Faktor yang Berhubungan dengan Keparahan Korban Kecelakaan Lalu Lintas pada Pengendara Sepeda Motor di Igd Rumah Sakit Umum Daerah Kota Kendari Tahun 2016

Kecelakaan lalu lintas adalah kejadian pada lalu lintas jalan yang sedikitnya diakibatkan oleh satu kendaraan yangmenyebabkan cedera, kerusakan, atau kerugian pada pemiliknya atau korban. Tujuan penelitian ini untukmengetahui mengetahui faktor yang berhubungan dengan keparahan korban kecelakaan lalu lintas padapengendara sepeda motor di IGD Rumah Sakit Umum Daerah Kota Kendari Tahun 2016. Metode penelitian iniadalah penelitian analitik dengan pendekatan cross sectional yaitu untuk mengetahui dinamika hubungan antaravariabel bebas suatu jenis penelitian dimana antara variabel bebas dan variabel terikat dilakukan secarabersamaan pada satu saat dengan kriteria data nominal atau or dinal. Penelitian ini dilaksanakan pada bulanFebruari 2016 dengan lokasi penelitian pada Rumah Sakit Umum Daerah Kota Kendari. Populasi dalam penelitianini sebanyak 895 orang, dan adapun sampel dalam penelitian ini berjumlah 90 orang. Hasil penelitianmenggunakan analisis chi square menunjukkan bahwa tidak ada hubungan antara penggunaan helm dengankeparahan korban kecelakaan lalu lintas sepeda motor pada pasien IGD RSUD Kota Kendari (P> α), bahwatidak ada hubungan antara penggunaan telepon seluler dengan keparahan korban kecelakaan lalu lintas sepedamotor pada pasien IGD RSUD Kota Kendari (P> α), terdapat hubungan antara kecepatan dengan keparahankorban kecelakaan lalu lintas sepeda motor pada pasien IGD RSUD Kota Kendari (PValue< α). Kesimpuln yangdidapatkan tidak terdapat hubungan antara penggunaan helm dan penggunaan telepon seluler keparahan korbankecelakaan lalu lintas pada pasien IGD RSUD Kota Kendari dan terdapat hubungan antara kecepatan dengankeparahan korban kecelakaan lalu lintas pada pasien IGD RSUD Kota Kendari

Program Death Ligan-1 (PD-L1) Expression in Invasif Breast Carcinoma of No Special Type

Breast carcinoma is the most frequently cancer in women (24%) and the main cause of cancer death in women worldwide. Based on data from globocan 2018 shows the incidence of breast cancer is around 2.08 million (11.6%) which is the second rank of all cancers after lung cancer with a mortality rate of 626.6 thousand (6.6%). However, prognosis of the breast carcinoma is influenced by several factors, including tumor histology grade and Tumor Infiltrating Lymphocytes (TILs). PD-L1 expression has been investigated as a potential biomarker and immune checkpoint to assess the response of various types of cancer. This study aims to determine PD-L1 expression in Invasive Breast Carcinoma of No Special Type (IBC-NST) grades 1,2 and 3. This study used a sample of 80 cases of paraffin block for IBC-NST patients from 2017 to 2020. There were 17 samples (21.3%) with grade 1, 32 samples (40%) with grade 2, and 31 samples (38.8%) with grade 3. The number of samples with positive PD-L1 expression were 63 samples, and 17 samples of negative PDL-1 expression were obtained. In the PD-L1 negative group, from a total of 17 samples, 4 samples were grade 1, 10 samples were grade 2, and 3 samples were grade 3. In the PD-L1 positive group, from a total of 63 samples, 13 samples with grade 1, 22 with grade 2, and 28 samples with grade 3. Based on the Chi-square test, p value = 0.115 (p &gt; 0.05). The proportion of PD-L1 expression was higher at higher grades. There was no significant difference in PD-L1 expression in IBC-NST grade 1, grade 2 and grade 3

