A universal relation for the stress dependence of activation energy for slip in body-centered cubic crystals

By analyzing experimental data in the literature, the activation energy H for slip in body-centered cubic metals is found to approximately obey the simple relation H≈0.1 μb3(1 - t)2, where t is the applied stress normalized by the zero-temperature Peierls stress, μ is the 〈111〉 shear modulus, and b the 1/2〈111〉 Burgers vector. Such universal relation is explained by analyzing the activation processes of kink-pair generation and expansion along threefold screw dislocations using the generalized Peierls-Nabarro model [A. H. W. Ngan, J. Mech. Phys. Solids 45, 903 (1997)]. The model also predicts qualitatively the general form of the orientation dependence of Peierls stress at zero temperature. © 1999 American Institute of Physics.published_or_final_versio

A tale of two population crises in recent Chinese history

The fall of the Ming dynasty in the first half of the 17th century and the Taiping Rebellion from 1851-1864 were two of the most chaotic periods in Chinese history, and each was accompanied by large-scale population collapses. The 'Kang-Qian Golden Age' (also known as 'High Qing'), during which population size expanded rapidly, falls in between the two. Scholars remain divided in their opinions concerning the above alternation of population growth and decline as to whether variations in population size or climate change should be identified as the root cause. In either case, the synergistic impact of population growth and climate change upon population growth dynamics is overlooked. In the present study, we utilized high-resolution empirical data, qualitative survey, statistical comparison and time-series analysis to investigate how the two factors worked synergistically to drive population cycles in 1600-1899. To facilitate our research, we posited a set of simplified pathways for population growth in historical agrarian China. Our results confirm that the interrelation between population growth, climate change and population crises in recent Chinese history basically followed our posited pathways. The recurrences of population crises were largely determined by the combination of population growth and climate change. Our results challenge classic Malthusian/post-Malthusian interpretations and historians' views of historical Chinese population cycles. © 2012 The Author(s).published_or_final_versionSpringer Open Choice, 28 May 201

Managerial entrenchment and firm value: a dynamic perspective

We examine the impact of managerial entrenchment on firm value using a dynamic model with firm fixed effects. To estimate the model, we employ the long-difference technique, which is shown by our simulation to deliver the least biased estimates. Based on a large sample of U.S. companies, we document a significantly negative and causal effect of managerial entrenchment on firm value after taking into account omitted variables, reverse causality, and highly persistent endogenous variables. Additional analysis suggests that the causality running from managerial entrenchment to firm value is more pronounced than that for reverse causality.Chang acknowledges financial support from Academic Research Fund Tier 1 provided by Ministry of Education (Singapore). Zhang acknowledges the financial supports for his PhD research from the University of Melbourne

Protein-complex structure completion using IPCAS (Iterative Protein Crystal structure Automatic Solution)

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Online pricing for multi-type of Items

LNCS v. 7285 entitled: Frontiers in algorithmics and algorithmic aspects in information and management: joint international conference, FAW-AAIM 2012 ... proceedingsIn this paper, we study the problem of online pricing for bundles of items. Given a seller with k types of items, m of each, a sequence of users {u 1, u 2, ...} arrives one by one. Each user is single-minded, i.e., each user is interested only in a particular bundle of items. The seller must set the price and assign some amount of bundles to each user upon his/her arrival. Bundles can be sold fractionally. Each u i has his/her value function v i (·) such that v i (x) is the highest unit price u i is willing to pay for x bundles. The objective is to maximize the revenue of the seller by setting the price and amount of bundles for each user. In this paper, we first show that the lower bound of the competitive ratio for this problem is Ω(logh + logk), where h is the highest unit price to be paid among all users. We then give a deterministic online algorithm, Pricing, whose competitive ratio is O (√k·log h log k). When k = 1 the lower and upper bounds asymptotically match the optimal result O(logh). © 2012 Springer-Verlag.postprin

Human cardiac Kv4.3 channels are regulated by protein tyrosine kinases

Poster presentationpublished_or_final_versionThe 15th Annual Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong, 16 January 2010. In Hong Kong Medical Journal, 2010, v. 16, suppl. 1, p. 64, abstract no. 11

