Evaluation of treatment outcomes in children with maxillofacial vascular tumors: Cohort study

Background. The variety of the clinical features of vascular tumors in the maxillofacial area limits the choice of method and is able to make difficulties in the treatment. The combined method of treatment proposed by the authors (vascular sclerotherapy with concurrent propranolol intake) demonstrates high efficacy, lack of invasiveness, shortening the rehabilitation period and less side effects. Objective. The aim of the study was to increase the effectiveness of conservative treatment of vascular tumors of the maxillofacial area in young children by combining the method of sclerotherapy and taking proprono-lol. Methods. In a cohort study, the results of treatment of 80 children aged 2 months to 2 years with vascular tumors of the maxillofacial region (ICD-10: D18.0) were evaluated. A comparison was made of the results in 2 groups of children who were treated with different methods: combined (n =40; main group; sclerotherapy and taking propranolol) and propranolol monotherapy (n =40; comparison group). Analysis of the data obtained in the main group and the comparison group led to the development of the criteria for evaluating the treatment results: good (regression of vascular tumors and the absence of a cosmetic defect), satisfactory (reduction of vascular tumors by 2/3 or more with maintaining cosmetic defect) and unsatisfactory (gross cosmetic defect) in terms of changes in the volume of tumor, the diameter of the supply vessels and the values of the linear velocity of blood flow according to ultrasound data. Results. Subjects treated by the combined treatment had a significant regression of vascular tumors in the maxillofacial area compared with the comparison group: reduction of the tumor volume, diameter of the supply vessels and linear blood flow velocity according ultrasound data reached zero after 6 months from the start of combined treatment — 6 months earlier than in the comparison group (p <0.001). Conclusion. According to the results of the study, the advantage of the author’s method over the traditional method was demonstrated, which resulted in a reduction in the duration of treatment, a decrease in the risk as well as in a degree of complications. © 2019 Paediatrician Publishers, LLC. All rights reserved

Significance of ultrasound research in the diagnostics of formations of the maxilofacial region

In this article shows efficiency of ultrasound diagnostics of volume formations of the maxillofacial regionВ статье показана эффективность ультразвуковой диагностики объемных образований челюстно-лицевой области

THE CLEANING SYSTEM OF I CIRCUIT SODIUM OF UNIT IV OF BELOYARSKAYA NUCLEAR POWER PLANT

This article discusses the cleaning system of I circuit sodium of IV unit of the Beloyarskaya nuclear power plant.В данной статье рассматривается система очистки натрия I контура IV энергоблока Белоярской атомной станции

EFFICIENT USE OF RESOURCES BY THE EXAMPLE OF CHAMBER ELECTRIC RESISTANCE FURNACE

The report examines the design and basic specifications of chamber electric resistance EOS 6,3. The operation of the furnace, it identified the main shortcomings, offered effective measures for modernization and reducing energy consumption.В докладе рассмотрены конструкция и основные технические характеристики камерной электропечи сопротивления СНЗ 6,3. Проанализирована работа печи, выявлены основные ее недостатки, предложены эффективные мероприятия для технического и снижения потребления энергии

Estimation of social network user's influence in a given area of expertise

Nowadays social networks are frequently used to express personal opinion on a topic of interest. Some users' opinion has more informational influence than others do. These users are called influential users. There are services that allow evaluating how popular and influential users are; however, any information on evaluation methods is proprietary and represents know-how of such software services. Furthermore, most services could not provide extensive data on the influential users within the specified area of knowledge. This article proposes the method of evaluating a user influence index within a social network in a given area of expertise

The structure of maxillofacial trauma above children in Yekaterinburg

The purpose of the study is to describe the structure of injuries of the maxillofacial region among children in Yekaterinburg for the period from 2020 to 2022.Цель исследования — описать структуру травм челюстно-лицевой области среди детей г. Екатеринбурга за период с 2020 по 2022 г

Текстурные и КТ-признаки в дифференциальном диагнозе гиперваскулярных нейроэндокринных опухолей поджелудочной железы и метастазов почечно-клеточного рака: диагностическая модель