Clinical Characteristics for Predicting Recurrency in Giant Cell Tumor of Bone

Giant Cell Tumor of Bone is classified as benign tumor with unpredictable biological behaviour. Recurrency and metastasis of GCTB could be found in this benign tumor. Many studies reported risk factor for recurrency of GCTB. This study is aimed to determine clinical factors for predict the recurrency in the giant cell tumour of the bone (GCTB). We collected clinical data of GCTB, included age, gender, location of tumor, radiographic, histopathological examination, then we classified GCTB samples into 3 groups, primary, recurrent, and metastatic based on the clinical and histopathological examination. From 52 samples, there were 34 samples of primary GCTB, 7 samples of recurrent GCTB or 13,5%, and 11 samples of GCTB metastatic or 21,1% from all samples GCTB. The incidens of recurrency was higher when the tumor destructed the cortex (Campanacci Grade 3), the location was in manus, and the intervention was curretage. There was a statistical significant difference recurrency between tumor location in manus and other locations (p&lt;0,05). Also, there was siginificant difference recurrency between wide excision and curretage (p&lt;0,05). We concluded that the clinical characteristics that could be predictors for recurrency are tumor location and method of surgery

Prevalence of Listeria spp. with PRS Genes in Fresh Vegetables from Traditional Markets

&nbsp; Listeriosis is a foodborne infectious disease caused by Listeria monocytogenes and is considered a serious health problem, due to the severity of symptoms and a high mortality rate in worldwide This study aims to identify and determine the prevalence of Listeria species through prs gene screening of fresh vegetables distributed in several markets of Makassar City. A total of 57 fresh vegetable samples were collected from February to May 2019 in four traditional markets Makassar. The isolates is examines to phenotypically and genotypically Vitek and Multiplex PCR with prs and lmo1030 primer. Phenotype analysis did not show the presence of Listeria species, but the results of genotypic was found 8 positive prs gene samples (14.03%), consisting of 31.2% long beans, 18.2% cabbage, and 9.1% cucumber and. All Listeria species found in this study is Listeria monocytogenes. This study also provide information and additional data that prs genes can be used as screening genotype for identify Listeria species in fresh vegetables.Listeriosis is a foodborne infectious disease caused by Listeria monocytogenes and is considered a serious health problem, due to the severity of symptoms and a high mortality rate in worldwide This study aims to identify and determine the prevalence of Listeria species through prs gene screening of fresh vegetables distributed in several markets of Makassar City. A total of 57 fresh vegetable samples were collected from February to May 2019 in four traditional markets Makassar. The isolates is examines to phenotypically and genotypically Vitek and Multiplex PCR with prs and lmo1030 primer. Phenotype analysis did not show the presence of Listeria species, but the results of genotypic was found 8 positive prs gene samples (14.03%), consisting of 31.2% long beans, 18.2% cabbage, and 9.1% cucumber and. All Listeria species found in this study is Listeria monocytogenes. This study also provide information and additional data that prs genes can be used as screening genotype for identify Listeria species in fresh vegetables

The Significance of Tumor-infiltrating Lymphocytes (TILs) in Histopathological Grading of Invasive Breast Carcinomas

Breast cancer is the leading cause of cancer death in women worldwide with high incidence rate. Invasive breast carcinoma is the most common form of breast cancer. Prognosis and survival rate of the patient is related with histopathological grading of the invasive breast carcinoma. Tumor-infiltrating lymphocytes (TILs) have been reported to be associated with patient clinical outcomes in a number of different malignant tumors. We studied the expression of TILs in invasive breast carcinoma using Hematoxylin Eosin (HE) staining. We studied the expression of are tumor-infiltrating lymphocytes (TILs) in paraffin block of tissue biopsy from breast tumor specimens.&nbsp;Immunohistochemistry was used to assess the expression of TILs in tumor breast tissue from 80 samples. Univariate and bivariate analyses assessed outcomes according to the expression of TILs in different histopathological grading.&nbsp;Of the 80 tumor specimens, 36 (45 %) of samples have high grade of TILs and 44 (55 %). On bivariate analysis, there were significant differences in the expression of TILs lymphocytes between well, moderately and poorly differentiated invasive breast carcinoma, respectively (p&lt; 0.0001). As a conclusion; we found that the severity of invasive breast carcinoma differentiation is directly related to the degree of TILs expression

