884 research outputs found
A CHILD WITH NARCOLEPSY
Introdução: A Narcolepsia Ă© uma doença crĂłnica caracterizada por ataques de sono, sonolĂȘncia diurna excessiva e fragmentação do sono noturno. Pode associar-se a cataplexia e a outros fenĂłmenos do sono REM (paralisia do sono e alucinaçÔes hipnagĂłgicas e hipnopĂŽmpicas).
Caso clĂnico: Um menino de 10 anos foi enviado Ă consulta de Pedopsiquiatria por alteraçÔes do comportamento, irritabilidade, adormecimento fĂĄcil e distração, sendo interpretado como uma âcriança mal-educadaâ. ApĂłs avaliação clĂnica e estudo concluiu-se que apresentava narcolepsia com cataplexia.
Discussão/conclusão: Os doente com narcolepsia confrontam-se com vårios problemas devido à própria doença que, se não tratada ou tratada ineficazmente, provoca sintomas perturbadores ou embaraçosos, influenciando a sua qualidade de vida.
O objetivo deste trabalho Ă© chamar a atenção para este problema uma vez que Ă© uma situação rara e por isso tambĂ©m muitas vezes desconhecida pelo pĂșblico em geral e atĂ© pelos profissionais de saĂșde.Introduction: Narcolepsy is a chronic disease characterized by sleep attacks, excessive daytime sleepiness and nocturnal sleep fragmentation. It can be associated cataplexy and other
disturbance of REM sleep (sleep paralysis and hypnagogic hallucinations and hypnopompic).
Case report: A 10-year old boy was referred to Pedopsychiatry because of behavioural disturbance, irritability, sleepiness and distraction, being interpreted as an âill-mannered child.â After clinical evaluation and comprehensive laboratory studies we concluded that he presented narcolepsy with cataplexy.
Discussion/conclusion: Patients with narcolepsy face several problems due to the disease which, if left untreated or ineffectively treated, cause embarrassing or distressing symptoms, affecting their quality of life.
The purpose of this paper is to draw attention to this problem since it is a rare condition and therefore
seldom not recognized by the general public or even by health professionals
Fabrication and Electrical Characterization of Translucent Bi 12
The production of high-density Bi12TiO20 ceramics, their transmission spectrum, and impedance features are reported. The samples were synthesized at 700°C/6âh and sintered at 800°C/3âh. This procedure yielded translucent ceramics with relative density of 99.2±0.5% and average grain size of 3.1±1.6âÎŒm. Samples with 0.5âmm thickness were translucent with optical transmission of about 30% at 800ânm. The electrical and dielectric properties of the high-density ceramics were studied and compared with those measured for samples with lower density and also with the literature about Bi12TiO20 single crystals. The activation energy for the conduction process in high-density ceramic was 0.99âeV, and the dielectric permittivity was 40 at 200°C. These values are comparable to those reported for single crystals
Comparação da produção de poliedroses de SfMNPV em células de inseto SF9 e SF21.
IX SINCOBIOL
FĂłsforo e humoativo BMÂź no desenvolvimento, produtividade e qualidade de raĂzes de mandioca, em Belmonte, Bahia.
Os solos da RegiĂŁo FisiogrĂĄfica do Extremo Sul da Bahia, na sua maioria, apresentam fertilidade natural baixa, com nĂveis de nitrogĂȘnio e fĂłsforo geralmente a nĂveis crĂticos de exigĂȘncia, conduzindo a produtividades significativamente inferiores a capacidade produção das culturas. Os agricultores, em sua maioria nĂŁo corrigem a fertilidade do solo, e quando o fazem, aplicam na quantidade e de forma errĂŽnea, reduzindo a capacidade de resposta das plantas.Fertilidade do solo. Resumo 251
Fracionamento de substĂąncias hĂșmicas em Organossolos: um subsĂdio Ă modelagem de dinĂąmica de carbono em ambientes terrestres.
