Modern nanochemistry : nanotechnology science and technology

x, 164 hlm.; ilus.; 22 cm

5-Hydroxy-6-Methyluracil as a Polyvinyl Chloride Stabilizer

Kinetic regularities of thermooxidative dehydrochlorination of rigid and plasticized PVC in the presence of 5-hydroxy-6-methyluracil have been studied. The high antioxidant efficacy of 5-hydroxy-6-methyluracil in the process of polymer degradation has been revealed. It is shown that the studied uracil significantly slows down the process of accumulation of hydroperoxides in oxidation of dioctyl phthalate the plasticizer of PVC, which is the cause of a significant slowdown in the rate of decomposition of the plasticized polymer

Metabolic Oxidation Of Dipyridamole(dip) By Mouse Liver Microsomes

A method of spectrofluorimetric monitoring of dipyridamole (DIP) metabolism has been developed. The spectrophotometric monitoring of NADPH microsomal oxidation as a measure of DIP metabolism has also been performed. The drug metabolic oxidation by microsomes requires NADPH and is accompanied by the oxidation of both cofactor and cytochrome b5. Carbon monoxide inhibits DIP metabolic oxidation.211120126Mancuso, G., (1995) Genitourinary Medicine, 71, p. 57Selley, M.L., (1994) Atherosclerosis, 111, p. 91Pospisil, M., (1995) Rad. Res., 142, p. 16Snoek, R., (1994) Antiviral Chemistry & Chemotherapy, 5, p. 312Sato, S., (1993) Anti-cancer Drug Design, 8, p. 289Damile, B.D., (1994) Int J. Cancer, 56, p. 113Vallejo, C.T., (1995) Amer. J. Clin. Oncol., 18, p. 185Ragazzi, E., (1995) Int. J. Oncol., 6, p. 659Iuliano, L., (1992) Lipids, 27, p. 349Lowry, O.H., (1951) Biol Chem., 193, p. 265Omura, T., Sato, R., (1964) J. Biol. Chem., 239, p. 2371Degterev, I.A., (1990) Pharmac. Chem. J., 24, p. 9Verovskiy, V.N., (1990) Pharmac. Chem. J., 24, p. 20Degterev, I.A., (1993) Bioactive Compounds. Biotransformation and Biological Action, , NOVA Science Publ., New Yor

Mice Liver Microsomes Stabilize Erythrocytes With Respect To Lysis Induced By Trifluoroperazine

[No abstract available]3011671674Seeman, P., (1972) Pharmacol. Rev., 24, pp. 583-655Minetti, M., Di Stasi, A.M.M., (1987) Biochemistry, 26, pp. 8133-8137Yamaguchi, T., Watanabe, S., Kimoto, E., (1985) Biochim. Biophys. Acta, 820, pp. 157-164Vazquez, A., Tudela, J., Varon, E., (1992) Anal. Biochem., 202, pp. 245-248Vazquez, A., Tudela, J., Varon, E., (1992) Biochem. Pharmacol., 44, pp. 889-894Aki, H., Yamamoto, M., (1989) Biochem. Pharmacol., 39, pp. 396-398Omura, T., Sato, R., (1964) J. Biol. Chem., 239, pp. 2371-2385Chargaf, E., (1957) Nucleic Acids, 1, pp. 450-483. , E. Chargaf and J. N. Davidson (eds.), Academis Press, New YorkSeeman, P., (1966) Biochem. Pharmacol., 15, pp. 1737-1752Pereira, R.S., Bertocci, A.P.F., Vercesi, A.E., (1992) Biochem. Pharmacol., 41, pp. 1-

Hemocompatibility of ultrafine systems on the basis of chitosan and its derivatives polymer-colloid complexes

This article presents the results of the development process for the preparation of micro and nano-sized polymer-colloid com-plexes (РСС) on the basis of water-soluble natural polymer chitosan (СTZ) and the sodium salt of chitosan succinylamid (SСTZ) with silver halide sols in aqueous media. Results of research of СTZ, sodium salt of SСTZ solutions and PСС of CTZ and SСTZ with colloidal parti-cles of silver iodide influence on structurally-functional properties of erythrocytes’ membranes on model of acidic hemolisis are presented in the article. Their influence on the nature of erythrocytes distribution by degree of their stability and on kinetic parameters (the beginning, intensity and completion of process of their destruction) under the influence of the damaging agent (HCl) is shown. The comparative analysis of results convinces that СTZ, SСTZ solutions and disperse systems on the basis of PСС of СTZ and SСTZ with colloidal particles of the silver iodide are capable of modulating variously matrix properties of erythrocytes of blood

Hemocompatibility of ultrafine systems on the basis of chitosan and its derivatives polymercolloid complexes

This article presents the results of the development process for the preparation of micro and nano-sized polymer-colloid com-plexes (РСС) on the basis of water-soluble natural polymer chitosan (СTZ) and the sodium salt of chitosan succinylamid (SСTZ) with silver halide sols in aqueous media. Results of research of СTZ, sodium salt of SСTZ solutions and PСС of CTZ and SСTZ with colloidal parti-cles of silver iodide influence on structurally-functional properties of erythrocytes’ membranes on model of acidic hemolisis are presented in the article. Their influence on the nature of erythrocytes distribution by degree of their stability and on kinetic parameters (the beginning, intensity and completion of process of their destruction) under the influence of the damaging agent (HCl) is shown. The comparative analysis of results convinces that СTZ, SСTZ solutions and disperse systems on the basis of PСС of СTZ and SСTZ with colloidal particles of the silver iodide are capable of modulating variously matrix properties of erythrocytes of blood