productive or with clear expectoration. She had recurrent pneumonia until 15 years of age and underwent a lobectomy in the lower lobe of the left lung, probably due to bronchiectasis. Chest computed tomography showed situs inversus totalis, signs of previous surgical manipulation, and mild bronchial thickening. Computed tomography of the paranasal sinuses showed signs of chronic sinusitis due to a probable ciliary kinesis disorder. These finding suggest the diagnosis of Kartagener’s syndrome. The prognosis reveals a slow rate of decline in lung function. However, repeated or chronic infections can negatively influence the quality of life of these patients