Online algorithms for 1-space bounded multi dimensional bin packing and hypercube packing

In this paper, we study 1-space bounded multi-dimensional bin packing and hypercube packing. A sequence of items arrive over time, each item is a d-dimensional hyperbox (in bin packing) or hypercube (in hypercube packing), and the length of each side is no more than 1. These items must be packed without overlapping into d-dimensional hypercubes with unit length on each side. In d-dimensional space, any two dimensions i and j define a space P ij. When an item arrives, we must pack it into an active bin immediately without any knowledge of the future items, and 90 {ring operator}-rotation on any plane P ij is allowed. The objective is to minimize the total number of bins used for packing all these items in the sequence. In the 1-space bounded variant, there is only one active bin for packing the current item. If the active bin does not have enough space to pack the item, it must be closed and a new active bin is opened. For d-dimensional bin packing, an online algorithm with competitive ratio 4 d is given. Moreover, we consider d-dimensional hypercube packing, and give a 2 d+1-competitive algorithm. These two results are the first study on 1-space bounded multi dimensional bin packing and hypercube packing. © 2012 The Author(s).published_or_final_versionSpringer Open Choice, 28 May 201

Regional Geographic Factors Mediate the Climate-war Relationship in Europe

It has been demonstrated in recent studies by that wars occurred with greater frequency in Europe in periods of cold climate over the past millennium, and food scarcity is the explanation. However, the issue of whether the climate-war relationship holds consistently across the European continent has been insufficiently explored. In the present study, we seek to advance the macroscopic understanding of the climate-war association in Europe via the statistical analysis of fine-grained paleo-climate and historical warfare data covering the period 1400–1999, with a specific focus on how regional geographic factors mediate the association. Our statistical results show that the climate-war correlation varied across Europe. At multi-centennial time-scale, temperature-war correlation was stronger in Eastern Europe, in part because of the region’s greater dependence on agriculture and in part due to the region’s prevailing continental climate. At multi-decadal to centennial time-scale, the temperature-war correlation in Europe was periodically distorted when population pressure was unleashed via a significant decline in the rate of population growth or through industrialization. Furthermore, the regional disparity in terms of population growth rate and pace of industrialization might be responsible for the diverse trends and trajectories of the temperature-war correlation in Eastern Europe and Western Europe. Our results may help to resolve some major controversies about the climate-conflict link.published_or_final_versio

Regulation of cell proliferation by ion channels in human mesenchymal stem cells

Oral presentationpublished_or_final_versionThe 15th Annual Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong, 16 January 2010. In Hong Kong Medical Journal, 2010, v. 16, suppl. 1, p. 65, abstract no. 11

Quantifying the intra-regional precipitation variability in northwestern China over the past 1,400 years

There has been a surge of paleo-climatic/environmental studies of Northwestern China (NW China), a region characterized by a diverse assortment of hydro-climatic systems. Their common approach, however, focuses on "deducing regional resemblance" rather than "exploring regional variance." To date, efforts to produce a quantitative assessment of long-term intra-regional precipitation variability (IRPV) in NW China has been inadequate. In the present study, we base on historical flood/drought records to compile a decadal IRPV index for NW China spanned AD580-1979 and to find its major determinants via wavelet analysis. Results show that our IRPV index captures the footprints of internal hydro-climatic disparity in NW China. In addition, we find distinct similar to 120-200 year periodicities in the IRPV index over the Little Ice Age, which are attributable to the change of hydro-climatic influence of ocean-atmospheric modes during the period. Also, we offer statistical evidence of El Nino Southern Oscillation (Indo-Pacific warm pool sea surface temperature and China-wide land surface temperature) as the prominent multi-decadal to centennial (centennial to multi-centennial) determinant of the IRPV in NW China. The present study contributes to the quantitative validation of the long-term IRPV in NW China and its driving forces, covering the periods with and without instrumental records. It may help to comprehend the complex hydro-climatic regimes in the region.published_or_final_versio