Meta-Governance Framework to Guide the Establishment of Mass Collaborative Learning Communities

UIDB/00066/2020 ERASMUS +619130-EPP-1-2020-1-FR-EPPKA2-CBHE-JPThe application of mass collaboration in different areas of study and work has been increasing over the last few decades. For example, in the education context, this emerging paradigm has opened new opportunities for participatory learning, namely, “mass collaborative learning (MCL)”. The development of such an innovative and complementary method of learning, which can lead to the creation of knowledge-based communities, has helped to reap the benefits of diversity and inclusion in the creation and development of knowledge. In other words, MCL allows for enhanced connectivity among the people involved, providing them with the opportunity to practice learning collectively. Despite recent advances, this area still faces many challenges, such as a lack of common agreement about the main concepts, components, applicable structures, relationships among the participants, as well as applicable assessment systems. From this perspective, this study proposes a meta-governance framework that benefits from various other related ideas, models, and methods that together can better support the implementation, execution, and development of mass collaborative learning communities. The proposed framework was applied to two case-study projects in which vocational education and training respond to the needs of collaborative education–enterprise approaches. It was also further used in an illustration of the MCL community called the “community of cooks”. Results from these application cases are discussed.publishersversionpublishe

An Organizational and Governance Model to Support Mass Collaborative Learning Initiatives

Funding text 1 This study was supported by the Center of Technology and Systems (CTS-UNINOVA). Funding text 2 Fundação para a Ciência e Tecnologia (project UIDB/00066/2020) and European Commission ERASMUS + through grant n° 2020-1-FR01-KA202-080231 ED-EN HUB.Mass collaboration can bring about major transformative changes in the way people can work collectively. This emerging paradigm promises significant economic and social benefits and enhanced efficiency across a range of sectors, including learning and education. Accordingly, this article introduces, demonstrates in use, and evaluates an organizational and governance model designed to provide guidance and execution support for the implementation and operation of mass collaborative learning initiatives. The design science research process is adopted to guide the design and development of the proposed model. The model stands on three streams of work, addressing key aspects and elements that have a supporting influence on community learning: (i) identify the positive and negative factors in existing and active examples of mass collaboration; (ii) adopt contributions of collaborative networks in terms of structural and behavioral aspects; and (iii) establish adequate learning assessment indicators and metrics. The model is used for a case study in which vocational education and training meet the needs of collaborative education–enterprise approaches. Initially, the validation of the model is verified by the partners and stakeholders of a particular project in the area of education–enterprises relations to ensure that it is sufficiently appropriate for applications in a digital platform developed by such projects. The three first steps of (the proposed) applicability evaluation (adequacy, feasibility, and effectiveness) are then performed. The positive results gained from model validation and its applicability evaluation in this project indicate that not only is the model fairly adequate, feasible, and effective for applications in the developed digital platform but also that it has a high potential for utilization in supporting and directing the creation, implementation, and operation of mass collaborative learning initiatives. Although the validation was carried out in the context of a single project, in fact, it was based on a large “focus group” of experts involved in this international initiative, which is in accordance with the Design Science Research method. Thus, this article reflects a kind of applied research of a socio-technical nature, aiming to find guidelines and practical solutions to the specific issues, problems, and concerns of mass collaborative learning initiatives.publishersversionpublishe

Review of technology‐supported multimodal solutions for people with dementia

Funding Information: This research was partially funded by FAITH project (H2020?SC1?DTH?2019?875358), CARELINK project (AAL?CALL?2016?049), and Funda??o para a Ci?ncia e Tecnologia through the program UIDB/00066/2020 (CTS?Center of Technology and Systems).Acknowledgments: The authors acknowledge the European Commission for its support and partial funding; the partners of the research project FAITH project (H2020?SC1?DTH?2019?875358); and CARELINK, AAL?CALL?2016?049 funded by AAL JP and co?funded by the European Commission and National Funding Authorities of Ireland, Belgium, Portugal, and Switzerland. Partial support also comes from Funda??o para a Ci?ncia e Tecnologia through the program UIDB/00066/2020 (CTS?Center of Technology and Systems). Funding Information: Acknowledgments: The authors acknowledge the European Commission for its support and partial funding; the partners of the research project FAITH project (H2020‐SC1‐DTH‐2019‐875358); and CARELINK, AAL‐CALL‐2016‐049 funded by AAL JP and co‐funded by the European Commission and National Funding Authorities of Ireland, Belgium, Portugal, and Switzerland. Partial support also comes from Fundação para a Ciência e Tecnologia through the program UIDB/00066/2020 (CTS—Center of Technology and Systems). Funding Information: Funding: This research was partially funded by FAITH project (H2020‐SC1‐DTH‐2019‐875358), CARELINK project (AAL‐CALL‐2016‐049), and Fundação para a Ciência e Tecnologia through the program UIDB/00066/2020 (CTS—Center of Technology and Systems). Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.The number of people living with dementia in the world is rising at an unprecedented rate, and no country will be spared. Furthermore, neither decisive treatment nor effective medicines have yet become effective. One potential alternative to this emerging challenge is utilizing supportive technologies and services that not only assist people with dementia to do their daily activities safely and independently, but also reduce the overwhelming pressure on their caregivers. Thus, for this study, a systematic literature review is conducted in an attempt to gain an overview of the latest findings in this field of study and to address some commercially available supportive technologies and services that have potential application for people living with dementia. To this end, 30 potential supportive technologies and 15 active supportive services are identified from the literature and related websites. The technologies and services are classified into different classes and subclasses (according to their functionalities, capabilities, and features) aiming to facilitate their understanding and evaluation. The results of this work are aimed as a base for designing, integrating, developing, adapting, and customizing potential multimodal solutions for the specific needs of vulnerable people of our societies, such as those who suffer from different degrees of dementia.publishersversionpublishe

Dysregulation of Connexin expression plays a pivotal role in psoriasis

Background: Psoriasis, a chronic inflammatory disease affecting 2–3% of the population, is characterised by epidermal hyperplasia, a sustained pro-inflammatory immune response and is primarily a T-cell driven disease. Previous work determined that Connexin26 is upregulated in psoriatic tissue. This study extends these findings. Methods: Biopsies spanning psoriatic plaque (PP) and non-involved tissue (PN) were compared to normal controls (NN). RNA was isolated and subject to real-time PCR to determine gene expression profiles, including GJB2/CX26, GJB6/CX30 and GJA1/CX43. Protein expression was assessed by immunohistochemistry. Keratinocytes and fibroblasts were isolated and used in 3D organotypic models. The pro-inflammatory status of fibroblasts and 3D cultures was assessed via ELISA and RnD cytokine arrays in the presence or absence of the connexin channel blocker Gap27. Results: Connexin26 expression is dramatically enhanced at both transcriptional and translational level in PP and PN tissue compared to NN (>100x). In contrast, CX43 gene expression is not affected, but the protein is post-translationally modified and accumulates in psoriatic tissue. Fibroblasts isolated from psoriatic patients had a higher inflammatory index than normal fibroblasts and drove normal keratinocytes to adopt a “psoriatic phenotype” in a 3D-organotypic model. Exposure of normal fibroblasts to the pro-inflammatory mediator peptidoglycan, isolated from Staphylococcus aureus enhanced cytokine release, an event protected by Gap27. Conclusion: dysregulation of the connexin26:43 expression profile in psoriatic tissue contributes to an imbalance of cellular events. Inhibition of connexin signalling reduces pro-inflammatory events and may hold therapeutic benefit