c-Met overexpression in breast cancer with positive axillary lymph node

Background: Breast cancer is the second most common cancer in the world and is the most epidemic cancer in women, with approximately 1.67 million cases. Metastasis of tumor cells to other organs is a major cause of the increasing trend of mortality in breast cancer. This study aims to analyze the expression of c-Met associated with metastasis to axillary lymph nodes in invasive breast cancer.Method: The research was conducted at the Laboratory of Anatomical Pathology of Hasanuddin University Hospital. Stratified sampling was performed from January 2014 - January 2019. Immunohistochemical staining technique was applied upon 66 collected samples, followed by evaluating the c-Met expression score in invasive breast cancer group with positive and negative lymph node status.Result: c-Met overexpression was found among the invasive breast cancer incidence with lymph node metastasis. Among 50 cases with c-Met overexpression (c-Met positive), 40 cases (80%) of invasive breast cancer with lymph node metastasis were identified, while 10 cases (20%) were found in invasive breast cancer without metastasis to lymph nodes. On 16 cases with negative c-Met, 3 cases (18.8%) were found in invasive breast cancer with lymph node metastasis, and 13 cases (81.3%) in invasive breast cancer without metastasis to the lymph nodes. The statistical test results indicated a significant correlation between c-Met expression scores and metastasis to axillary lymph nodes in invasive breast cancer (p <0.001).Conclusion: As one of biomarkers, c-Met overexpression plays a vital role in the treatment of patients with invasive breast cancer to predict patient outcomes and to determine modalities. It is possible to apply c-Met overexpression to investigate aggressiveness of metastatic tumor cells in the future

Characteristics Based on Molecular Subtypes in Diffuse Large B-Cell Lymphoma Cases

Diffuse B-cell origin large cell lymphoma (DLBCL) is a type of non-Hodgkin's malignant lymphoma most commonly found in adults. Based on the gene or molecular expression profile, DLBCL can be divided into GCB (Germinal Center B-Cell-Like) and ABC / Non-GCB (Activated B-Cell-Like). However, identification of this grouping is still rarely done in Indonesia, especially Makassar City. This study aims to determine the characteristics of DLBCL cases based on molecular examination. This study used a sample of 44 cases of paraffin block for DLBCL patients from 2017 to 2019, then categorized using the Hans algorithm. Of the 44 cases, the number of GCB was 8 cases (18.2%) and ABC / Non-GCB 36 cases (81.8%). The incidence of female sex was slightly lower (47.7%) than in men (52.3%) with the most frequent location being nodal with 36 cases (81.8%) and extranodal as many as 8 cases (18.2%) . Meanwhile, age was found more frequently in patients with age &lt;60 years (32 cases, 72.7%) than those aged&gt; 60 years (12 cases, 27.3%) with a mean age of 52.57 years. The results showed that the ABC / Non-GCB type DLBCL was more common than the GCB type in patients in Makassar city

The Relationship of CXC Chemokine Receptor 4 (CXCR4) Expression with Histopathological Grading of Invasive Breast Cancer

Introduction: The histological grade of the tumor influences the prognosis of breast cancer. In metastatic breast cancer, the stromal cells produce a chemokine (C-X-C motif chemokine 12/CXCL12) or the so-called stromal-derived factor-1 (SDF-1) as a chemoattractant, which binds to the chemokine receptor (C-X-C chemokine receptor type 4/CXCR4) which is expressed by breast cancer cells. This study aimed to determine the expression of CXCR4 in invasive breast cancer associated with histopathological grading of invasive breast cancer. Methods: This study is observational with a retrospective approach using a paraffin block archive sample diagnosed with Invasive Breast Cancer. Immunohistochemical staining using CXCR4 antibody and expression analysis was performed by light microscopy. The data were statistically analyzed by the Chi-Square test and presented in the table. The statistical test results were significant if the p-value was &lt;0.05. Results: Showed no significant relationship between CXCR4 expression and histopathological grading in invasive breast cancer with a p-value = 0.467. Conclusion: The data of this study showed that the expression of CXCR4 in Invasive Breast Cancer varied and did not support its role in determining histopathological grading

