Detailed profiles for the genes which were within the sector shown in the previous h-profile plot

<p><b>Copyright information:</b></p><p>Taken from "h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data"</p><p>http://www.biomedcentral.com/1471-2105/8/486</p><p>BMC Bioinformatics 2007;8():486-486.</p><p>Published online 20 Dec 2007</p><p>PMCID:PMC2257978.</p><p></p> The gene expression values are shown on the vertical axis on the left, and on the right, the mean centered gene expression profiles are shown. The profile of CLN1 is shown as a red solid bold line. All these genes have a correlation of .74 or higher with CLN1. The phase identification on the top axis identifies the first of the two samples which were identified to belong to the phase by Cho [12]

H-Profile plot using 352 genes selected from the Cho data set using equation 5 with a critical cutoff estimated using the third quartile of the simulated values of

<p><b>Copyright information:</b></p><p>Taken from "h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data"</p><p>http://www.biomedcentral.com/1471-2105/8/486</p><p>BMC Bioinformatics 2007;8():486-486.</p><p>Published online 20 Dec 2007</p><p>PMCID:PMC2257978.</p><p></p> The profile plots show a time series plot of the transformed gene expression values, colored according to the phase in which the maximum gene expression value occurred. A number of gene profiles on the outer edge of the bulk of the thumbnails are identified, all of which were in de Lichtenberg 's top 300 list [11] and 9 in the Cho [12] list. By the geometry of the h-profile plot these genes can be expected to have the highest variance amongst the selected genes and therefore, in the sense of de Lichtenberg , to be strongly regulated

Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets-3

<p><b>Copyright information:</b></p><p>Taken from "Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets"</p><p>http://www.biomedcentral.com/1471-2164/8/404</p><p>BMC Genomics 2007;8():404-404.</p><p>Published online 7 Nov 2007</p><p>PMCID:PMC2219888.</p><p></p>aveolin-1 in both endothelial cells (EC: A-C) and in smooth muscle cells (SMC: D-F) of saphenous arteries taken from SHR (B, E) and ACTH (C, F), compared to WKY (A, D). Arrows indicate staining delineating the membranes of smooth muscle cells (D-F). Preincubation of the antibody with the immunogen eliminated staining in both endothelium and smooth muscle (G). Calibration bars represent 25 μm

Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets-1

<p><b>Copyright information:</b></p><p>Taken from "Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets"</p><p>http://www.biomedcentral.com/1471-2164/8/404</p><p>BMC Genomics 2007;8():404-404.</p><p>Published online 7 Nov 2007</p><p>PMCID:PMC2219888.</p><p></p>he position of each array is shown as a label joined by a dotted line to the origin. B. A heat map (white: up-regulated; red: down-regulated) using hierarchical clustering with complete linkage for the columns only. The rank order of the p-values, gene names and Affymetrix IDs are included on the right and correspond to the numbering in A

Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets-5

<p><b>Copyright information:</b></p><p>Taken from "Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets"</p><p>http://www.biomedcentral.com/1471-2164/8/404</p><p>BMC Genomics 2007;8():404-404.</p><p>Published online 7 Nov 2007</p><p>PMCID:PMC2219888.</p><p></p>10 μm