O trabalho pesquisou as relaçÔes das fraçÔes hĂșmicas com atributos dos Organossolos, visando embasar novas pesquisas relacionadas ao manejo do carbono nesses solos
Electrical and Dielectric Characterization of Bi 12
Bismuth germanate (Bi12GeO20) ceramics were produced using modified Pechini route, and the synthesis parameters, crystalline phases, microstructure, and sintering conditions were investigated. Bi12GeO20 powders with submicrometric particle sizes were investigated for calcination temperatures from 400 to 600°C, with soaking times of 1âh and 5âh. Controlling the synthesis parameters, dense ceramics with two different grain sizes of 3.4 ± 0.5â”m and 5.7 ± 0.8â”m could be produced after sintering at 750°C/1âh. The electric and dielectric properties of these ceramics were determined by impedance spectroscopy (IS). From the results, it was concluded that the dielectric permittivity measured at high frequencies is insensitive to the grain size, while the AC dark conductivity presents a noticeable dependency on this feature. This behaviour was discussed on the basis of a Maxwell-Wagner interfacial relaxation, whose intensity depends directly on the volume fraction of grain boundaries in the sample
MIRRAGGE â Minimum Information Required for Reproducible AGGregation Experiments
Reports on phase separation and amyloid formation for multiple proteins and aggregation-prone peptides are recurrently used to explore the molecular mechanisms associated with several human diseases. The information conveyed by these reports can be used directly in translational investigation, e.g., for the design of better drug screening strategies, or be compiled in databases for benchmarking novel aggregation-predicting algorithms. Given that minute protocol variations determine different outcomes of protein aggregation assays, there is a strong urge for standardized descriptions of the different types of aggregates and the detailed methods used in their production. In an attempt to address this need, we assembled the Minimum Information Required for Reproducible Aggregation Experiments (MIRRAGGE) guidelines, considering first-principles and the established literature on protein self-assembly and aggregation. This consensus information aims to cover the major and subtle determinants of experimental reproducibility while avoiding excessive technical details that are of limited practical interest for non-specialized users. The MIRRAGGE table (template available in Supplementary Information) is useful as a guide for the design of new studies and as a checklist during submission of experimental reports for publication. Full disclosure of relevant information also enables other researchers to reproduce results correctly and facilitates systematic data deposition into curated databases.This work was supported by (i) the European Regional Development Fund (ERDF) through the COMPETE 2020âOperacional Programme for Competitiveness and Internationalisation (POCI), Portugal 2020, and by Portuguese funds through FCTâFundação para a CiĂȘncia e a Tecnologia (FCT/MCTES) in the framework of grants POCI-01-0145-FEDER-031173, POCI-01-0145-FEDER-007274, POCI-01-0145-FEDER-031323 (âInstitute for Research and Innovation in Health Sciencesâ), UID/Multi/04046/2013 (BioISI) and PTDC/NEUNMC/2138/2014 (to CMG). SV was funded by the Spanish Ministry of Economy and Competitiveness (BIO2016-78310-R) and by ICREA (ICREA-Academia 2015). ZG and ZB were funded by Slovak research agentures VEGA 02/0145/17, 02/0030/18 and APVV-18-0284. RS was funded by VEGA 02/0163/19. DEO was funded by the Lundbeck Foundation (grant no. R276-2018-671) and the Independent Research Foundation Denmark | Natural Sciences (grant no. 8021-00208B). AP research was supported by UK Dementia Research Institute (RE1 3556) and by ARUK (ARUK-PG2019B-020)
Short Time and Low Temperature Reaction between Metal Oxides through Microwave-Assisted Hydrothermal Method
This work demonstrates the possibility of synthesis of cadmium tungstate at low temperatures using oxide precursors. Cadmium tungstate (CdWO4) scintillator was produced via microwave-assisted hydrothermal reaction using the precursors CdO and WO3. The methodology was based on microwave radiation for heating, which is remarkably faster than the solid-state route or conventional hydrothermal procedure. CdWO4 monoclinic (wolframite) structure was successfully obtained at 120°C for synthesis times as short as 20âmin. This route does not require the use of templates or surfactants and yields self-assembled nanorods with size of around 24 ± 9ânm width and 260 ± 47ânm length. The growth mechanism for the formation of CdWO4 involves microwave-induced dissociation of the reagents and solvation of Cd2+ and WO42- ions, which are free to move and start the nucleation process. The luminescence properties of the produced nanoparticles were investigated, presenting a broad emission band at around 500ânm, which is comparable to that observed for samples produced using other chemical routes. This result highlights the great potential of the proposed method as a low-cost and time saving process to fabricate luminescent oxide nanoparticles
Fast relaxation in a fragile liquid under pressure
The incoherent dynamic structure factor of ortho-terphenyl has been measured
by neutron time-of-flight and backscattering technique in the pressure range
from 0.1 MPa to 240 MPa for temperatures between 301 K and 335 K.
Tagged-particle correlations in the compressed liquid decay in two steps. The
alpha-relaxation lineshape is independent of pressure, and the relaxation time
proportional to viscosity. A kink in the amplitude f_Q(P) reveals the onset of
beta relaxation. The beta-relaxation regime can be described by the
mode-coupling scaling function; amplitudes and time scales allow a consistent
determination of the critical pressure P_c(T). alpha and beta relaxation depend
in the same way on the thermodynamic state; close to the mode-coupling
cross-over, this dependence can be parametrised by an effective coupling Gamma
~ n*T**{-1/4}.Comment: 4 Pages of RevTeX, 4 figures (submitted to Physical Review Letters
A Human-Health Risk Assessment for West Nile Virus and Insecticides Used in Mosquito Management
West Nile virus (WNV) has been a major public health concern in North America since 1999, when the first outbreak in the Western Hemisphere occurred in New York City. As a result of this ongoing disease outbreak, management of mosquitoes that vector WNV throughout the United States and Canada has necessitated using insecticides in areas where they traditionally have not been used or have been used less frequently. This has resulted in concerns by the public about the risks from insecticide use. The objective of this study was to use reasonable worst-case risk assessment methodologies to evaluate human-health risks for WNV and the insecticides most commonly used to control adult mosquitoes. We evaluated documented health effects from WNV infection and determined potential population risks based on reported frequencies. We determined potential acute (1-day) and subchronic (90-day) multiroute residential exposures from each insecticide for several human subgroups during a WNV disease outbreak scenario. We then compared potential insecticide exposures to toxicologic and regulatory effect levels. Risk quotients (RQs, the ratio of exposure to toxicologic effect) were < 1.0 for all subgroups. Acute RQs ranged from 0.0004 to 0.4726, and subchronic RQs ranged from 0.00014 to 0.2074. Results from our risk assessment and the current weight of scientific evidence indicate that human-health risks from residential exposure to mosquito insecticides are low and are not likely to exceed levels of concern. Further, our results indicate that, based on human-health criteria, the risks from WNV exceed the risks from exposure to mosquito insecticides
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