TEACHING WRITING PROCEDURE TEXT THROUGH DO IT YOURSELF (DIY) VIDEO AT THE SECOND SEMESTER OF THE ENGLISH LANGUAGE EDUCATION STUDY PROGRAM IAIN PALOPO

ABSTRACT Andi Husni A. Zainuddin, 2022. “Teaching Writing Procedure Text Through Do It Yourself (DIY) Video at the Second Semester of English Language Education Study Program IAIN Palopo” A thesis of English Language Education Study Program of Tarbiyah and Teacher Training Faculty, State Islamic Institute of Palopo. Supervised by Abdul Pirol and Rusdiansyah. This research aims to determine whether the Do It Yourself video effectively improves writing skills in the procedure text at the second semester of the English Language Education Study Program IAIN Palopo. This research adopted the pre- experimental method. The sample consisted of thirty students. The Do It Yourself video was used as a medium in this research. The researcher collected the data through pre-test, treatment, and post-test. SPSS 22 edition was used to perform statistical analysis on the data. Investigation revealed that the mean post-test score is higher than the pre-test (47.80 < 81.36). Besides, the value of the t-count is higher than the value of the t-table. The result of the student's scores on the post- test became more elevated than opposed tests representing the treatment's effectiveness in helping the learners improve their writing skills. It could be summarized that using the Do It Yourself video significantly improved the students' writing skills, especially in writing procedure text. This research strongly emphasizes for the next researcher to examine the use of DIY videos for different skills imaginatively. Keywords: Do It Yourself video, procedure text, teaching writin

Persepsi Mahasiswa Terhadap Pembelajaran Selama Covid-19 Di Universitas Bosowa : Student's Perception at Learning Process During Covid-19 in Bosowa University

&nbsp; This study aims to describe (1) the implementation of sociology learning at the Sociology Study Program at Bosowa University, (2) students' perceptions of sociology learning at the Sociology Study Program at Bosowa University Makassar. This study uses a quantitative descriptive method with a survey approach to all 100 students of the sociology study program. The number of this population as well as the research sample. Data collection techniques used research instruments with a five-scale Likert scale, and literature study. Data analysis technique used frequency tabulation with percentage technique. The results of the study found: (1) The implementation of learning during the COVID-19 pandemic was categorized as 'Good' with a score of 245, sometimes 50, Bad 49. (2) Respondents' perceptions of the implementation of learning during the COVID-19 pandemic were categorized as 'Good' (Score 322). , Average (Score 44), Bad (Score 9). The conclusion of the study is that students' perceptions of learning during the Covid-19 Pandemic at the University of Bosowa are categorized as 'Good'. The recommendation of this research is the need for teachers to innovate learning in the post-pandemic era in order to keep up with the times. &nbsp; Penelitian ini bertujuan untuk menggambarkan (1) implementasi pembelajaran sosiologi di Program studi sosiologi Universitas Bosowa, (2) persepsi mahasiswa terhadap pembelajaran sosiologi di program studi sosiologi Universitas Bosowa Makassar. Penelitian ini menggunakan metode deskriptif kuantitatif dengan pendekatan suvei terhadap semua jumlah mahasiswa program studi sosiologi sebanyak 100 orang. Jumlah populasi ini sekaligus juga sebagai sampel penelitian. Teknik pengumpulan data mempergunakan instrumen penelitian dengan Skala Likert lima skala, dan studi kepustakaan. Teknik analisis data menggunakan tabulasi frekuensi dengan teknik persentase. Hasil penelitian menemukan : (1) Implementasi pembelajaran selama pandemi covid-19 terkategori ‘Baik' dengan nilai 245, kadang-kadang 50, Buruk 49. (2) Persepsi responden terhadap implementasi pembelajaran selama pandemi covid-19 terkategori ‘Baik' (Nilai 322), Biasa (Nilai 44), Buruk (Nilai 9). Kesimpulan penelitian adalah persepsi mahasiswa terhadap pembelajaran selama Pandemi Covid-19 di Universitas Bosowa terkategori ‘Baik'. Rekomendasi penelitian ini adalah perlunya para guru melakukan inovasi pembelajaran di era post-pandemi agar dapat mengikuti perkembangan zaman