Objective: to develop a diagnostic model that includes CT and radiomic features for the differential diagnosis of pancreatic neuroendocrine tumors (PNETs) G1 and G2 and pancreatic renal cell carcinoma (RCC) metastases.Material and Methods. 78 patients with 79 hypervascular PNETs and 17 patients with 24 pancreatic RCC metastases who underwent pancreatic resection and histological verification were selected in the study. All the patients underwent preoperative contrast enhanced CT (CECT). We assessed tumor attenuation, composition (cystic/solid), homogeneity (homogeneous/heterogeneous), calcification and presence of the main pancreatic duct (MPD) dilation. We calculated lesion-to-parenchyma contrast (LPC), relative tumor enhancement ratio (RTE) and extracted 52 texture features for arterial phase of CECT. Qualitative and texture features were compared between PNETs and pancreatic RCC metastasis. The selection of predictors for the logistic model was carried out in 2 successive stages: 1) selection of predictors based on one-factor logistic models, the selection criterion was p &lt; 0.2; 2) selection of predictors using L2 regularization (LASSO regression after standardization of independent variables). The selected predictors were included in a logistic regression model without interactions, the coefficients of which were estimated using the maximum likelihood method with a penalty of 0.8.Results. There was no difference in composition, homogeneity (homogeneous/heterogeneous) and presence of the MPD dilation between groups. We did not find calcification in pancreatic RCC metastasis, in contrast to the PNETs (9% contained calcifications). After selection, the LCR, CONVENTIONAL_HUmin, GLCM_Correlation, NGLDM_Coarseness were included in the final diagnostic model, which showed a sensitivity and specificity of 95.8%; 62% in the prediction of pancreatic RCC metastases.Conclusion. The diagnostic model developed on the basis of texture and CT-features has high sensitivity (95.8%) with moderate specificity (62%), which allows it to be used in complex diagnostic cases to determine the patient's treatment tactics.Цель исследования: разработать диагностическую модель, включающую КТ-характеристики и показатели радиомики для дифференциальной диагностики нейроэндокринных опухолей поджелудочной железы (ПНЭО) G1 и G2 и метастазов почечно-клеточного рака (ПКР).Материал и методы. В исследование были отобраны 78 пациентов с 79 гиперваскулярными ПНЭО и 17 пациентов с 24 метастазами ПКР, которым была выполнена резекция поджелудочной железы с гистологической верификацией. Всем пациентам перед операцией была проведена КТ с контрастным усилением. Мы оценивали плотность опухоли, структуру (кистозная/солидная), гомогенность (гомогенная/гетерогенная), кальцификацию и наличие расширения главного протока поджелудочной железы (ГПП). Мы рассчитали отношение плотности опухоли к плотности паренхимы (LPC) и относительный коэффициент контрастирования опухоли (RTE) и вычислили 52 текстурных показателя для артериальной фазы КТ-исследования. Качественные и текстурные характеристики сравнивали между ПНЭО и метастазами ПКР. Отбор предикторов в логистическую модели осуществлялся в 2 последовательных этапа: 1) отбор предикторов на основе однофакторных логистических моделей, критерием отбора служило p &lt; 0.2; 2) отбор предикторов с помощью L2-регуляризации (LASSO-регрессия после стандартизации независимых переменных). Отобранные предикторы включались в логистическую регрессионную модель без взаимодействий, коэффициенты которой рассчитывались с использованием метода максимального праводоподобия со штрафом 0,8.Результаты. Не было различий в структуре, гомогенности (гомогенные/гетерогенные) и наличии дилатации ГПП между группами. Мы не обнаружили кальцификации при метастазах ПКР, в отличие от ПНЭО. После отбора LCR, CONVENTIONAL_HUmin, GLCM_Correlation, NGLDM_Coarseness были включены в окончательную диагностическую модель, которая показала чувствительность и специфичность 95.8%; 62% в прогнозировании метастазов ПКР.Заключение. Разработанная на основании текстурных и КТ-признаков диагностическая модель обладает высокой чувствительностью (95.8%) при умеренной специфичности (62%), что позволяет использовать ее при сложных диагностических случаях для определения тактики лечения пациента